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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">rpcardio</journal-id><journal-title-group><journal-title xml:lang="en">Rational Pharmacotherapy in Cardiology</journal-title><trans-title-group xml:lang="ru"><trans-title>Рациональная Фармакотерапия в Кардиологии</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1819-6446</issn><issn pub-type="epub">2225-3653</issn><publisher><publisher-name>«SILICEA-POLIGRAF» LLC</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">rpcardio-1462</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>POINT OF VIEW</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ТОЧКА ЗРЕНИЯ</subject></subj-group></article-categories><title-group><article-title>Drug interactions of non-vitamin K antagonist oral anticoagulants: inside and outside table cells</article-title><trans-title-group xml:lang="ru"><trans-title>Лекарственные взаимодействия новых пероральных антикоагулянтов: внутри и вне ячеек таблицы</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-0831-6320</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Бельдиев</surname><given-names>Сергей Николаевич</given-names></name><name name-style="western" xml:lang="en"><surname>Bel'diev</surname><given-names>Sergey Nikolaevich</given-names></name></name-alternatives><bio xml:lang="ru"><p>Кафедра внутренних болезней факультета дополнительного профессионального образования, доцент, SPIN-код 3313-6347</p></bio><bio xml:lang="en"><p>Faculty of Postgraduate Studies, Chair of Internal Medicine, Associate Professor</p></bio><email xlink:type="simple">sbeldiev@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Медведева</surname><given-names>Ирина Владимировна</given-names></name><name name-style="western" xml:lang="en"><surname>Medvedeva</surname><given-names>Irina Vladimirovna</given-names></name></name-alternatives><bio xml:lang="ru"><p>Кафедра внутренних болезней факультета дополнительного профессионального образования, доцент</p></bio><bio xml:lang="en"><p>Faculty of Postgraduate Studies, Chair of Internal Medicine, Associate Professor</p></bio><email xlink:type="simple">irinavlmed@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Платонов</surname><given-names>Дмитрий Юрьевич</given-names></name><name name-style="western" xml:lang="en"><surname>Platonov</surname><given-names>Dmitry Jur'evich</given-names></name></name-alternatives><bio xml:lang="ru"><p>Кафедра внутренних болезней факультета дополнительного профессионального образования, зав. кафедрой</p></bio><bio xml:lang="en"><p>Faculty of Postgraduate Studies, Chair of Internal Medicine, Associate Professor, Head of Chair of Internal Medicine</p></bio><email xlink:type="simple">diplato64@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Тверской государственный медицинский университет</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Tver State Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2017</year></pub-date><pub-date pub-type="epub"><day>30</day><month>10</month><year>2017</year></pub-date><volume>13</volume><issue>5</issue><elocation-id>1462</elocation-id><permissions><copyright-statement>Copyright &amp;#x00A9; Bel'diev S.N., Medvedeva I.V., Platonov D.J., 2017</copyright-statement><copyright-year>2017</copyright-year><copyright-holder xml:lang="ru">Бельдиев С.Н., Медведева И.В., Платонов Д.Ю.</copyright-holder><copyright-holder xml:lang="en">Bel'diev S.N., Medvedeva I.V., Platonov D.J.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.rpcardio.online/jour/article/view/1462">https://www.rpcardio.online/jour/article/view/1462</self-uri><abstract><p>The opinion is expressed in some domestic publications that rivaroxaban has the most favorable profile of drug interaction in comparison to other non-vitamin K antagonist oral anticoagulants (NOAC). The basis for such judgments is the summary table of drug interaction from the 2015 practical guide of the European Heart Rhythm Association on the use of NOAC in patients with non-valvular atrial fibrillation.</p></abstract><trans-abstract xml:lang="ru"><p>В некоторых отечественных публикациях высказывается мнение о том, что ривароксабан обладает наиболее благоприятным профилем лекарственного взаимодействия по сравнению с другими новыми оральными антикоагулянтами (НОАК). Основой для подобных суждений стала сводная таблица лекарственных взаимодействий НОАК из рекомендаций Европейской ассоциации сердечного ритма 2015 года по применению НОАК у пациентов с неклапанной фибрилляцией предсердий.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>дабигатран</kwd><kwd>апиксабан</kwd><kwd>ривароксабан</kwd><kwd>эдоксабан</kwd><kwd>лекарственные взаимодействия</kwd></kwd-group><kwd-group xml:lang="en"><kwd>dabigatran</kwd><kwd>apixaban</kwd><kwd>rivaroxaban</kwd><kwd>edoxaban</kwd><kwd>drug interactions</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Bunin Y.A., Miklishanskaya S.V. Clinical significance of new oral anticoagulants in the prevention of thromboembolic complications in patients with atrial fibrillation: not all dreams come true. Ration Pharmacother Cardiol. 2016;12(4):465-70. (In Russian) [Бунин Ю.А., Миклишанская С.В. 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