rpcardioRational Pharmacotherapy in CardiologyРациональная Фармакотерапия в Кардиологии1819-64462225-3653«SILICEA-POLIGRAF» LLC10.20996/1819-6446-2006-2-1-59-63rpcardio-1006Research ArticlePOINT OF VIEWТОЧКА ЗРЕНИЯANTIHYPERTENSIVE TREATMENT IN ELDERLY PATIENTS WITH DIHYDROPYRIDINE CALCIUM ANTAGONISTSПРИМЕНЕНИЕ ДИГИДРОПИРИДИНОВЫХ АНТАГОНИСТОВ КАЛЬЦИЯ У ПОЖИЛЫХ БОЛЬНЫХ АРТЕРИАЛЬНОЙ ГИПЕРТОНИЕЙКарповЮ. А.KarpovY. A.БузаВ. В.BuzaV. V.ФГУ РКНПК РосздраваРоссияRussian cardiological research and production complex of RoszdravRussian Federation200623012016215963Copyright © Karpov Y.A., Buza V.V., 20162016Карпов Ю.А., Буза В.В.Karpov Y.A., Buza V.V.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.rpcardio.online/jour/article/view/1006

The proofs of necessity of active arterial hypertension (AH) treatment in elderly patients are given. Peculiarities of pathogenesis of AH in elderly patients, connected predominantly with loss of big arteries elasticity and reasoning widely spread of isolated systolic AH in these patients, are discussed. Advantages of dihydropyridine calcium antagonists (DPCA) for AH treatment in elderly patients are proved, safety of treatment with DPCA is discussed. Data of clinical studies is analyzed. Analysis of target levels of blood pressure for antihypertensive treatment in elderly hypertensive patients is made. As a conclusion DPCA are the medicines of choice for AH treatment in elderly patients.

Приводится доказательства относительно необходимости активного лечения артериальной гипертонии (АГ) у пожилых больных. Обсуждаются особенности патогенеза АГ у лиц пожилого возраста, связанные с преимущественной потерей эластических свойств крупных артерий и объясняющие высокую распространенность у них изолированной систолической АГ. Обосновываются преимущества дигидропиридиновых антагонистов кальция (ДПАК) в лечении АГ у пожилых больных, рассматриваются вопросы безопасности их применения. Анализируются данные клинических исследований. Проводится анализ целевых уровней артериального давления при антигипертензивном лечении пожилых больных АГ. Делается заключение о том, что ДПАК являются препаратами выбора для лечения АГ у пожилых больных.

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The authors declare that there are no conflicts of interest present.