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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">rpcardio</journal-id><journal-title-group><journal-title xml:lang="en">Rational Pharmacotherapy in Cardiology</journal-title><trans-title-group xml:lang="ru"><trans-title>Рациональная Фармакотерапия в Кардиологии</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1819-6446</issn><issn pub-type="epub">2225-3653</issn><publisher><publisher-name>«SILICEA-POLIGRAF» LLC</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.20996/1819-6446-2014-10-1-99-105</article-id><article-id custom-type="elpub" pub-id-type="custom">rpcardio-163</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>CURRENT QUESTIONS OF CLINICAL PHARMACOLOGY</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>АКТУАЛЬНЫЕ  ВОПРОСЫ  КЛИНИЧЕСКОЙ ФАРМАКОЛОГИИ</subject></subj-group></article-categories><title-group><article-title>MAGNESIUM DEFICIENCY AND CARDIOVASCULAR DISEASES: TIME TO ACT</article-title><trans-title-group xml:lang="ru"><trans-title>ДЕФИЦИТ МАГНИЯ И СЕРДЕЧНО-СОСУДИСТЫЕ ЗАБОЛЕВАНИЯ: ВРЕМЯ ДЕЙСТВОВАТЬ</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Трисветова</surname><given-names>Е. Л.</given-names></name><name name-style="western" xml:lang="en"><surname>Trisvetova</surname><given-names>E. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Трисветова Евгения Леонидовна – доктор медицинских наук, профессор, профессор 2-й кафедры внутренних болезней</p></bio><email xlink:type="simple">trisvet-47@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru">Белорусский государственный медицинский университет<country>Беларусь</country></aff><aff xml:lang="en">Belarusian State Medical University<country>Belarus</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2014</year></pub-date><pub-date pub-type="epub"><day>23</day><month>09</month><year>2015</year></pub-date><volume>10</volume><issue>1</issue><fpage>99</fpage><lpage>105</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Trisvetova E.I., 2015</copyright-statement><copyright-year>2015</copyright-year><copyright-holder xml:lang="ru">Трисветова Е.Л.</copyright-holder><copyright-holder xml:lang="en">Trisvetova E.I.</copyright-holder><license license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.rpcardio.online/jour/article/view/163">https://www.rpcardio.online/jour/article/view/163</self-uri><abstract><p>Progression of cardiovascular disease is often caused by a deficiency of magnesium in the human body. Magnesium belongs to the necessary vital macronutrients providing many physiological and pathological reactions and is involved in the constructive, energy, electrolyte metabolism. Correction of magnesium deficiency is realized using magnesium-containing drugs, for example magnesium orotate, having pleiotropic effects due to independent metabolic activity of orotic acid.</p></abstract><trans-abstract xml:lang="ru"><p>Ухудшение течения сердечно-сосудистых заболеваний нередко обусловлено дефицитом магния в организме человека. Магний относится к необходимым жизненно важным макроэлементам, обеспечивающим многие физиологические и патологические реакции, участвует в пластическом, энергетическом, электролитном обмене. Коррекцию дефицита магния проводят магнийсодержащими препаратами, например, оротатом магния, обладающим плейотропными эффектами за счет самостоятельного метаболического действия оротовой кислоты.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>сердечно-сосудистые заболевания</kwd><kwd>дефицит магния</kwd><kwd>оротат магния</kwd></kwd-group><kwd-group xml:lang="en"><kwd>cardiovascular diseases</kwd><kwd>deficiency of magnesium</kwd><kwd>magnesium orotate</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Gromov OA Torshin IY, KV Rudakov, et al. Lack of magnesium a significant risk factor comorbid conditions: results of a large-scale screening of magnesium status in the regions of Russia. Farmateka 2013; (6):116-29. Russian (ГромоваО.А., ТоршинИ.Ю., РудаковК.В., и др. 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Rom J Intern Med 2004; 42(3):491-501.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
