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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">rpcardio</journal-id><journal-title-group><journal-title xml:lang="en">Rational Pharmacotherapy in Cardiology</journal-title><trans-title-group xml:lang="ru"><trans-title>Рациональная Фармакотерапия в Кардиологии</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1819-6446</issn><issn pub-type="epub">2225-3653</issn><publisher><publisher-name>«SILICEA-POLIGRAF» LLC</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.20996/1819-6446-2014-10-2-238-244</article-id><article-id custom-type="elpub" pub-id-type="custom">rpcardio-29</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>CURRENT QUESTIONS OF CLINICAL PHARMACOLOGY</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>АКТУАЛЬНЫЕ  ВОПРОСЫ  КЛИНИЧЕСКОЙ ФАРМАКОЛОГИИ</subject></subj-group></article-categories><title-group><article-title>ADVANTAGES OF COMBINATION THERAPY OF HYPERTENSION WITH CALCIUM CHANNEL BLOCKER AND ANGIOTENSIN-CONVERTING ENZYME INHIBITOR IN PATIENTS WITH IMPAIRED RENAL FUNCTION</article-title><trans-title-group xml:lang="ru"><trans-title>ПРЕИМУЩЕСТВА КОМБИНИРОВАННОЙ ТЕРАПИИ АРТЕРИАЛЬНОЙ ГИПЕРТОНИИ АНТАГОНИСТОМ КАЛЬЦИЯ И ИНГИБИТОРОМ АНГИОТЕНЗИНПРЕВРАЩАЮЩЕГО ФЕРМЕНТА У ПАЦИЕНТОВ С НАРУШЕНИЯМИ ФУНКЦИИ ПОЧЕК</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Джаиани</surname><given-names>Н. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Dzhaiani</surname><given-names>N. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Джаиани Нино Амирановна – доктор медицинских наук, профессор кафедры скорой  медицинской помощи факультета последипломного образования</p></bio><email xlink:type="simple">doctorni@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Московский государственный медико-стоматологический университет им. А.И. Евдокимова</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Moscow State University of Medicine and Dentistry named after A.I. Evdokimov</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2014</year></pub-date><pub-date pub-type="epub"><day>19</day><month>09</month><year>2015</year></pub-date><volume>10</volume><issue>2</issue><fpage>238</fpage><lpage>244</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Dzhaiani N.A., 2015</copyright-statement><copyright-year>2015</copyright-year><copyright-holder xml:lang="ru">Джаиани Н.А.</copyright-holder><copyright-holder xml:lang="en">Dzhaiani N.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.rpcardio.online/jour/article/view/29">https://www.rpcardio.online/jour/article/view/29</self-uri><abstract><p>Up-to-date data on combination therapy of arterial hypertension in patients with chronic kidney disease are presented. Special attention is paid to the fixed combination of calcium antagonist lercanidipine and angiotensin-converting enzyme inhibitor enalapril.</p></abstract><trans-abstract xml:lang="ru"><p>Представлены современные данные по комбинированной  терапии артериальной гипертонии у пациентов с хронической болезнью почек. Особое внимание уделено фиксированной комбинации антагониста кальция лерканидипина и ингибитора ангиотензинпревращающего фермента эналаприла.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>хроническая болезнь почек</kwd><kwd>комбинированная антигипертензивная терапия</kwd><kwd>антагонист кальция</kwd><kwd>ингибитор ангиотензинпревращающего фермента</kwd></kwd-group><kwd-group xml:lang="en"><kwd>chronic kidney disease</kwd><kwd>combination antihypertensive therapy</kwd><kwd>calcium antagonist</kwd><kwd>angiotensin-converting enzyme inhibitor</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Cardiovascular risk and chronic kidney disease: cardio nephroprotection strategy. National guidelines. Available at: http://scardio.ru/content/Guidelines/nefrorek2013.doc.Accessed by: 20.04.2013. 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