rpcardioRational Pharmacotherapy in CardiologyРациональная Фармакотерапия в Кардиологии1819-64462225-3653«SILICEA-POLIGRAF» LLC10.20996/1819-6446-2016-12-3-277-284rpcardio-1269Research ArticleORIGINAL STUDIESОРИГИНАЛЬНЫЕ ИССЛЕДОВАНИЯESTIMATION OF RIGHT VENTRICULAR DIASTOLIC FUNCTION IN PATIENTS WITH ISCHEMIC HEART DISEASE IN DIFFERENT AGE GROUPSОЦЕНКА ДИАСТОЛИЧЕСКОЙ ФУНКЦИИ ПРАВОГО ЖЕЛУДОЧКА У БОЛЬНЫХ ИШЕМИЧЕСКОЙ БОЛЕЗНЬЮ СЕРДЦА В РАЗНЫХ ВОЗРАСТНЫХ ГРУППАХГайфулинР. А.GajfulinR. A.

к.м.н., н.с. лаборатории интервенционных методов диагностики и лечения отдела мультифокального атеросклероза НИИ КПССЗ

rus_gayf@mail.ruСуминА. Н.SuminA. N.

д.м.н., зав. отделом мультифокального атеросклероза НИИ КПССЗ 

rus_gayf@mail.ruАрхиповО. Г.ArhipovO. G.

к.м.н., врач ультразвуковой диагностики Центра реабилитации «Топаз»

rus_gayf@mail.ruНаучно-исследовательский институт комплексных проблем сердечно-сосудистых заболеваний. 650002, Кемерово, Сосновый бульвар, 6РоссияResearch Institute of Complex Problems of Cardiovascular Diseases. Sosnovii bulvar 6, Kemerovo, 650002 RussiaRussian FederationЦентр реабилитации «Топаз». 652840, Кемеровская обл., г. Мыски, ул. Лесхозная, 1РоссияCenter of Rehabilitation “Topaz”. Leshoznaja ul. 1, Myski, 652840 RussiaRussian Federation201630062016123277284Copyright © Gajfulin R.A., Sumin A.N., Arhipov O.G., 20162016Гайфулин Р.А., Сумин А.Н., Архипов О.Г.Gajfulin R.A., Sumin A.N., Arhipov O.G.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.rpcardio.online/jour/article/view/1269Aim

Aim. To study the parameters of diastolic function of the right ventricle (RV) in patients with ischemic heart disease (IHD) in different age groups. Material and methods. Patients (n=678) with IHD aged 38 to 85 years were included into the study. They underwent echocardiography with assessment of RV diastolic function. The following parameters were assessed: rate of early and late diastolic RV filling (Et and At), rate of early and late diastolic motion of the ring of the tricuspid valve (e't and a't), the propagation velocity of RV early filling flow (Vpt). All patients were divided into 2 groups: 1st one - patients up to 60 years old (n=282) and the 2nd group - patients 60 years and older (n=396). Results. In IHD patients RV diastolic dysfunction was detected more often in older age group (34.3%) than in group of patients younger than 60 years (22.3%, p=0.008). The next findings were found in the 2nd group: increase in At; reduction in Et/At ratio and e't/a't, as well as higher levels of systolic and mean pulmonary arterial pressure and the greater the thickness of the RV wall. The following parameters of diastolic RV function correlated with age: At (p=0.004); Et/At (p=0.001); Vpt (p=0.002) and e't/a't ratio (p=0.004). Conclusion. The results should be used in assessment of diastolic RV function in patients of different age groups.

Цель. Изучить показатели диастолической функции правого желудочка (ПЖ) у больных ишемической болезнью сердца (ИБС) в разных возрастных группах. Материал и методы. Включено 678 больных ИБС в возрасте от 38 до 85 лет, которым проведено эхокардиографическое исследование с оценкой диастолической функции ПЖ: скорости раннего и позднего диастолического наполнения ПЖ (Ет и Ат), скорости раннего и позднего диастолических движений кольца трикуспидального клапана (e’t и a’t), скорость распространения раннего потока наполнения ПЖ (СРТП). Выделены 2 группы: 1-я – больные до 60 лет (n=282) и 2-я – больные 60 лет и старше (n=396). Результаты. У больных ИБС диастолическая дисфункция ПЖ чаще выявляется в старших возрастных группах (34,3%), чем у лиц моложе 60 лет (22,3%, р=0,008). Во 2-й группе отмечено повышение Ат; снижение отношений Ет/Ат и e’t/a’t, а также выше уровень систолического и среднего давления в легочной артерии и больше толщина стенки ПЖ. С возрастом коррелировали следующие показатели диастолической функции ПЖ: Ат (р=0,004); Ет/Ат (р=0,001); СРТП (р=0,002) и отношение e’t/a’t (р=0,004). Заключение. Полученные результаты целесообразно использовать при оценке диастолической функции ПЖ у больных разных возрастных групп.

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The authors declare that there are no conflicts of interest present.