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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">rpcardio</journal-id><journal-title-group><journal-title xml:lang="en">Rational Pharmacotherapy in Cardiology</journal-title><trans-title-group xml:lang="ru"><trans-title>Рациональная Фармакотерапия в Кардиологии</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1819-6446</issn><issn pub-type="epub">2225-3653</issn><publisher><publisher-name>«SILICEA-POLIGRAF» LLC</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.20996/1819-6446-2014-10-6-679-687</article-id><article-id custom-type="elpub" pub-id-type="custom">rpcardio-309</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>THERAPY GUIDELINES</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>РЕКОМЕНДАЦИИ ПО ЛЕЧЕНИЮ</subject></subj-group></article-categories><title-group><article-title>THE SIGNIFICANCE OF PLATELET FUNCTIONAL ACTIVITY TESTING IN THE PREVENTION OF CARDIOVASCULAR COMPLICATIONS IN PATIENTS RECEIVING ANTIPLATELET THERAPY</article-title><trans-title-group xml:lang="ru"><trans-title>РОЛЬ ТЕСТИРОВАНИЯ ФУНКЦИОНАЛЬНОЙ АКТИВНОСТИ ТРОМБОЦИТОВ В ПРОФИЛАКТИКЕ СЕРДЕЧНО-СОСУДИСТЫХ ОСЛОЖНЕНИЙ У БОЛЬНЫХ, ПОЛУЧАЮЩИХ АНТИТРОМБОЦИТАРНУЮ ТЕРАПИЮ</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Андреев</surname><given-names>Д. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Andreev</surname><given-names>D. A.</given-names></name></name-alternatives><email xlink:type="simple">dennan@mail.ru</email></contrib></contrib-group><pub-date pub-type="collection"><year>2014</year></pub-date><pub-date pub-type="epub"><day>26</day><month>09</month><year>2015</year></pub-date><volume>10</volume><issue>6</issue><fpage>679</fpage><lpage>687</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Andreev D.A., 2015</copyright-statement><copyright-year>2015</copyright-year><copyright-holder xml:lang="ru">Андреев Д.А.</copyright-holder><copyright-holder xml:lang="en">Andreev D.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.rpcardio.online/jour/article/view/309">https://www.rpcardio.online/jour/article/view/309</self-uri><abstract><p>Conclusion of Interdisciplinary Expert Council of Russian Association of Angiologists and Vascular Surgeons, Russian Scientific Society of Endovascular Surgeons and Interventional Radiologists, National Stroke Association, National Scientific Inflammation Society The Conclusion of Interdisciplinary Expert Council on the significance of testing of platelet functional activity in the prevention of cardiovascular complications in patients receiving antiplatelet therapy is presented. Indications for antiplatelet therapy, relation of platelet reactivity with the risk of adverse events, as well as factors that contribute to high residual platelet reactivity in patients receiving antiplatelet therapy are considered. The results of studies on the correction of antiplatelet therapy based on aggregometry data, indications for its implementation in clinical practice, as well as methods for evaluation of residual platelet reactivity are discussed separately.</p></abstract><trans-abstract xml:lang="ru"><p>Заключение междисциплинарного Совета Экспертов Российского общества ангиологов и сосудистых хирургов, Российского научного общества специалистов по рентгенэндоваскулярной диагностике и лечению, Национальной ассоциации по борьбе с инсультами, Национального научного общества воспаления Представлено заключение междисциплинарного Совета Экспертов о роли тестирования функциональной активности тромбоцитов в профилактике сердечно-сосудистых осложнений у больных, получающих антитромбоцитарную терапию. Рассмотрены показания к антитромбоцитарной терапии, связь реактивности тромбоцитов на фоне приема антитромбоцитарной терапии с риском развития неблагоприятных событий, а также факторы, обуславливающие высокую остаточную реактивность тромбоцитов на фоне приема антитромбоцитарных препаратов. Отдельно рассматриваются результаты исследований по коррекции антитромбоцитарной терапии на основании данных агрегатометрии, показания к ее проведению в клинической практике, а также методы оценки остаточной реактивности тромбоцитов.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>функциональная активность тромбоцитов</kwd><kwd>антитромбоцитарная терапия</kwd><kwd>высокая остаточная реактивность тромбоцитов</kwd><kwd>агрегатометрия</kwd></kwd-group><kwd-group xml:lang="en"><kwd>functional platelet activity</kwd><kwd>antiplatelet therapy</kwd><kwd>high residual platelet reactivity</kwd><kwd>aggregometry</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Belenkov YN, Oganov RG. Cardiology: national guidance. Moscow: GEOTAR-Media; 2010. Russian (Беленков Ю.Н., Оганов Р.Г. Кардиология: национальное руководство. 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