<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.3 20210610//EN" "JATS-journalpublishing1-3.dtd">
<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">rpcardio</journal-id><journal-title-group><journal-title xml:lang="en">Rational Pharmacotherapy in Cardiology</journal-title><trans-title-group xml:lang="ru"><trans-title>Рациональная Фармакотерапия в Кардиологии</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1819-6446</issn><issn pub-type="epub">2225-3653</issn><publisher><publisher-name>«SILICEA-POLIGRAF» LLC</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.20996/1819-6446-2014-10-2-179-183</article-id><article-id custom-type="elpub" pub-id-type="custom">rpcardio-21</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ANALYSIS OF CLINICAL PRACTICE</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>АНАЛИЗ КЛИНИЧЕСКОЙ ПРАКТИКИ</subject></subj-group></article-categories><title-group><article-title>SECONDARY PREVENTION OF STROKE IN PATIENTS WITH NON-VALVULAR ATRIAL FIBRILLATION: THE CLINICIANS’ VIEWPOINT</article-title><trans-title-group xml:lang="ru"><trans-title>ВТОРИЧНАЯ ПРОФИЛАКТИКА ИНСУЛЬТА У ПАЦИЕНТОВ С НЕКЛАПАННОЙ ФОРМОЙ ФИБРИЛЛЯЦИИ ПРЕДСЕРДИЙ С ТОЧКИ ЗРЕНИЯ КЛИНИЦИСТА</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Дроздова</surname><given-names>Е. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Drozdova</surname><given-names>E. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Дроздова Екатерина Александровна – врач невролог отделения ранней реабилитации больных с острыми нарушениями мозгового кровообращения регионального сосудистого центра</p></bio><email xlink:type="simple">hosp13_2nevrol@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Городская клиническая больница №13, Нижний Новгород</institution><country>Россия</country></aff><aff xml:lang="en"><institution>City Clinical Hospital № 13, Nizhny Novgorod</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2014</year></pub-date><pub-date pub-type="epub"><day>19</day><month>09</month><year>2015</year></pub-date><volume>10</volume><issue>2</issue><fpage>179</fpage><lpage>183</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Drozdova E.A., 2015</copyright-statement><copyright-year>2015</copyright-year><copyright-holder xml:lang="ru">Дроздова Е.А.</copyright-holder><copyright-holder xml:lang="en">Drozdova E.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.rpcardio.online/jour/article/view/21">https://www.rpcardio.online/jour/article/view/21</self-uri><abstract><p>Atrial fibrillation is one of the main risk factor of ischemic stroke. Current problems of the management of patients with stroke due to non-valvular atrial fibrillation and secondary stroke prevention in these patients are considered. Data of own author’s observation for patients of this type during 6 months after discharge from the hospital are presented. The problems which patients faced with are analyzed. Comparative assessment of warfarin and dabigatran therapies is given.</p></abstract><trans-abstract xml:lang="ru"><p>Фибрилляция предсердий – один из важнейших факторов риска развития ишемических инсультов. Рассматриваются актуальные проблемы ведения больных с инсультами, возникшими на фоне неклапанной фибрилляции предсердий, в аспекте вторичной профилактики данного грозного осложнения аритмии. Приводятся данные собственного наблюдения за пациентами с указанной патологией в течение 6-ти месяцев после выписки их из стационара. Анализируются проблемы, с которыми столкнулись больные, а также дается сравнительная оценка терапии антагонистом витамина К варфарином и прямым ингибитором тромбина дабигатраном.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>фибрилляция предсердий</kwd><kwd>геморрагические осложнения</kwd><kwd>профилактика инсульта</kwd></kwd-group><kwd-group xml:lang="en"><kwd>atrial fibrillation</kwd><kwd>hemorrhagic complication</kwd><kwd>stroke prevention</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Connolly SJ, Ezekowitz MD, Yusuf S, et al. Dabigatran versus Warfarin in Patients with Atrial Fibrillation. N Engl J Med 2009; 361(12):1139-51.</mixed-citation><mixed-citation xml:lang="en">Connolly SJ, Ezekowitz MD, Yusuf S, et al. Dabigatran versus Warfarin in Patients with Atrial Fibrillation. N Engl J Med 2009; 361(12):1139-51.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Heppell R. M., Berkin К. E., McLenachan J. M. et al. Haemostatic and haemodynamic abnormalities associated with left atrial thrombosis in nonrheumatic atrial fibrillation. Heart 1997; 77: 407-11.</mixed-citation><mixed-citation xml:lang="en">Heppell R. M., Berkin К. E., McLenachan J. M. et al. Haemostatic and haemodynamic abnormalities associated with left atrial thrombosis in nonrheumatic atrial fibrillation. Heart 1997; 77: 407-11.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Psaty B.M., Manolio T.A., Kuller L.H. et al. Incidence of and risk factors for atrial fibrillation in older adults. Circulation 1997; 96: 2455-61.</mixed-citation><mixed-citation xml:lang="en">Psaty B.M., Manolio T.A., Kuller L.H. et al. Incidence of and risk factors for atrial fibrillation in older adults. Circulation 1997; 96: 2455-61.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Risk factors for stroke and efficacy of antithrombotic therapy in atrial fibrillation: analysis of pooled data from five randomized controlled trials. Arch Intern Med 1994; 154: 1449-57.</mixed-citation><mixed-citation xml:lang="en">Risk factors for stroke and efficacy of antithrombotic therapy in atrial fibrillation: analysis of pooled data from five randomized controlled trials. Arch Intern Med 1994; 154: 1449-57.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Sherman DG, Kim SG, Boop BS, et al. Occurrence and Characteristics of Stroke Events in the Atrial Fibrillation Follow-up Investigation of Sinus Rhythm Management (AFFIRM) Study. Arch Intern Med 2005;165:1185-91.</mixed-citation><mixed-citation xml:lang="en">Sherman DG, Kim SG, Boop BS, et al. Occurrence and Characteristics of Stroke Events in the Atrial Fibrillation Follow-up Investigation of Sinus Rhythm Management (AFFIRM) Study. Arch Intern Med 2005;165:1185-91.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Krahn A. D., Manfreda J., Tate R. B. et al. The Natural history of atrial fibrillation: incidence, risk factors, and prognosis in the Manitoba FollowUp Study. Am J Med 1995; 98: 476-84.</mixed-citation><mixed-citation xml:lang="en">Krahn A. D., Manfreda J., Tate R. B. et al. The Natural history of atrial fibrillation: incidence, risk factors, and prognosis in the Manitoba FollowUp Study. Am J Med 1995; 98: 476-84.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Wolf P. A., Abbott R. D., Kannel W. B. Atrial fibrillation as an independentrisk factorfor stroke: the Framingham Study. Stroke 1991; 22: 983-8.</mixed-citation><mixed-citation xml:lang="en">Wolf P. A., Abbott R. D., Kannel W. B. Atrial fibrillation as an independentrisk factorfor stroke: the Framingham Study. Stroke 1991; 22: 983-8.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
