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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">rpcardio</journal-id><journal-title-group><journal-title xml:lang="en">Rational Pharmacotherapy in Cardiology</journal-title><trans-title-group xml:lang="ru"><trans-title>Рациональная Фармакотерапия в Кардиологии</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1819-6446</issn><issn pub-type="epub">2225-3653</issn><publisher><publisher-name>«SILICEA-POLIGRAF» LLC</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.20996/1819-6446-2020-02-05</article-id><article-id custom-type="elpub" pub-id-type="custom">rpcardio-2109</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>NOTES FROM PRACTICE</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>КЛИНИЧЕСКИЙ ОПЫТ</subject></subj-group></article-categories><title-group><article-title>Thoracalgia in a Patient with Determined Coronary Heart Disease. Is there Always a Relapse of Angina Pectoris?</article-title><trans-title-group xml:lang="ru"><trans-title>Боли за грудиной у пациента с известной ишемической болезнью сердца. Всегда ли рецидив стенокардии?</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Драпкина</surname><given-names>О. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Drapkina</surname><given-names>O. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Драпкина Оксана Михайловна – доктор медицинских наук, профессор, член корреспондент РАН, директор НМИЦ ТПМ</p><p>101990, Москва, Петроверигский пер., 10 </p></bio><bio xml:lang="en"><p>Oxana M. Drapkina – MD, PhD, Professor, Corresponding Member of the Russian Academy of Sciences, Director, National Medical Research Center for Therapy and Preventive Medicine</p><p>Petroverigsky per. 10, Moscow, 101990 </p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Зейнапур</surname><given-names>А. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Zeynapur</surname><given-names>A. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Зейнапур Аида Али-Агаевна – врач-кардиолог, кандидат медицинских наук, заведующий приемным отделением</p><p>101990, Москва, Петроверигский пер., 10 </p></bio><bio xml:lang="en"><p>Aida A. Zeynapur – MD, PhD, Head of Admission Department</p><p>Petroverigsky per. 10, Moscow, 101990 </p></bio><email xlink:type="simple">AZeynapur@gnicpm.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Клевина</surname><given-names>А. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Klevina</surname><given-names>A. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Клевина Алина Сергеевна – врач-кардиолог приемного отделения</p><p>101990, Москва, Петроверигский пер., 10 </p></bio><bio xml:lang="en"><p>Alina S. Klevina – MD, Cardiologist, Admission Department</p><p>Petroverigsky per. 10, Moscow, 101990 </p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Васильева</surname><given-names>О. Б.</given-names></name><name name-style="western" xml:lang="en"><surname>Vasileva</surname><given-names>O. B.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Васильева Ольга Борисовна – врач-кардиолог приемного отделения</p><p>101990, Москва, Петроверигский пер., 10 </p></bio><bio xml:lang="en"><p>Olga B. Vasileva – MD, Cardiologist, Admission Department</p><p>Petroverigsky per. 10, Moscow, 101990 </p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Национальный медицинский исследовательский центр профилактической медицины</institution><country>Россия</country></aff><aff xml:lang="en"><institution>National Medical Research Center for Preventive Medicine</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2020</year></pub-date><pub-date pub-type="epub"><day>17</day><month>02</month><year>2020</year></pub-date><volume>16</volume><issue>1</issue><fpage>46</fpage><lpage>50</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Drapkina O.M., Zeynapur A.A., Klevina A.S., Vasileva O.B., 2020</copyright-statement><copyright-year>2020</copyright-year><copyright-holder xml:lang="ru">Драпкина О.М., Зейнапур А.А., Клевина А.С., Васильева О.Б.</copyright-holder><copyright-holder xml:lang="en">Drapkina O.M., Zeynapur A.A., Klevina A.S., Vasileva O.B.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.rpcardio.online/jour/article/view/2109">https://www.rpcardio.online/jour/article/view/2109</self-uri><abstract><p>This article presents a clinical case of a 62-year-old man with a long history of coronary heart disease and smoking, whose main complaint upon admission to the hospital was voice hoarseness and atypical pain syndrome in the chest. During a preliminary medical examination, attention was paid to the clinical picture, atypical for a coronary heart disease – voice hoarseness was identified as a manifestation of the recurrent nerve compression, or cardio-vocal syndrome. Given the lack of connection between the chest pain and physical exertion, a high index of a smoking person as well as signs of the recurrent nerve compression syndrome, a multi-spiral computer tomography with contrasting of the chest organs was performed (in line with official recommendations of the Russian Associations of Oncologists and Otolaryngologists). The results revealed a proliferative lesion of the mediastinum and multiple focal lesions of both lungs. A subsequent thoracoscopy and biopsy confirmed the mediastinal form of a lung cancer. Promptly initiated poly-chemotherapy allowed stabilizing the patient’s condition and significantly improving his prospects. In this context, the article discusses the complexity of a timely diagnosis of a primary lung cancer and emphasizes the need to focus on specific and unique features of the disease course as well as on a broader clinical picture. Tactics of a multidisciplinary approach allows making a diagnosis in a timely manner, significantly improving the effectiveness of therapy and patient’s survival prognosis.</p></abstract><trans-abstract xml:lang="ru"><p>В данной статье представлен клинический случай: мужчина 62 года с известным анамнезом ишемической болезни сердца и длительным стажем табакокурения, обратившегося с жалобами на осиплость голоса и нетипичный болевой синдром в грудной клетке. В ходе первоначального осмотра было обращено внимание на клиническую картину, нетипичную для ишемической болезни сердца: голосовые изменения были расценены как проявление кардиовокального синдрома. С учетом отсутствия связи болей в грудной клетке с физическим напряжением, высокого индекса курящего человека и клиники синдрома сдавления возвратного нерва, согласно рекомендациям ассоциации онкологов и ассоциации отоларингологов России была выполнена мультиспиральная компьютерная томография с контрастированием органов грудной клетки. По данным исследования было выявлено пролиферативное поражение средостения и множественное очаговое поражение обоих легких. Последующая торакоскопия с биопсией подтвердила медиастенальную форму рака легких. Начатая полихимиотерапия позволила стабилизировать клиническое состояние и улучшить прогноз. В статье обсуждаются сложности своевременной диагностики первичного рака легких. Подчеркивается необходимость концентрации внимания на особенностях течения заболевания и на глубоком анализе клинической картины. Тактика мультидисциплинарного подхода позволяет своевременно поставить диагноз, кардинально улучшить эффективность терапии и прогноз выживаемости пациента.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>загрудинные боли</kwd><kwd>осиплость голоса</kwd><kwd>синдром сдавления возвратного нерва (кардиовокальный синдром)</kwd><kwd>медиастенальная форма рака легких</kwd></kwd-group><kwd-group xml:lang="en"><kwd>chest pain</kwd><kwd>voice hoarseness</kwd><kwd>nerve compression of the recurrent nerve (cardiovocal syndrome)</kwd><kwd>mediastinal stage of lung cancer</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Рак легкого. Клинические рекомендации, 2018. Ассоциация онкологов России. Российское общество клинической онкологии. [цитировано 11.12.2019]. 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