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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">rpcardio</journal-id><journal-title-group><journal-title xml:lang="en">Rational Pharmacotherapy in Cardiology</journal-title><trans-title-group xml:lang="ru"><trans-title>Рациональная Фармакотерапия в Кардиологии</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1819-6446</issn><issn pub-type="epub">2225-3653</issn><publisher><publisher-name>«SILICEA-POLIGRAF» LLC</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.20996/1819-6446-2017-13-1-107-115</article-id><article-id custom-type="elpub" pub-id-type="custom">rpcardio-1424</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>POINT OF VIEW</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ТОЧКА ЗРЕНИЯ</subject></subj-group></article-categories><title-group><article-title>MONITORING OF THE EFFECTIVENESS OF ANTIPLATELET THERAPY IN CARDIOLOGY PRACTICE</article-title><trans-title-group xml:lang="ru"><trans-title>ПРОБЛЕМА КОНТРОЛЯ ЭФФЕКТИВНОСТИ АНТИТРОМБОЦИТАРНОЙ ТЕРАПИИ В КАРДИОЛОГИЧЕСКОЙ ПРАКТИКЕ</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Пучиньян</surname><given-names>Н. ф.</given-names></name><name name-style="western" xml:lang="en"><surname>Puchinian</surname><given-names>N. F.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Пучиньян Никита Филиппович – кандидат медицинских наук,  научный сотрудник отдела атеросклероза и ХИБС, НИИ кардиологии.</p><p>410012, Саратов, ул. Большая Казачья, 112</p></bio><bio xml:lang="en"><p>Nikita F. Puchinian – MD, PhD, Researcher,  Department of Atherosclerosis and Chronic Ischemic Heart Disease, Research Institute of Cardiology.</p></bio><email xlink:type="simple">puchin@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Фурман</surname><given-names>Н. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Furman</surname><given-names>N. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Фурман Николай Викторович – кандидат медицинских наук,  заведующий отделом неотложной кардиологии, НИИ кардиологии.</p></bio><bio xml:lang="en"><p>Nikolai V. Furman – MD, PhD, Head of Department of Emergency Cardiology, Research Institute of Cardiology.</p><p>Bolshaya Kazachia ul. 112, Saratov, 410012</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Малинова</surname><given-names>Л. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Malinova</surname><given-names>L. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Малинова Лидия Игоревна – доктор медицинских наук, заведующий отделом атеросклероза и ХИБС, НИИ кардиологии.</p><p>410012, Саратов, ул. Большая Казачья, 112</p></bio><bio xml:lang="en"><p>Lidiya I. Malinova – MD, PhD, Head of Department of Atherosclerosis and Chronic Ischemic Heart Disease, Research Institute of Cardiology.</p><p>Bolshaya Kazachia ul. 112, Saratov, 410012</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Долотовская</surname><given-names>П. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Dolotovskaya</surname><given-names>P. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Долотовская Полина Владимировна – кандидат медицинских наук,  научный сотрудник отдела неотложной кардиологии, НИИ кардиологии.</p><p>410012, Саратов, ул. Большая Казачья, 112</p></bio><bio xml:lang="en"><p>Polina V. Dolotovskaya – MD, PhD, Researcher,  Department of Emergency Cardiology, Research Institute of Cardiology.</p><p>Bolshaya Kazachia ul. 112, Saratov, 410012</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Саратовский государственный медицинский университет имени В.И. Разумовского</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Saratov State Medical University named after V. I. Razumovsky</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2017</year></pub-date><pub-date pub-type="epub"><day>04</day><month>03</month><year>2017</year></pub-date><volume>13</volume><issue>1</issue><fpage>107</fpage><lpage>115</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Puchinian N.F., Furman N.V., Malinova L.I., Dolotovskaya P.V., 2017</copyright-statement><copyright-year>2017</copyright-year><copyright-holder xml:lang="ru">Пучиньян Н.ф., Фурман Н.В., Малинова Л.И., Долотовская П.В.</copyright-holder><copyright-holder xml:lang="en">Puchinian N.F., Furman N.V., Malinova L.I., Dolotovskaya P.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.rpcardio.online/jour/article/view/1424">https://www.rpcardio.online/jour/article/view/1424</self-uri><abstract><p>Monitoring of the effectiveness of drug therapy is one of the most debated issues in everyday clinical practice. The emergence of new drugs,  methods of analysis, standards, management protocols, and clinical guidelines increases the information load on practitioners and requires a significant investment of time and efforts for self-education. The purpose of the review is to help practitioners in summary form to obtain the necessary information on the issue of control of antiplatelet therapy. The review brings together data  from current  clinical recommendations on antiplatelet therapy in patients with ischemic heart disease, gives information of existing approaches to control of antiplatelet therapy specified in the guidelines and the consensuses of experts. It presents information on the most common modern methods of monitoring of the antiplatelet therapy effectiveness.</p></abstract><trans-abstract xml:lang="ru"><p>Контроль эффективности лекарственной терапии  является одной  из наиболее обсуждаемых проблем в повседневной клинической работе. Появление новых препаратов, методов анализа, стандартов, протоколов ведения, и клинических рекомендаций повышает  информационную нагрузку на практикующих  врачей, требует существенных  затрат сил и времени для самообразования. Цель обзора – в краткой форме помочь практикующим врачам получить необходимые сведения по проблеме контроля антитромбоцитарной терапии. В обзоре воедино сведены данные современных клинических рекомендаций по антитромбоцитарной терапии у больных ишемической болезнью сердца, приведены сведения о существующих подходах к контролю антитромбоцитарной терапии, изложенные в клинических рекомендациях и консенсусах специалистов. Представлены сведения о наиболее распространенных современных методах  контроля эффективности антитромбоцитарной терапии.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>ишемическая болезнь сердца</kwd><kwd>антитромбоцитарная терапия</kwd><kwd>аспирин</kwd><kwd>клопидогрел</kwd><kwd>резистентность</kwd><kwd>контроль</kwd></kwd-group><kwd-group xml:lang="en"><kwd>ischemic heart disease</kwd><kwd>antiplatelet therapy</kwd><kwd>aspirin</kwd><kwd>clopidogrel</kwd><kwd>resistance</kwd><kwd>control</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Patrono C., Andreotti F., Arnesen H. et al Antiplatelet Agents for the Treatment and Prevention o8 f Atherothrombosis. Eur Heart J. 2011;32(23):2922-32.</mixed-citation><mixed-citation xml:lang="en">Patrono C., Andreotti F., Arnesen H. et al Antiplatelet Agents for the Treatment and Prevention o8 f Atherothrombosis. 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