rpcardioRational Pharmacotherapy in CardiologyРациональная Фармакотерапия в Кардиологии1819-64462225-3653«SILICEA-POLIGRAF» LLC10.20996/1819-6446-2021-12-04rpcardio-2635Research ArticlePOINT OF VIEWТОЧКА ЗРЕНИЯHyperuricemia: Features of the DietГиперурикемия: особенности рациона питанияhttps://orcid.org/0000-0001-9786-4144ШвабскаяО. Б.ShvabskaiaO. B.

Швабская Ольга Борисовна.

Москва.

eLibrary  SPIN  1193-2792

Olga B. Shvabskaia.

Moscow.

eLibrary  SPIN  1193-2792

oshvabskaya@gnicpm.ruhttps://orcid.org/0000-0002-7989-6844ИзмайловаО. В.IzmailovaO. V.

Измайлова Ольга Викторовна.

Москва.

eLibrary  SPIN  5597-8420

Olga V. Izmailova.

Moscow.

eLibrary  SPIN  5597-8420

https://orcid.org/0000-0002-8604-712XКарамноваН. С.KaramnovaN. S.

Карамнова Наталья Станиславовна.

Москва.

eLibrary SPIN 2878-3016

Natalia S. Karamnova.

Moscow.

eLibrary SPIN 2878-3016

https://orcid.org/0000-0002-4453-8430ДрапкинаО. М.DrapkinaO. M.

Драпкина Оксана Михайловна.

Москва.

eLibrary  SPIN  4456-1297

Oxana M. Drapkina.

Moscow.

eLibrary  SPIN  4456-1297

Национальный медицинский исследовательский центр терапии и профилактической медициныРоссияNational Medical Research Center for Therapy and Preventive MedicineRussian Federation202112012022176889899Copyright © Shvabskaia O.B., Izmailova O.V., Karamnova N.S., Drapkina O.M., 20222022Швабская О.Б., Измайлова О.В., Карамнова Н.С., Драпкина О.М.Shvabskaia O.B., Izmailova O.V., Karamnova N.S., Drapkina O.M.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.rpcardio.online/jour/article/view/2635

The association of hyperuricemia (HU) with cardiovascular disease (CVD), diabetes, metabolic syndrome, and kidney disease has been demonstrated in numerous studies. НU is the main pathogenetic factor in the development of gout and is associated with an increase in overall and cardiovascular mortality. НU is included in the list of factors determining cardiovascular risk. According to epidemiological studies, there is a high prevalence of HU in the world and its increase in recent decades. A number of factors have been identified that contribute to the increased risk of НU. Non-modifiable factors include gender, age, genetic factors, and modifiable factors include diet and lifestyle. Nutritional unbalances, increased life expectancy, increased prevalence of obesity, and increased use of drugs (especially diuretics) are seen as contributing factors to the rise in НU. The review was carried out to summarize the available information on the effect of dietary habits, individual foods and nutrients on serum uric acid (SUA) levels and the risk of developing HU. The review presents the results of scientific studies demonstrating the relationship of НU with the consumption of foods rich in purines (offal, red meat, fish, seafood, legumes), alcohol consumption, drinks sweetened with fructose, coffee, dairy products, vegetables and fruits. Diet correction is an important and necessary step in the prevention and treatment of НU. The article reviews the basic principles of dietary management in HU and provides dietary recommendations for patients. For effective prevention and treatment of НU, a mandatory correction of the diet is required.

Связь гиперурикемии (ГУ) с сердечно-сосудистыми заболеваниями (ССЗ), сахарным диабетом, метаболическим синдромом, болезнями почек продемонстрирована в многочисленных исследованиях. ГУ – основной патогенетический фактор развития подагры, ассоциирована с повышением общей и сердечно-сосудистой смертности. ГУ включена в перечень факторов, определяющих сердечно-сосудистый риск. По данным эпидемиологических исследований отмечается высокая распространенность ГУ в мире и ее рост в последние десятилетия. Выявлен целый ряд факторов, способствующих повышению риска ГУ. К немодифицируемым факторам относятся пол, возраст, генетические факторы, к модифицируемым – характер питания и образ жизни. Дисбаланс в характере питания, увеличение продолжительности жизни, рост распространенности ожирения, увеличение использования лекарственных препаратов (особенно диуретиков) рассматриваются как факторы, способствующие росту ГУ. Обзор выполнен с целью обобщения имеющихся сведений о влиянии характера питания, отдельных продуктов и нутриентов на уровень мочевой кислоты (МК) в сыворотке крови и риск развития ГУ. В обзоре представлены результаты научных исследований, демонстрирующих связь ГУ с потреблением продуктов, богатых пуринами (субпродуктов, красного мяса, рыбы, морепродуктов, бобовых), потреблением алкоголя, подслащенных фруктозой напитков, кофе, молочных продуктов, овощей и фруктов. Коррекция питания – важный и необходимый шаг для профилактики и лечения ГУ. В обзоре рассмотрены основные принципы диетотерапии при ГУ и представлены рекомендации по питанию для пациентов. Для эффективной профилактики и лечения ГУ необходима обязательная коррекция рациона.

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The authors declare that there are no conflicts of interest present.