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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">rpcardio</journal-id><journal-title-group><journal-title xml:lang="en">Rational Pharmacotherapy in Cardiology</journal-title><trans-title-group xml:lang="ru"><trans-title>Рациональная Фармакотерапия в Кардиологии</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1819-6446</issn><issn pub-type="epub">2225-3653</issn><publisher><publisher-name>«SILICEA-POLIGRAF» LLC</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.20996/1819-6446-2017-13-2-238-247</article-id><article-id custom-type="elpub" pub-id-type="custom">rpcardio-1451</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>INNOVATIVE CARDIOLOGY</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ИННОВАЦИОННАЯ КАРДИОЛОГИЯ</subject></subj-group></article-categories><title-group><article-title>POSSIBILITIES OF ENHANCED EXTERNAL COUNTERPULSATION USING IN CLINICAL PRACTICE</article-title><trans-title-group xml:lang="ru"><trans-title>ВОЗМОЖНОСТИ ПРИМЕНЕНИЯ УСИЛЕННОЙ НАРУЖНОЙ КОНТРПУЛЬСАЦИИ В КЛИНИЧЕСКОЙ ПРАКТИКЕ</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Мамиева</surname><given-names>З. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Mamieva</surname><given-names>Z. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Мамиева Зарина Ахсарбековна – студентка 6 курса, лечебный факультет </p><p>119991, Москва, ул. Трубецкая, 8 стр. 2</p></bio><bio xml:lang="en"><p>Zarina A. Mamieva - 6th Year Student, Medical Faculty </p><p>Trubetskaya ul. 8,Moscow, 119991</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Лишута</surname><given-names>А. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Lishuta</surname><given-names>A. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Лишута Алексей Сергеевич – кандидат медицинских наук, доцент кафедры госпитальной терапии №1 </p><p>119991, Москва, ул. Трубецкая, 8 стр. 2</p></bio><bio xml:lang="en"><p>Alexey S. Lishuta - MD, PhD, Associate Professor, Chair of Hospital Therapy №1 </p><p>Trubetskaya ul. 8,Moscow, 119991</p></bio><email xlink:type="simple">alexeylish@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Беленков</surname><given-names>Ю. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Belenkov</surname><given-names>Yu. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Беленков Юрий Никитич – доктор медицинских наук, профессор, академик РАН, зав. кафедрой госпитальной терапии №1 </p><p>119991, Москва, ул. Трубецкая, 8 стр. 2</p></bio><bio xml:lang="en"><p>Yuri N. Belenkov - MD, PhD, Professor, Academician of the Russian Academy of Sciences, Head of Chair of Hospital Therapy №1 </p><p>Trubetskaya ul. 8,Moscow, 119991</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Привалова</surname><given-names>Е. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Privalova</surname><given-names>E. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Привалова Елена Витальевна – доктор медицинских наук, профессор кафедры госпитальной терапии №1 </p><p>119991, Москва, ул. Трубецкая, 8 стр. 2</p></bio><bio xml:lang="en"><p>Elena V. Privalova - MD, PhD, Professor, Chair of Hospital Therapy №1 №1</p><p>Trubetskaya ul. 8,Moscow, 119991</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Юсупова</surname><given-names>А. О.</given-names></name><name name-style="western" xml:lang="en"><surname>Yusupova</surname><given-names>A. O.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Юсупова Альфия Оскаровна – кандидат медицинских наук, доцент кафедры госпитальной терапии №1 </p><p>119991, Москва, ул. Трубецкая, 8 стр. 2</p></bio><bio xml:lang="en"><p>Alfiya O. Yusupova - MD, PhD, Associate Professor, Chair of Hospital Therapy №1</p><p>Trubetskaya ul. 8,Moscow, 119991</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Рыкова</surname><given-names>С. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Rykova</surname><given-names>S. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Рыкова Светлана Михайловна - кандидат медицинских наук, доцент кафедры клинической фармакологии и фармакотерапии ИПО </p><p>119991, Москва, ул. Трубецкая, 8 стр. 2</p></bio><bio xml:lang="en"><p>Svetlana M. Rykova - MD, PhD, Associate Professor, Chair of Clinical Pharmacology and Pharmacotherapy, Institute of Professional Education </p><p>Trubetskaya ul. 8,Moscow, 119991</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Первый Московский государственный медицинский университет имени И.М. Сеченова</institution><country>Россия</country></aff><aff xml:lang="en"><institution>I.M. Sechenov First Moscow State Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2017</year></pub-date><pub-date pub-type="epub"><day>04</day><month>05</month><year>2017</year></pub-date><volume>13</volume><issue>2</issue><fpage>238</fpage><lpage>247</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Mamieva Z.A., Lishuta A.S., Belenkov Y.N., Privalova E.V., Yusupova A.O., Rykova S.M., 2017</copyright-statement><copyright-year>2017</copyright-year><copyright-holder xml:lang="ru">Мамиева З.А., Лишута А.С., Беленков Ю.Н., Привалова Е.В., Юсупова А.О., Рыкова С.М.</copyright-holder><copyright-holder xml:lang="en">Mamieva Z.A., Lishuta A.S., Belenkov Y.N., Privalova E.V., Yusupova A.O., Rykova S.M.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.rpcardio.online/jour/article/view/1451">https://www.rpcardio.online/jour/article/view/1451</self-uri><abstract><p>Possibilities and prospects for the clinical use of enhanced external counterpulsation (EECP), which has long established itself throughout the world, are discussed in the article. Historical background, as well as the development stages of EECP for the treatment of patients with coronary heart disease (CHD) and chronic heart failure (CHF) are considered. The mechanism of action of the EECP and the main hemodynamic, neurohumoral and tissue effects that justify its use are presented. The effect of EECP on endothelial function and coronary reserve, disorders of which occurs in the majority of cardiovascular diseases, is considered separately. Treatment of patients with CHD, including complicated by CHF, are the most studied indications for EECP using in medical practice. The evidence base for treatment of patients with these disorders by EECP is presented in the article. Prospects for the EECP application in other areas of medicine are also presented.</p></abstract><trans-abstract xml:lang="ru"><p>В статье рассматриваются возможности и перспективы применения в клинической практике такого метода лечения, как усиленная наружная контрпульсация (УНКП), уже давно зарекомендовавшего себя во всем мире. Рассматриваются исторические предпосылки, а также этапы разработки данного метода для лечения пациентов с ишемической болезнью сердца (ИБС) и хронической сердечной недостаточностью (ХСН). Детально разбирается механизм действия УНКП и основные гемодинамические, нейрогуморальные и тканевые эффекты, лежащие в основе применения данного вида лечения. Отдельно рассматривается влияние УНКП на эндотелиальную функцию и коронарный резерв, нарушение которых имеет место при большинстве сердечно-сосудистых заболеваний. Среди наиболее изученных показаний для применения УНКП является лечение пациентов с ИБС, в том числе, осложненной ХСН. В статье представлена доказательная база лечения больных этими нарушениями с использованием УНКП. Также представлены перспективные направления применения этого метода лечения в других направлениях медицины.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>усиленная наружная контрпульсация</kwd><kwd>эндотелиальная функция</kwd><kwd>коронарный резерв</kwd><kwd>ишемическая болезнь сердца</kwd><kwd>хроническая сердечная недостаточность</kwd></kwd-group><kwd-group xml:lang="en"><kwd>enhanced external counterpulsation</kwd><kwd>endothelial function</kwd><kwd>coronary reserve</kwd><kwd>ischemic heart disease</kwd><kwd>chronic heart failure</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Kantrowitz A. Experimental augmentation of coronary flow by retardation of the arterial pressure pulse. Surgery. 1953;34(4):678-87.</mixed-citation><mixed-citation xml:lang="en">Kantrowitz A. 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