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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">rpcardio</journal-id><journal-title-group><journal-title xml:lang="en">Rational Pharmacotherapy in Cardiology</journal-title><trans-title-group xml:lang="ru"><trans-title>Рациональная Фармакотерапия в Кардиологии</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1819-6446</issn><issn pub-type="epub">2225-3653</issn><publisher><publisher-name>«SILICEA-POLIGRAF» LLC</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.20996/1819-6446-2016-12-1-79-86</article-id><article-id custom-type="elpub" pub-id-type="custom">rpcardio-1205</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>POINT OF VIEW</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ТОЧКА ЗРЕНИЯ</subject></subj-group></article-categories><title-group><article-title>Pharmacotherapy of pulmonary hypertension (according to the 2015 ESC/EAS Guidelines for the diagnosis and treatment of pulmonary hypertension)</article-title><trans-title-group xml:lang="ru"><trans-title>МЕДИКАМЕНТОЗНОЕ ЛЕЧЕНИЕ ЛЕГОЧНОЙ ГИПЕРТЕНЗИИ (ПО МАТЕРИАЛАМ 2015 ESC/ERS GUIDELINES FOR THE DIAGNOSIS AND TREATMENT OF PULMONARY HYPERTENSION)</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Трисветова</surname><given-names>Е. Л.</given-names></name><name name-style="western" xml:lang="en"><surname>Trisvetova</surname><given-names>E. L.</given-names></name></name-alternatives><bio xml:lang="ru"><p>д.м.н., профессор, профессор 2-й кафедры внутренних болезней Белорусского государственного медицинского университета</p></bio><email xlink:type="simple">trisvet-47@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Губкин</surname><given-names>С. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Gubkin</surname><given-names>S. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>д.м.н., профессор, первый проректор Белорусского государственного медицинского университета</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Белорусский государственный медицинский университет. 220116, Минск, проспект Дзержинского, 83</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Belarusian State Medical University. Prospect Dzerzhinskogo 83, Minsk, 220116 Belorussia</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2016</year></pub-date><pub-date pub-type="epub"><day>09</day><month>03</month><year>2016</year></pub-date><volume>12</volume><issue>1</issue><fpage>79</fpage><lpage>86</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Trisvetova E.L., Gubkin S.V., 2016</copyright-statement><copyright-year>2016</copyright-year><copyright-holder xml:lang="ru">Трисветова Е.Л., Губкин С.В.</copyright-holder><copyright-holder xml:lang="en">Trisvetova E.L., Gubkin S.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.rpcardio.online/jour/article/view/1205">https://www.rpcardio.online/jour/article/view/1205</self-uri><abstract><p>Indications and efficacy of drugs used for the treatment of pulmonary hypertension are considered. Stages of the treatment of pulmonary arterial hypertension are discussed, including maintenance therapy, specific therapy with calcium channel blockers, prostacyclin analogues, endothelin receptor antagonists, phosphodiesterase-5 inhibitors, prostacyclin agonists, guanylate cyclase stimulators, combination treatment.</p></abstract><trans-abstract xml:lang="ru"><p>Рассматриваются показания и эффективность лекарственных препаратов, применяемых для лечения легочной гипертензии. Обсуждаются этапы лечения легочной артериальной гипертензии, включающие поддерживающую терапию, специфическую терапию блокаторами кальциевых каналов, аналогами простациклина, антагонистами рецепторов эндотелина, ингибиторами фосфодиэстеразы-5, агонистами простациклина, стимуляторами гуанилатциклазы, комбинированную терапию.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>легочная артериальная гипертензия</kwd><kwd>поддерживающая терапия</kwd><kwd>специфическая терапия</kwd><kwd>комбинированная терапия</kwd></kwd-group><kwd-group xml:lang="en"><kwd>pulmonary arterial hypertension</kwd><kwd>maintenance therapy</kwd><kwd>specific pharmacotherapy</kwd><kwd>combination treatment</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Galiè N., Humbert M., Jean-Luc Vachiery J-L., et al. 2015 ESC/ERS Guidelines for the diagnosis and treatment of pulmonary hypertension. 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