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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">rpcardio</journal-id><journal-title-group><journal-title xml:lang="en">Rational Pharmacotherapy in Cardiology</journal-title><trans-title-group xml:lang="ru"><trans-title>Рациональная Фармакотерапия в Кардиологии</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1819-6446</issn><issn pub-type="epub">2225-3653</issn><publisher><publisher-name>«SILICEA-POLIGRAF» LLC</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.20996/1819-6446-2022-09-04</article-id><article-id custom-type="elpub" pub-id-type="custom">rpcardio-2818</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL STUDIES</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ ИССЛЕДОВАНИЯ</subject></subj-group></article-categories><title-group><article-title>Pararenalfat Tissue: Rate of Pararenal Obesity and Relation with Anthropometric Indices of Obesity</article-title><trans-title-group xml:lang="ru"><trans-title>Паранефральная жировая ткань: частота паранефрального ожирения и связь с антропометрическими индексами ожирения</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-0758-5609</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Подзолков</surname><given-names>В. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Podzolkov</surname><given-names>V. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Подзолков Валерий Иванович</p><p>eLibrary SPIN 8683-2155</p><p> Москва </p></bio><bio xml:lang="en"><p>Valery I. Podzolkov </p><p> Moscow </p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-2699-1610</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Брагина</surname><given-names>А. Е.</given-names></name><name name-style="western" xml:lang="en"><surname>Bragina</surname><given-names>A. E.</given-names></name></name-alternatives><bio xml:lang="ru"><p> Брагина Анна Евгеньевна</p><p>eLibrary SPIN 3753-5539</p><p> Москва </p></bio><bio xml:lang="en"><p> Anna E. Bragina </p><p> Moscow </p></bio><email xlink:type="simple">anna.bragina@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-8202-4492</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Осадчий</surname><given-names>К. К.</given-names></name><name name-style="western" xml:lang="en"><surname>Osadchiy</surname><given-names>K. K.</given-names></name></name-alternatives><bio xml:lang="ru"><p> Осадчий Константин Константинович</p><p> Москва </p></bio><bio xml:lang="en"><p> Konstantin K. Osadchiy </p><p> Moscow </p><p> </p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-3461-6703</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Родионова</surname><given-names>Ю. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Rodionova</surname><given-names>J. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p> Родионова Юлия Нурисламовна </p><p> Москва </p></bio><bio xml:lang="en"><p> Julia N. Rodionova </p><p> Moscow </p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-6670-7178</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Баютина</surname><given-names>Д. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Bayutina</surname><given-names>D. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p> Баютина Дарья Александровна</p><p> Москва </p></bio><bio xml:lang="en"><p>Darya А. Bayutina </p><p> Moscow </p><p> </p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Первый Московский государственный медицинский университет им. И.М. Сеченова (Сеченовский Университет)</institution><country>Россия</country></aff><aff xml:lang="en"><institution>I.M. Sechenov First Moscow State Medical University (Sechenov University)</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2022</year></pub-date><pub-date pub-type="epub"><day>02</day><month>11</month><year>2022</year></pub-date><volume>18</volume><issue>5</issue><fpage>516</fpage><lpage>521</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Podzolkov V.I., Bragina A.E., Osadchiy K.K., Rodionova J.N., Bayutina D.A., 2022</copyright-statement><copyright-year>2022</copyright-year><copyright-holder xml:lang="ru">Подзолков В.И., Брагина А.Е., Осадчий К.К., Родионова Ю.Н., Баютина Д.А.</copyright-holder><copyright-holder xml:lang="en">Podzolkov V.I., Bragina A.E., Osadchiy K.K., Rodionova J.N., Bayutina D.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.rpcardio.online/jour/article/view/2818">https://www.rpcardio.online/jour/article/view/2818</self-uri><abstract><p>Aim. To study a rate of excessive pararenal fat tissue (PRFT) thickness and its relationship with anthropometric obesity indices.Material and methods. 372 patients (152 men and 220 women) were included in the study, the average age was 63.5±13.3 years. There were measured: height, weight, waist circumference (WC), hip circumference (HC), body mass index (BMI), WC/height ratio, sagittal abdominal diameter (SAD), body fat percentage (BFP), body surface area (BSA), body adiposity index (BAI) and visceral obesity index (VAI). All subjects underwent abdominal multispiral computed tomography. PRFT thickness was detected on a single slice at the level of the left renal vein.Results. 27% of the examined group had BMI&lt;25 kg/m2, 28% – excessive body mass, 45% – obesity. The median PRFT thickness was 1.61 (1.03; 2.46) cm. There were correlations between PRFT thickness and glucose (r=0,64, p&lt;0,05) and uric acid (r=0,46, p&lt;0,05) levels. The threshold of referential PRFT thickness was 1,91cm. The rate of pararenal obesity was 9,9% among those with normal body mass, 29,3% in excessive body mass, 66,1% – in 1 class obesity, 67,7% – in 2 class, and 90,1% – in 3 class. The correlation analysis revealed a significant positive correlation between the PRFT thickness and obesity indices with exception of VAI and BAI: with BMI (r=0.43, p&lt;0.05), WC (r=0.57, p&lt;0.05), SAD (r=0.58, p&lt;0.05), BFP (r=0.48, p&lt;0.05), WC/height ratio (r=0.46, p&lt;0.05), and BSA (r=0.58, p&lt;0.05).Conclusion. Excessive PRFT may be detected isolated without any external anthropometric signs of obesity, wherein it is an active component of metabolic disorders typical for obesity. The most significant indices for the detection of pararenal obesity may be WC, SAD, and BSA.</p></abstract><trans-abstract xml:lang="ru"><p>Цель. Изучить частоту избыточной толщины паранефральной жировой ткани (ПНЖТ) и ее взаимосвязь с антропометрическими индексами ожирения.Материал и методы. Обследованы 372 пациента (152 мужчины и 220 женщин), средний возраст 63,5±13,3 лет. Проведены измерения роста, веса, окружности талии (ОТ), окружности бедер (ОБ), расчет индекса массы тела (ИМТ), соотношения ОТ/рост, сагиттального абдоминального диаметра, процента жира в организме, площади поверхности тела, индекса ожирения тела и индекса висцерального ожирения. Всем исследуемым была выполнена мультиспиральная компьютерная томография брюшной полости. Определение толщины ПНЖТ проводилось на одном срезе на уровне левой почечной вены.Результаты. В обследуемой группе ИМТ&lt;25кг/м2 был у 27%, у 28% была выявлена повышенная масса тела, у 45% – ожирение. Медиана толщины ПНЖТ составила 1,61 (1,03; 2,46) см. Выявлены корреляции толщины ПНЖТ с уровнем глюкозы плазмы крови натощак (r=0,64, p&lt;0,05) и мочевой кислоты (r=0,46, p&lt;0,05). Граница нормальной ориентировочной нормы толщины ПНЖТ составила 1,91 см. Частота паранефрального ожирения составила 9,9% среди лиц с нормальной массой тела, 29,3% среди лиц с избыточной массой тела, 66,1% в группе с ожирением 1 степени, 67,7% – 2 степени и 90,1% – 3 степени. При проведении корреляционного анализа была выявлена значимая положительная связь между объемом ПНЖТ со всеми индексами ожирения, кроме индекса висцерального ожирения и индекса ожирения тела: с ИМТ (r=0,43, p&lt;0,05), ОТ (r=0,57, p&lt;0,05), сагиттальным абдоминальным диаметром (r=0,58, p&lt;0,05), процентом жира в организме (r=0,48, p&lt;0,05), ОТ/рост (r=0,46, p&lt;0,05) и площадью поверхности тела (r=0,58, p&lt;0,05).Заключение. Избыточная ПНЖТ может выявляться изолировано без внешних антропометрических признаков ожирения, будучи при этом активным компонентом метаболических нарушений, свойственных ожирению. Наиболее значимыми индексами для выявления паранефрального ожирения могут быть ОТ, сагиттальный абдоминальный диаметр и площадь поверхности тела.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>ожирение</kwd><kwd>эктопическая жировая ткань</kwd><kwd>индексы ожирения</kwd><kwd>паранефральная жировая ткань</kwd></kwd-group><kwd-group xml:lang="en"><kwd>obesity</kwd><kwd>ectopic fat tissue</kwd><kwd>obesity indices</kwd><kwd>pararenal fat tissue</kwd></kwd-group><funding-group><funding-statement xml:lang="ru">Исследование проведено при поддержке Сеченовского Университета.</funding-statement><funding-statement xml:lang="en">The study was performed with the support of the Sechenov University.</funding-statement></funding-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">GBD 2015 Obesity Collaborators, Afshin A, Forouzanfar MH, Reitsma MB, et al. 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