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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">rpcardio</journal-id><journal-title-group><journal-title xml:lang="en">Rational Pharmacotherapy in Cardiology</journal-title><trans-title-group xml:lang="ru"><trans-title>Рациональная Фармакотерапия в Кардиологии</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1819-6446</issn><issn pub-type="epub">2225-3653</issn><publisher><publisher-name>«SILICEA-POLIGRAF» LLC</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.20996/1819-6446-2016-12-4-366-375</article-id><article-id custom-type="elpub" pub-id-type="custom">rpcardio-1289</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL STUDIES</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ ИССЛЕДОВАНИЯ</subject></subj-group></article-categories><title-group><article-title>Comparative Analysis of All-cause and Cardiovascular Mortality in Moscow and Irkutsk</article-title><trans-title-group xml:lang="ru"><trans-title>СРАВНИТЕЛЬНЫЙ АНАЛИЗ ОБЩЕЙ И СЕРДЕЧНО-СОСУДИСТОЙ СМЕРТНОСТИ НАСЕЛЕНИЯ В МОСКВЕ И ИРКУТСКЕ</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Белялов</surname><given-names>Ф. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Belyalov</surname><given-names>F. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>д.м.н., профессор кафедры геронтологии и гериатрии,</p><p>664079, Иркутск, микрорайон Юбилейный, 100</p></bio><bio xml:lang="en"><p>MD, PhD, Professor of Chair of gerontology and geriatrics, </p><p>Mikrorajon Yubilejnyj 100, Irkutsk, 664079</p></bio><email xlink:type="simple">fbelyalov@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Самородская</surname><given-names>И. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Samorodskaya</surname><given-names>I. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>д.м.н., профессор, руководитель лаборатории демографических аспектов здоровья населения,</p><p>101990, Москва, Петроверигский пер., 10</p></bio><bio xml:lang="en"><p>MD, PhD, Professor, Head of Laboratory of demographic aspects of population health,</p><p>Petroverigsky per., 10, Moscow, 101990</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Погодаева</surname><given-names>С. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Pogodaeva</surname><given-names>S. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>зам. начальника отдела по организации медицинской и лекарственной помощи по г. Иркутску,</p><p>664003, Иркутск, ул. Карла Маркса, 29</p></bio><bio xml:lang="en"><p>MD, Deputy Director of Department for Medical and Pharmaceutical Care Organization for Irkutsk city,</p><p>Karla Marxa ul. 29, Irkutsk, 664003</p></bio><xref ref-type="aff" rid="aff-3"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Иркутская государственная медицинская академия последипломного образования</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Irkutsk State Medical Academy of Postgraduate Education</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Государственный научно-исследовательский центр профилактической медицины</institution><country>Россия</country></aff><aff xml:lang="en"><institution>State Research Center for Preventive Medicine</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>Министерство здравоохранения Иркутской области</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Health Ministry of Irkutsk Region</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2016</year></pub-date><pub-date pub-type="epub"><day>07</day><month>09</month><year>2016</year></pub-date><volume>12</volume><issue>4</issue><fpage>366</fpage><lpage>375</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Belyalov F.I., Samorodskaya I.V., Pogodaeva S.V., 2016</copyright-statement><copyright-year>2016</copyright-year><copyright-holder xml:lang="ru">Белялов Ф.И., Самородская И.В., Погодаева С.В.</copyright-holder><copyright-holder xml:lang="en">Belyalov F.I., Samorodskaya I.V., Pogodaeva S.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.rpcardio.online/jour/article/view/1289">https://www.rpcardio.online/jour/article/view/1289</self-uri><abstract><sec><title>Aim</title><p>Aim. To study standardized all-cause mortality and cardiovascular mortality (or deaths due to diseases of the circulatory system) in Irkutsk and Moscow including assessment in gender and age subgroups.</p></sec><sec><title>Material and methods</title><p>Material and methods. To compare mortality in the two cities data of Federal State Statistics Service were used with calculation of coefficients of mortality adjusted for European age pattern.</p></sec><sec><title>Results</title><p>Results: Age-standardized indices of mortality per 100,000 of population were significantly lowerin Moscow as compared to Irkutsk in the entire sample (697.6 vs 1157.8; p&lt;0.00001), in men (904.0 vs 1364.3; p&lt;0.00001) and in women (535.1 vs 822.7; p&lt;0.00001), and also in all age subgroups above 25 years. Cardiovascular diseases were dominated in the mortality patterns of the compared cities: 47% in Irkutsk, 64% in Moscow. Chronic forms of ischemic heart disease (47.9% in Irkutsk and 45.9% in Moscow) and cerebrovascular diseases (15.9% in Irkutsk and 16.7% in Moscow) were prevalent. There were significant distinctions in death rates encoded in such headings as: “Otherforms of acute ischemic heart disease”, “Atherosclerotic heart disease”, “Cerebral atherosclerosis”, “Hypertensive encephalopathy”, and “Unspecified cardiomyopathy”.</p></sec><sec><title>Conclusion</title><p>Conclusion. Irkutsk had higher standardized coefficients of all-cause and cardiovascular mortality as compared to Moscow in the total population, in men and in women and in majority of age subgroups. This can be explained by economic, social and climatic factors.</p></sec></abstract><trans-abstract xml:lang="ru"><sec><title>Цель</title><p>Цель. Изучить стандартизированную общую смертность и смертность от болезней системы кровообращения среди населения Иркутска и Москвы, включая оценку в гендерных и возрастных группах.</p></sec><sec><title>Материал и методы</title><p>Материал и методы. Для сопоставления смертности двух городов использовали данные Федеральной службыгосударственной статистики с расчетом стандартизированных по европейской возрастной структуре коэффициентов смертности.</p></sec><sec><title>Результаты</title><p>Результаты. Стандартизированные по возрасту показатели смертности населения на 100.000 населения существенно ниже в Москве по сравнению с Иркутском во всей выборке (697,6 против 1157,8; p&lt;0,00001), у мужчин (904,0 против 1364,3; p&lt;0,00001) и женщин (535,1 против 822,7; p&lt;0,00001), а также во всех возрастных группах, начиная с 25 лет. В структуре смертности сравниваемых городов доминируют болезни системы кровообращения: 47% в Иркутске, 64% в Москве. Среди последних преобладают хронические формыишемической болезни сердца (47,9% в Иркутске; 45,9% в Москве) и цереброваскулярных болезней (15,9% в Иркутске; 16,7% в Москве). Имеют место существенные различия в частоте смертей, кодируемых в рубриках «Другие формыострой ишемической болезни сердца», «Атеросклеротическая болезнь сердца», «Церебральный атеросклероз», «Гипертоническая энцефалопатия», «Неуточненная кардиомиопатия».</p></sec><sec><title>Заключение</title><p>Заключение. Установлены более высокие общие и сердечно-сосудистые стандартизированные коэффициенты смертности населения Иркутска по сравнению с Москвой среди всего населения, мужчин и женщин, а также в большинстве возрастных подгрупп, что может быть связано с экономическими, социальными и климатическими факторами.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>общая смертность</kwd><kwd>сердечно-сосудистая смертность</kwd><kwd>городское население</kwd></kwd-group><kwd-group xml:lang="en"><kwd>all-cause mortality</kwd><kwd>cardiovascular mortality</kwd><kwd>city populatio</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Roth G.A., Huffman M.D., Moran A.E., et al. Global and Regional Patterns in Cardiovascular Mortality From 1990 to 2013. Circulation 2015;132:1667-78.</mixed-citation><mixed-citation xml:lang="en">Roth G.A., Huffman M.D., Moran A.E., et al. 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