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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">rpcardio</journal-id><journal-title-group><journal-title xml:lang="en">Rational Pharmacotherapy in Cardiology</journal-title><trans-title-group xml:lang="ru"><trans-title>Рациональная Фармакотерапия в Кардиологии</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1819-6446</issn><issn pub-type="epub">2225-3653</issn><publisher><publisher-name>«SILICEA-POLIGRAF» LLC</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.20996/1819-6446-2020-10-21</article-id><article-id custom-type="elpub" pub-id-type="custom">rpcardio-2312</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>POINT OF VIEW</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ТОЧКА ЗРЕНИЯ</subject></subj-group></article-categories><title-group><article-title>Atrial Fibrillation: the Association with Physical Activity and the Effects of Cardiac Rehabilitation</article-title><trans-title-group xml:lang="ru"><trans-title>Фибрилляция предсердий: связь с физической активностью и эффекты кардиореабилитации</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Бубнова</surname><given-names>М. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Bubnova</surname><given-names>M. G.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Бубнова Марина Геннадьевна – доктор медицинских наук, профессор, руководитель отдела реабилитации и вторичной профилактики сердечно-сосудистых заболеваний</p><p>101990, Москва, Петроверигский пер., 10 стр. 3 </p></bio><bio xml:lang="en"><p>Marina G. Bubnova – MD, PhD, Professor, Head of Department of Rehabilitation and Secondary Prevention for Cardiovascular Disease</p><p>Petroverigsky per. 10, Moscow, 101990 </p></bio><email xlink:type="simple">mbubnova@gnicpm.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Аронов</surname><given-names>Д. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Aronov</surname><given-names>D. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Аронов Давид Меерович – доктор медицинских наук профессор, главный научный сотрудник, отдел реабилитации и вторичной профилактики сердечно-сосудистых заболеваний</p><p>101990, Москва, Петроверигский пер., 10 стр. 3 </p></bio><bio xml:lang="en"><p>David M. Aronov – MD, PhD, Professor, Chief Researcher, Department of Rehabilitation and Secondary Prevention for Cardiovascular Disease</p><p>Petroverigsky per. 10, Moscow, 101990 </p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Национальный медицинский исследовательский центр терапии и профилактической медицины</institution><country>Россия</country></aff><aff xml:lang="en"><institution>National Medical Research Center for Therapy and Preventive Medicine</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2020</year></pub-date><pub-date pub-type="epub"><day>04</day><month>11</month><year>2020</year></pub-date><volume>16</volume><issue>5</issue><fpage>804</fpage><lpage>814</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Bubnova M.G., Aronov D.M., 2020</copyright-statement><copyright-year>2020</copyright-year><copyright-holder xml:lang="ru">Бубнова М.Г., Аронов Д.М.</copyright-holder><copyright-holder xml:lang="en">Bubnova M.G., Aronov D.M.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.rpcardio.online/jour/article/view/2312">https://www.rpcardio.online/jour/article/view/2312</self-uri><abstract><p>The purpose of this review was to present modern studies that examine the relationship of physical activity and risk of atrial fibrillation (AF) development and the impact of cardiac rehabilitation programs in patients with all forms of AF. Data of 52 Russian and foreign scientific sources published in 1998- 2020 were presented. In our study, 48 patients with paroxysmal AF after radiofrequency ablation (RFA) were randomly assigned to a physical rehabilitation/standard therapy or control (standard therapy) group. Aerobic physical training was conducted for 6 months 3 times a week. AF is one of the most common cardiac arrhythmias. Despite modern advances, results of treatment of this disease are far from optimal. Many problems of patients with AF can be addressed through enrolment in multidisciplinary cardiac rehabilitation programs. But this question remains open. This is mainly due to the complexity of selection of physical rehabilitation program for patients with AF. It is known that physical activity can trigger an episode of AF. In the following review article, the approaches to functional capacity assessment of patient with AF are described, recommendations for prescribing safe exercise training to achieve a therapeutic effect are presented. Various aspects of the effects of physical rehabilitation are discussed, including its impact on cardiovascular risk factors, influence on atrial remodeling processes and associated biomarkers, prevention of AF progression and occurrence of cardiovascular complications. Results of our own research indicate effectiveness of physical training in patients with AF after RFA: increase in exercise duration by 18.6% (p&lt;0.001) and load by 24.8% (p&lt;0.01) during exercise test, increase in level of everyday physical activity by 23.8% (p=0.001); left atrium dimensions remain stable comparing with control group. That was combined with a decrease of post ablation atrial arrhythmias: after 6 months, they were registered in 4.5% of trained patients vs 17.4% of control group patients (p&lt;0.01). Steady growth in the number of patients with AF and catheter ablation procedures around the world dictates the need for organization of multi-purpose medical rehabilitation.</p></abstract><trans-abstract xml:lang="ru"><p>Целью данного обзора было осветить современные представления о взаимосвязи физической активности с риском развития фибрилляции предсердий (ФП) и важности кардиореабилитационных программ у больных с разными формами ФП. Представлены данные 52 научных источников, опубликованных в российской и зарубежной печати в 1998-2020 гг. В собственном исследовании 48 пациентов с пароксизмальной формой ФП после радиочастотной аблации (РЧА) были рандомизированы в группу физической реабилитации/стандартной терапии или контроля (стандартной терапии). Аэробные физические тренировки проходили 3 р/нед в течение 6 мес. ФП – одно из часто встречающихся нарушений ритма сердца. Несмотря на современные достижения, лечение данного заболевания далеко от оптимальных результатов. Многие проблемы больных с ФП можно решать через мультидисциплинарные программы кардиореабилитации, но этот вопрос остается открытым. Во многом это обусловлено сложностью составления программ физической реабилитации при ФП: известно, что физические нагрузки могут провоцировать приступ ФП. В обзоре описаны подходы к оценке физической работоспособности (ФРС) больного с ФП, представлены рекомендации по выбору безопасных тренирующих нагрузок, позволяющих достигать лечебного эффекта. Обсуждаются разные аспекты влияния физической реабилитации, включая кардиоваскулярные факторы риска, процессы ремоделирования предсердий и связанные с ними биомаркеры, предупреждение прогрессирования ФП и развития сердечно-сосудистых осложнений. Результаты собственного исследования свидетельствуют об эффективном влиянии физических тренировок у больных с ФП после РЧА: увеличении длительности нагрузки на 18,6% (р&lt;0,001) и мощности нагрузки на 24,8% (р&lt;0,01) после нагрузочного теста, уровня повседневной физической активности на 23,8% (p=0,001) при стабильности размеров левого предсердия, в отличие от группы контроля. Это сочеталось с уменьшением количества регистрируемых постаблационных предсердных аритмий: через 6 мес они регистрировались у 4,5% тренировавшихся больных против 17,4% больных из группы сравнения (р&lt;0,01). Неуклонный рост количества пациентов с ФП и процедур катетерной аблации во всем мире диктует необходимость организации комплексной медицинской реабилитации.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>фибрилляция предсердий</kwd><kwd>катетерная аблация</kwd><kwd>физическая активность</kwd><kwd>физическая тренировка</kwd><kwd>кардиореабилитация</kwd></kwd-group><kwd-group xml:lang="en"><kwd>atrial fibrillation</kwd><kwd>catheter ablation</kwd><kwd>physical activity</kwd><kwd>exercise training</kwd><kwd>cardiac rehabilitation</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Kirchhof P., Benussi S., Kotecha D., et al. 2016 ESC Guidelines for the management of atrial fibrillation developed in collaboration with EACTS. Eur Heart J. 2016;37(38):2893-962. 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