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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">rpcardio</journal-id><journal-title-group><journal-title xml:lang="en">Rational Pharmacotherapy in Cardiology</journal-title><trans-title-group xml:lang="ru"><trans-title>Рациональная Фармакотерапия в Кардиологии</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1819-6446</issn><issn pub-type="epub">2225-3653</issn><publisher><publisher-name>«SILICEA-POLIGRAF» LLC</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.20996/1819-6446-2022-08-08</article-id><article-id custom-type="elpub" pub-id-type="custom">rpcardio-2798</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ASSOCIATED PROBLEMS OF CARDIOLOGY</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>СМЕЖНЫЕ ВОПРОСЫ КАРДИОЛОГИИ</subject></subj-group></article-categories><title-group><article-title>Acute Heart Failure in a Pregnant Woman with Preeclampsia: a Rare Case of Takotsubo Syndrome</article-title><trans-title-group xml:lang="ru"><trans-title>Острая сердечная недостаточность у беременной женщины с преэклампсией: редкий случай синдрома такоцубо</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-1898-084X</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Болдуева</surname><given-names>С. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Boldueva</surname><given-names>S. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Болдуева Светлана Афанасьевна.</p><p>Санкт-Петербург.</p></bio><bio xml:lang="en"><p>Svetlana A. Boldueva.</p><p>St. Petersburg.</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-3107-1691</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Евдокимов</surname><given-names>Д. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Evdokimov</surname><given-names>D. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Евдокимов Дмитрий Сергеевич.</p><p>Санкт-Петербург.</p></bio><bio xml:lang="en"><p>Dmitry S. Evdokimov.</p><p>St. Petersburg.</p></bio><email xlink:type="simple">kasabian244@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-6298-547X</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Рождественская</surname><given-names>М. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Rozhdestvenskaya</surname><given-names>M. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Рождественская Марина Витальевна.</p><p>Санкт-Петербург.</p></bio><bio xml:lang="en"><p>Marina V. Rozhdestvenskaya.</p><p>St. Petersburg.</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-5634-8303</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Рукояткина</surname><given-names>Е. A.</given-names></name><name name-style="western" xml:lang="en"><surname>Rukoyatkina</surname><given-names>E. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Рукояткина Елена Алексевна.</p><p>Санкт-Петербург.</p></bio><bio xml:lang="en"><p>Elena A. Rukoyatkina.</p><p>St. Petersburg.</p></bio><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Северо-Западный государственный медицинский университет им. И.И. Мечникова</institution><country>Россия</country></aff><aff xml:lang="en"><institution>I.I. Mechnikov North-Western State Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>СПб ГБУЗ «Родильный дом №16»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>SPb GBUZ "Maternity hospital №16"</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2022</year></pub-date><pub-date pub-type="epub"><day>08</day><month>09</month><year>2022</year></pub-date><volume>18</volume><issue>4</issue><fpage>462</fpage><lpage>466</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Boldueva S.A., Evdokimov D.S., Rozhdestvenskaya M.V., Rukoyatkina E.A., 2022</copyright-statement><copyright-year>2022</copyright-year><copyright-holder xml:lang="ru">Болдуева С.А., Евдокимов Д.С., Рождественская М.В., Рукояткина Е.A.</copyright-holder><copyright-holder xml:lang="en">Boldueva S.A., Evdokimov D.S., Rozhdestvenskaya M.V., Rukoyatkina E.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.rpcardio.online/jour/article/view/2798">https://www.rpcardio.online/jour/article/view/2798</self-uri><abstract><p>The mechanisms of takotsubo syndrome, better known as stress-induced cardiomyopathy, are not fully understood. The article presents a clinical case of the development of acute left ventricular failure in a 39-year-old pregnancy against the background of severe preeclampsia. Echocardiography revealed a decrease in global myocardial contractility, hypo-akinesia of the apex and all median parts of the left ventricle, hyperkinesis of the basal parts. After 2 weeks, myocardial contractility was normal, no contractility impairment was found. Two months after the acute episode of the disease, magnetic resonance imaging of the heart was performed, according to which no pathological changes were detected. Based on the clinical picture, electrocardiogram changes, laboratory data and typical transient echocardiographic changes, it was suggested that the patient had takotsubo syndrome.</p></abstract><trans-abstract xml:lang="ru"><p>Механизмы синдрома такоцубо, более известного как стресс-индуцированная кардиомиопатия, до конца не изучены. В статье представлен клинический случай развития острой левожелудочковой сердечной недостаточности у 39-летней женщины на 30 нед беременности на фоне преэклампсии тяжелой степени. При эхокардиографии найдено снижение глобальной сократимости миокарда, гипо-акинезия верхушки и всех срединных отделов левого желудочка, гиперкинез базальных отделов. Через 2 нед сократительная способность миокарда оказалась нормальной, зон нарушения сократимости не выявлено. Спустя 2 мес после острого эпизода заболевания была выполнена магнитно-резонансная томографии сердца, по данным которой патологических изменений выявлено не было. На основании клинической картины, изменений на электрокардиограмме, лабораторных данных и типичных транзиторных изменений эхокардиографии было высказано предположение, что у пациентки имел место синдром такоцубо.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>беременность</kwd><kwd>острая сердечная недостаточность</kwd><kwd>синдром такоцубо</kwd><kwd>преэклампсия</kwd></kwd-group><kwd-group xml:lang="en"><kwd>pregnancy</kwd><kwd>acute heart failure</kwd><kwd>takotsubo syndrome</kwd><kwd>preeclampsia</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Мареев В.Ю., Фомин И.В., Агеев Ф.Т., и др. Клинические рекомендации ОССН-РКО-РНМОТ. Сердечная недостаточность: хроническая (ХСН) и острая декомпенсированная (ОДСН). Диагностика, профилактика и лечение. Кардиология. 2018;58(6S):8-158. 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