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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">rpcardio</journal-id><journal-title-group><journal-title xml:lang="en">Rational Pharmacotherapy in Cardiology</journal-title><trans-title-group xml:lang="ru"><trans-title>Рациональная Фармакотерапия в Кардиологии</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1819-6446</issn><issn pub-type="epub">2225-3653</issn><publisher><publisher-name>«SILICEA-POLIGRAF» LLC</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.20996/1819-6446-2015-11-5-450-458</article-id><article-id custom-type="elpub" pub-id-type="custom">rpcardio-316</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL STUDIES</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ ИССЛЕДОВАНИЯ</subject></subj-group></article-categories><title-group><article-title>Excess winter cardiovascular morbidity in Ivanovo Region in 2009-2013 years</article-title><trans-title-group xml:lang="ru"><trans-title>ИЗБЫТОЧНАЯ ЗАБОЛЕВАЕМОСТЬ СЕРДЕЧНО-СОСУДИСТЫМИ ЗАБОЛЕВАНИЯМИ В ЗИМНИЙ ПЕРИОД В ИВАНОВСКОЙ ОБЛАСТИ В 2009-2013 ГГ</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Концевая</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Kontsevaya</surname><given-names>A. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>д.м.н., руководитель лаборатории экономического анализа эпидемиологических исследований и профилактических технологий отдела эпидемиологии хронических неинфекционных заболеваний, Государственный научно-исследовательский центр профилактической медицины (ГНИЦ ПМ) </p></bio><bio xml:lang="en"><p>MD, PhD, Head of Laboratory of Economic Analysis of Epidemiologic Studies and Preventive Programs, Department of Epidemiology of Chronic Non-infectious Diseases, State Research Centre for Preventive Medicine (SRC PM)</p></bio><email xlink:type="simple">akontsevaya@gnicpm.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Баланова</surname><given-names>Ю. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Balanova</surname><given-names>J. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>к.м.н., в.н.с. той же лаборатории</p></bio><bio xml:lang="en"><p>MD, PhD, Leading Researcher of the same laboratory</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Лукьянов</surname><given-names>М. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Loukianov</surname><given-names>M. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>к.м.н., в.н.с. отдела клинической кардиологии и молекулярной генетики ГНИЦ ПМ</p></bio><bio xml:lang="en"><p>MD, PhD, Leading Researcher of the Department of Clinical Cardiology and Molecular Genetics, SRC PM </p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Худяков</surname><given-names>М. Б.</given-names></name><name name-style="western" xml:lang="en"><surname>Khudyakov</surname><given-names>M. B.</given-names></name></name-alternatives><bio xml:lang="ru"><p>ведущий инженер лаборатории экономического анализа эпидемиологических исследований и профилактических технологий отдела эпидемиологии хронических неинфекционных заболеваний ГНИЦ ПМ</p></bio><bio xml:lang="en"><p>Leading Engineer of the Laboratory of Economic Analysis of Epidemiologic Studies and Preventive Programs, Department of Epidemiology of Chronic Non-infectious Diseases, SRC PM</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Белова</surname><given-names>О. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Belova</surname><given-names>O. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>зам. главного врача Кардиологического диспансера г. Иваново</p></bio><bio xml:lang="en"><p>MD, Deputy Chief Doctor of the Ivanovo Municipal Cardiology Hospital</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Романчук</surname><given-names>С. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Romanchuk</surname><given-names>S. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>к.м.н, главный врач Кардиологического диспансера г. Иваново</p></bio><bio xml:lang="en"><p>MD, PhD, Chief Doctor of the Ivanovo Municipal Cardiology Hospital </p></bio><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Государственный научно-исследовательский центр профилактической медицины. 101990, Москва, Петроверигский пер., 10</institution><country>Россия</country></aff><aff xml:lang="en"><institution>State Research Centre for Preventive Medicine. Petroverigsky per. 10, Moscow, 101990, Russia</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Кардиологический диспансер г. Иваново. 153012, Иваново, Шереметевский пр., 22</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Ivanovo Municipal Cardiology Hospital. Sheremetyevsky prosp. 22, Ivanovo, 153012 Russia</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2015</year></pub-date><pub-date pub-type="epub"><day>03</day><month>11</month><year>2015</year></pub-date><volume>11</volume><issue>5</issue><fpage>450</fpage><lpage>458</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Kontsevaya A.V., Balanova J.A., Loukianov M.M., Khudyakov M.B., Belova O.A., Romanchuk S.V., 2015</copyright-statement><copyright-year>2015</copyright-year><copyright-holder xml:lang="ru">Концевая А.В., Баланова Ю.А., Лукьянов М.М., Худяков М.Б., Белова О.А., Романчук С.В.</copyright-holder><copyright-holder xml:lang="en">Kontsevaya A.V., Balanova J.A., Loukianov M.M., Khudyakov M.B., Belova O.A., Romanchuk S.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.rpcardio.online/jour/article/view/316">https://www.rpcardio.online/jour/article/view/316</self-uri><abstract><p>Chronic non-infectious diseases are characterized by irregular morbidity and mortality throughout a year. Aim. To study excess cardiovascular morbidity during winter in Ivanovo Region in 2009-2013 years. Material and methods. Excess winter morbidity index (EWMI) was calculated using special formula. The incidence of cardiovascular diseases (CVDs) was determined according to the data from the medical information-analytic center of Ivanovo Region. The index was calculated for CVDs in general, for arterial hypertension (HT) and for acute forms of CVDs (acute myocardial infarction and stroke). Results. The mean EWMI for CVDs for 5 years of the follow-up made up to 77.2% and was higher in women than in men (80% vs 69.5%, respectively). People of working age had lower excess winter morbidity than the population older than working age (53.1% and 88%, respectively). EWMI for CVDs had significant variability and ranged from 29.0% (2013 year) to 81.1% (2010 year) in men and from 25.2% to 82.9% in women in the same years. In general, the 5-year mean EWMI for HT was 72.7%; it was higher in men than in women in most of the analyzed years of follow-up. We had revealed the heterogeneity of the EWMI for HT during the analyzed period in each analyzed group (the minimal values were found in 2011 after the heat wave in 2010). EWMI for myocardial infarction demonstrated excess winter morbidity, men and women had in general similar indices (31.0% and 28.4%, respectively), but it was higher in people of working age as compared with the older ones. This index had a wide range of values. In case of stroke we had revealed no excess winter morbidity; this index was equal throughout a year. Conclusion. The influence on excess winter morbidity can result in the reduction of cardiovascular morbidity and mortality due to the decreased effect of risk factors; it would also optimize a load on healthcare system, the season irregularity of which must be taken into account when planning a work of medical centers. </p></abstract><trans-abstract xml:lang="ru"><p>Хронические неинфекционные заболевания характеризуются неравномерной заболеваемостью и смертностью в течение года. Цель. Изучить избыточную заболеваемость от сердечно-сосудистых заболеваний (ССЗ) в зимний период в Ивановской области в 2009-2013 гг. Материал и методы. Проведен расчет индекса избыточной заболеваемости в зимний период (ИИЗЗП) по специальной формуле. Количество ССЗ определяли по данным медицинского информационно-аналитического центра Ивановской области. Индекс рассчитывали для ССЗ в целом, для артериальной гипертензии (АГ) и для острых форм ССЗ (инфаркт миокарда и инсульт). Результаты. Средний ИИЗЗП для ССЗ за 5 лет составил 77,2%, и оказался у женщин несколько выше, чем у мужчин (80,0% против 69,5%, соответственно). Среди лиц трудоспособного возраста избыточная заболеваемость в зимний период оказалась ниже, чем среди населения старше трудоспособного возраста (53,1 и 88%, соответственно). ИИЗЗП для ССЗ характеризовался значительной вариабельностью и колебался от 29,0% (2013 г.) до 81,1% (2010 г.) у мужчин и от 25,2% до 82,9% у женщин в те же годы. Средний за 5 лет ИИЗЗП для АГ в целом составил 72,7%, выше – у мужчин в сравнении с женщинами в большинстве анализируемых лет наблюдения. Выявлена неоднородность показателя ИИЗЗП для АГ в течение анализируемого периода в каждой анализируемой группе (минимальные значения отмечены в 2011 г., вслед за волной жары 2010 г. При анализе ИИЗЗП для инфаркта миокарда выявлена избыточная заболеваемость в зимний период, показатели у мужчин и женщин в целом – близки (31,0% и 28,4%, соответственно), но выше – у лиц трудоспособного возраста по сравнению с лицами более старших возрастных групп. Этот показатель имел широкий разброс значений. Избыточной заболеваемости инсультом в зимний период не выявлено – этот показатель был равномерен в течение года. Заключение. Воздействие на избыточную заболеваемость в зимний период – это резерв снижения заболеваемости и смертности от ССЗ за счет снижения воздействия рисков, и важный фактор оптимизации нагрузки на систему здравоохранения, сезонную неравномерность которой необходимо учитывать при планировании работы медицинских учреждений. </p></trans-abstract><kwd-group xml:lang="ru"><kwd>избыточная заболеваемость в зимний период</kwd><kwd>хронические неинфекционные заболевания</kwd><kwd>сердечно-сосудистые заболевания</kwd></kwd-group><kwd-group xml:lang="en"><kwd>excess winter morbidity</kwd><kwd>chronic non-infectious diseases</kwd><kwd>cardiovascular diseases</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Fares A. Winter Cardiovascular Diseases Phenomenon. N. Am J Med Sci 2013; 5(4): 266-79.</mixed-citation><mixed-citation xml:lang="en">Fares A. Winter Cardiovascular Diseases Phenomenon. N. Am J Med Sci 2013; 5(4): 266-79.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Mercer JB Cold – an underrated risk factor for health. Environmental Research 2003; 92:8-13.</mixed-citation><mixed-citation xml:lang="en">Mercer JB Cold – an underrated risk factor for health. Environmental Research 2003; 92:8-13.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Healy JD. Excess winter mortality in Europe: a cross country analysis identifying key risk factors. J Epidemiol Commun Health 2003; 57:784-9.</mixed-citation><mixed-citation xml:lang="en">Healy JD. Excess winter mortality in Europe: a cross country analysis identifying key risk factors. J Epidemiol Commun Health 2003; 57:784-9.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Analitis A., Katsouyanni K, Biggeri A. et al. Effects of Cold Weather on Mortality: Results From 15 European Cities Within the PHEWE Project. American Journal of Epidemiology 2008; 168(12): 1397-408.</mixed-citation><mixed-citation xml:lang="en">Analitis A., Katsouyanni K, Biggeri A. et al. Effects of Cold Weather on Mortality: Results From 15 European Cities Within the PHEWE Project. American Journal of Epidemiology 2008; 168(12): 1397-408.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Fowler T, Southgate RJ, Waite T et al. Excess Winter Deaths in Europe: A multi-country descriptive analysis. Eur J Public Health 2015;25(2):339-45.</mixed-citation><mixed-citation xml:lang="en">Fowler T, Southgate RJ, Waite T et al. Excess Winter Deaths in Europe: A multi-country descriptive analysis. Eur J Public Health 2015;25(2):339-45.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Kontsevaya A.V., Lukyanov M.M., Khudyakov M.B. Seasonal and monthly changes of mortality in Russian Federation regions with different climate and geographic variables. Rossiyskiy Kardiologicheskiy Zhurnal 2014;11:25-30. In Russian (Концевая А. В., Лукьянов М. М., Худяков М. Б., Сезонные и помесячные изменения смертности в регионах Российский Федерации с различными климато-географическими характеристиками. Российский Кардиологический Журнал 2014;11:25-30).</mixed-citation><mixed-citation xml:lang="en">Kontsevaya A.V., Lukyanov M.M., Khudyakov M.B. Seasonal and monthly changes of mortality in Russian Federation regions with different climate and geographic variables. Rossiyskiy Kardiologicheskiy Zhurnal 2014;11:25-30. In Russian (Концевая А. В., Лукьянов М. М., Худяков М. Б., Сезонные и помесячные изменения смертности в регионах Российский Федерации с различными климато-географическими характеристиками. Российский Кардиологический Журнал 2014;11:25-30).</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Kontsevaia A.V., Lukyanov M.M., Balanova Iu.A. et al. Social and economic burden caused by excess winter cardiovascular deaths in the Russian Federation''s regions with different climatic and geographic characteristics. Profilakticheskaya Meditsina 2014, 6:21-25. In Russian (Концевая А.В., Лукьянов М.М., Баланова Ю.А. и др. Социально-экономический ущерб, вызванный избыточной смертностью от сердечно-сосудистых заболеваний в зимний период в регионах Российской Федерации с различными климато-географическими характеристиками. Профилактическая Медицина 2014; 6: 21-5).</mixed-citation><mixed-citation xml:lang="en">Kontsevaia A.V., Lukyanov M.M., Balanova Iu.A. et al. Social and economic burden caused by excess winter cardiovascular deaths in the Russian Federation''s regions with different climatic and geographic characteristics. Profilakticheskaya Meditsina 2014, 6:21-25. In Russian (Концевая А.В., Лукьянов М.М., Баланова Ю.А. и др. Социально-экономический ущерб, вызванный избыточной смертностью от сердечно-сосудистых заболеваний в зимний период в регионах Российской Федерации с различными климато-географическими характеристиками. Профилактическая Медицина 2014; 6: 21-5).</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Maksimova T.M., Belov V.B., Saurina O.S., Lushkina N. P. The seasonality of population contacts with medical organizations because of diseases of blood circulation system. Problemy Sotsialnoi Gigieny, Zdravookhraneniya, i Istorii Meditsiny 2014;4:3-6. In Russian (Максимова Т.М., Белов В.Б., Саурина О.С., Лушкина Н.П. Сезонность контактов населения с медицинскими организациями в связи с заболеваниями системы кровообращения. Проблемы Социальной Гигиены, Здравоохранения и Истории Медицины 2014;4:3-6).</mixed-citation><mixed-citation xml:lang="en">Maksimova T.M., Belov V.B., Saurina O.S., Lushkina N. P. The seasonality of population contacts with medical organizations because of diseases of blood circulation system. Problemy Sotsialnoi Gigieny, Zdravookhraneniya, i Istorii Meditsiny 2014;4:3-6. In Russian (Максимова Т.М., Белов В.Б., Саурина О.С., Лушкина Н.П. Сезонность контактов населения с медицинскими организациями в связи с заболеваниями системы кровообращения. Проблемы Социальной Гигиены, Здравоохранения и Истории Медицины 2014;4:3-6).</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Fullerton K. J., Crawford V. L. S. The Winter Bed Crisis – Quantifying seasonal effects on bed usage, Quarterly Journal of Medicine 1999; 92: 199-206.</mixed-citation><mixed-citation xml:lang="en">Fullerton K. J., Crawford V. L. S. The Winter Bed Crisis – Quantifying seasonal effects on bed usage, Quarterly Journal of Medicine 1999; 92: 199-206.</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Chereshnev V. A., Gamburtsev A.G., Sigachev A. V. Dynamics of Ambulance Calls in Moscow (20062011) «Space and Time» Journal 2013;12:220-8. In Russian (Черешнев В.А., Гамбурцев А.Г., Сигачев А.В. Динамика вызовов скорой помощи Москвы (2006-2011 г.г). Пространство и Время 2013;12:220-8).</mixed-citation><mixed-citation xml:lang="en">Chereshnev V. A., Gamburtsev A.G., Sigachev A. V. Dynamics of Ambulance Calls in Moscow (20062011) «Space and Time» Journal 2013;12:220-8. In Russian (Черешнев В.А., Гамбурцев А.Г., Сигачев А.В. Динамика вызовов скорой помощи Москвы (2006-2011 г.г). Пространство и Время 2013;12:220-8).</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Barbarash OL, Fomina NV, Martsiyash AA. Association of the season of birth and trimesters of current year of the coronary heart disease patients with the risk of myocardial infarction and its complications. Therapeutic Archive 2002, 9: 30-33. In Russian (Барбараш О.Л., Фомина Н.В., Марцияш А.А. Связь сезона года рождения и триместров индивидуального года больных ишемической болезнью сердца с риском развития инфаркта миокарда и его осложнений. Терапевтический Архив 2002;74 (9):30-3).</mixed-citation><mixed-citation xml:lang="en">Barbarash OL, Fomina NV, Martsiyash AA. Association of the season of birth and trimesters of current year of the coronary heart disease patients with the risk of myocardial infarction and its complications. Therapeutic Archive 2002, 9: 30-33. In Russian (Барбараш О.Л., Фомина Н.В., Марцияш А.А. Связь сезона года рождения и триместров индивидуального года больных ишемической болезнью сердца с риском развития инфаркта миокарда и его осложнений. Терапевтический Архив 2002;74 (9):30-3).</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Fowler T., Southgate R.J, Waite T. et al. Excess Winter Deaths in Europe: a multi-country descriptive analysis. Eur J Public Health 2015;25:2 339-345</mixed-citation><mixed-citation xml:lang="en">Fowler T., Southgate R.J, Waite T. et al. Excess Winter Deaths in Europe: a multi-country descriptive analysis. Eur J Public Health 2015;25:2 339-345</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Katsouyanni K., Biggeri A. Et al. Effects of Cold Weather on Mortality: Results From 15 European Cities Within the PHEWE Project. Am J Epidemiol 2008, 168 (12):1397-408.</mixed-citation><mixed-citation xml:lang="en">Katsouyanni K., Biggeri A. Et al. Effects of Cold Weather on Mortality: Results From 15 European Cities Within the PHEWE Project. Am J Epidemiol 2008, 168 (12):1397-408.</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Khan R.H., Halder D. Effect of seasonal variation on hospital admission due to cardiovascular disease findings from an observational study in a divisional hospital in Bangladesh. BMC Cardiovasc Disord 2014;14:76.</mixed-citation><mixed-citation xml:lang="en">Khan R.H., Halder D. Effect of seasonal variation on hospital admission due to cardiovascular disease findings from an observational study in a divisional hospital in Bangladesh. BMC Cardiovasc Disord 2014;14:76.</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">Ribera-Casado J. M. Ageing and the cardiovascular system. Z Geront Geriat 1999; 32(6): 412-9.</mixed-citation><mixed-citation xml:lang="en">Ribera-Casado J. M. Ageing and the cardiovascular system. Z Geront Geriat 1999; 32(6): 412-9.</mixed-citation></citation-alternatives></ref><ref id="cit16"><label>16</label><citation-alternatives><mixed-citation xml:lang="ru">Van den Akker M., Buntinx F., Roos S., Knottnerus J. A. Problems in determining occurrence rates of multimorbidity. J Clin Epidem 2001, 54(7):675-9.</mixed-citation><mixed-citation xml:lang="en">Van den Akker M., Buntinx F., Roos S., Knottnerus J. A. Problems in determining occurrence rates of multimorbidity. J Clin Epidem 2001, 54(7):675-9.</mixed-citation></citation-alternatives></ref><ref id="cit17"><label>17</label><citation-alternatives><mixed-citation xml:lang="ru">Boytsov S. A., Balanova Y. A., Shalnova S. A. Arterial hypertension among individuals of 25-64 years old: prevalence, awareness, treatment and control. By the data from ECCD. Kardiovaskulyarnaya Terapiya i Profilaktika 2014; 14 (4): 4-14. In Russian (Бойцов С. А., Баланова Ю. А., Шальнова С. А. Артериальная гипертония среди лиц 25-64 лет: распространенность, осведомленность, лечение и контроль. По материалам исследования ЭССЕ. Кардиоваскулярная Терапия и Профилактика 2014; 14 (4): 4-14).</mixed-citation><mixed-citation xml:lang="en">Boytsov S. A., Balanova Y. A., Shalnova S. A. Arterial hypertension among individuals of 25-64 years old: prevalence, awareness, treatment and control. By the data from ECCD. Kardiovaskulyarnaya Terapiya i Profilaktika 2014; 14 (4): 4-14. In Russian (Бойцов С. А., Баланова Ю. А., Шальнова С. А. Артериальная гипертония среди лиц 25-64 лет: распространенность, осведомленность, лечение и контроль. По материалам исследования ЭССЕ. Кардиоваскулярная Терапия и Профилактика 2014; 14 (4): 4-14).</mixed-citation></citation-alternatives></ref><ref id="cit18"><label>18</label><citation-alternatives><mixed-citation xml:lang="ru">Sinha P, Taneja DK, Singh NP, Saha R. Seasonal variation in prevalence of hypertension: Implications for interpretation. Indian J Public Health 2010;54:7-10.</mixed-citation><mixed-citation xml:lang="en">Sinha P, Taneja DK, Singh NP, Saha R. Seasonal variation in prevalence of hypertension: Implications for interpretation. Indian J Public Health 2010;54:7-10.</mixed-citation></citation-alternatives></ref><ref id="cit19"><label>19</label><citation-alternatives><mixed-citation xml:lang="ru">Al-Tamer YY, Al-Hayali JM, Al-Ramadhan EA. Seasonality of hypertension. J Clin Hypertens (Greenwich) 2008;10:125-9.</mixed-citation><mixed-citation xml:lang="en">Al-Tamer YY, Al-Hayali JM, Al-Ramadhan EA. Seasonality of hypertension. J Clin Hypertens (Greenwich) 2008;10:125-9.</mixed-citation></citation-alternatives></ref><ref id="cit20"><label>20</label><citation-alternatives><mixed-citation xml:lang="ru">Smirnova MI, Gorbunov VM, Boytsov SA et al. Seasonal changes in hemodynamic parameters in patients with controlled hypertension and high normal blood pressure in two Russian regions with different climatic characteristics. Part 1: Design and preliminary results. Profilakticheskaya Meditcina 2013; 6: 71-8. In Russian (Смирнова М.И., Горбунов В.М., Бойцов С.А. и др. Сезонные изменения гемодинамических параметров у больных с контролируемой артериальной гипертонией и высоким нормальным артериальным давлением в двух регионах Российской Федерации с различными климатическими характеристиками. Часть 1. Дизайн и предварительные результаты. Профилактическая Медицина 2013; 6: 71-8).</mixed-citation><mixed-citation xml:lang="en">Smirnova MI, Gorbunov VM, Boytsov SA et al. Seasonal changes in hemodynamic parameters in patients with controlled hypertension and high normal blood pressure in two Russian regions with different climatic characteristics. Part 1: Design and preliminary results. Profilakticheskaya Meditcina 2013; 6: 71-8. In Russian (Смирнова М.И., Горбунов В.М., Бойцов С.А. и др. Сезонные изменения гемодинамических параметров у больных с контролируемой артериальной гипертонией и высоким нормальным артериальным давлением в двух регионах Российской Федерации с различными климатическими характеристиками. Часть 1. Дизайн и предварительные результаты. Профилактическая Медицина 2013; 6: 71-8).</mixed-citation></citation-alternatives></ref><ref id="cit21"><label>21</label><citation-alternatives><mixed-citation xml:lang="ru">Smirnova MI, Gorbunov VM, Volkov DA et al. Seasonal changes in hemodynamic parameters in patients with controlled hypertension and high normal blood pressure in two Russian regions with different climatic characteristics. Part 2. The main results of the study in 1423 patients. Profilakticheskaya Meditcina 2014; 6: 32-8. In Russian (Смирнова М.И., Горбунов В.М., Волков Д.А. и др. Сезонные изменения гемодинамических параметров у больных с контролируемой артериальной гипертонией и высоким нормальным артериальным давлением в двух регионах Российской Федерации с различными климатическими характеристиками. Часть 2. Основные результаты исследования 1423 пациентов. Профилактическая Медицина 2014; 6: 32-8.</mixed-citation><mixed-citation xml:lang="en">Smirnova MI, Gorbunov VM, Volkov DA et al. Seasonal changes in hemodynamic parameters in patients with controlled hypertension and high normal blood pressure in two Russian regions with different climatic characteristics. Part 2. The main results of the study in 1423 patients. Profilakticheskaya Meditcina 2014; 6: 32-8. In Russian (Смирнова М.И., Горбунов В.М., Волков Д.А. и др. Сезонные изменения гемодинамических параметров у больных с контролируемой артериальной гипертонией и высоким нормальным артериальным давлением в двух регионах Российской Федерации с различными климатическими характеристиками. Часть 2. Основные результаты исследования 1423 пациентов. Профилактическая Медицина 2014; 6: 32-8.</mixed-citation></citation-alternatives></ref><ref id="cit22"><label>22</label><citation-alternatives><mixed-citation xml:lang="ru">Hopstock LA, Wilsgaard T, Njølstad I, et al. Seasonal variation in incidence of acute myocardial infarction in a sub-Arctic population: The Tromsø Study 1974-2004. Eur J Cardiovasc Prev Rehabil 2011;18: 320-5.</mixed-citation><mixed-citation xml:lang="en">Hopstock LA, Wilsgaard T, Njølstad I, et al. Seasonal variation in incidence of acute myocardial infarction in a sub-Arctic population: The Tromsø Study 1974-2004. Eur J Cardiovasc Prev Rehabil 2011;18: 320-5.</mixed-citation></citation-alternatives></ref><ref id="cit23"><label>23</label><citation-alternatives><mixed-citation xml:lang="ru">Manfredini R, Manfredini F, Boari B, et al. Seasonal and weekly patterns of hospital admissions for nonfatal and fatal myocardial infarction. Am J Emerg Med 2009;27:1097-103.</mixed-citation><mixed-citation xml:lang="en">Manfredini R, Manfredini F, Boari B, et al. Seasonal and weekly patterns of hospital admissions for nonfatal and fatal myocardial infarction. Am J Emerg Med 2009;27:1097-103.</mixed-citation></citation-alternatives></ref><ref id="cit24"><label>24</label><citation-alternatives><mixed-citation xml:lang="ru">Kriszbacher I, Bódis J, Csoboth I, Boncz I. The occurrence of acute myocardial infarction in relation to weather conditions. Int J Cardiol 2009;135:136-8.</mixed-citation><mixed-citation xml:lang="en">Kriszbacher I, Bódis J, Csoboth I, Boncz I. The occurrence of acute myocardial infarction in relation to weather conditions. Int J Cardiol 2009;135:136-8.</mixed-citation></citation-alternatives></ref><ref id="cit25"><label>25</label><citation-alternatives><mixed-citation xml:lang="ru">Fischer T, Lundbye-Christensen S, Johnsen SP et al.. Secular trends and seasonality in first-time hospitalization for acute myocardial infarction: A Danish population-based study. Int J Cardiol 2004;97:425-31.</mixed-citation><mixed-citation xml:lang="en">Fischer T, Lundbye-Christensen S, Johnsen SP et al.. Secular trends and seasonality in first-time hospitalization for acute myocardial infarction: A Danish population-based study. Int J Cardiol 2004;97:425-31.</mixed-citation></citation-alternatives></ref><ref id="cit26"><label>26</label><citation-alternatives><mixed-citation xml:lang="ru">Rybak O.K., Burlaka A.N., Ivannikova N.P., Burlaka A.P. Influence of season pattern on prevalence and severity of acute myocardial infarction, function of hemostasis in patients with ischemic heart disease of climate area of middle Volga region. Saratovskiy Nauchno-Meditsinskiy Zhurnal 2007;3:68-72. In Russian (Рыбак О.К., Бурлака А.Н., Иванникова Н. П. Влияние сезона года на частоту развития и тяжесть течения острого инфаркта миокарда, особенности функционирования системы гемостаза у больных ишемической болезнью сердца в климатической зоне среднего Поволжья. Саратовский Научно-Медицинский Журнал 2007;3:68-72)</mixed-citation><mixed-citation xml:lang="en">Rybak O.K., Burlaka A.N., Ivannikova N.P., Burlaka A.P. Influence of season pattern on prevalence and severity of acute myocardial infarction, function of hemostasis in patients with ischemic heart disease of climate area of middle Volga region. Saratovskiy Nauchno-Meditsinskiy Zhurnal 2007;3:68-72. In Russian (Рыбак О.К., Бурлака А.Н., Иванникова Н. П. Влияние сезона года на частоту развития и тяжесть течения острого инфаркта миокарда, особенности функционирования системы гемостаза у больных ишемической болезнью сердца в климатической зоне среднего Поволжья. Саратовский Научно-Медицинский Журнал 2007;3:68-72)</mixed-citation></citation-alternatives></ref><ref id="cit27"><label>27</label><citation-alternatives><mixed-citation xml:lang="ru">Myint PK, Vowler SL, Woodhouse PR et al. Winter excess in hospital admissions, in-patient mortality and length of acute hospital stay in stroke: A hospital database study over six seasonal years in Norfolk, UK. Neuroepidemiology 2007;28:79-85.</mixed-citation><mixed-citation xml:lang="en">Myint PK, Vowler SL, Woodhouse PR et al. Winter excess in hospital admissions, in-patient mortality and length of acute hospital stay in stroke: A hospital database study over six seasonal years in Norfolk, UK. Neuroepidemiology 2007;28:79-85.</mixed-citation></citation-alternatives></ref><ref id="cit28"><label>28</label><citation-alternatives><mixed-citation xml:lang="ru">Frost L, Vukelic Andersen L, Mortensen LS et al. Seasonal variation in stroke and stroke-associated mortality in patients with a hospital diagnosis of nonvalvular atrial fibrillation or flutter. A population-based study in Denmark. Neuroepidemiology 2006;26:220-5.</mixed-citation><mixed-citation xml:lang="en">Frost L, Vukelic Andersen L, Mortensen LS et al. Seasonal variation in stroke and stroke-associated mortality in patients with a hospital diagnosis of nonvalvular atrial fibrillation or flutter. A population-based study in Denmark. Neuroepidemiology 2006;26:220-5.</mixed-citation></citation-alternatives></ref><ref id="cit29"><label>29</label><citation-alternatives><mixed-citation xml:lang="ru">Turin TC, Kita Y, Rumana N, et al. Stroke case fatality shows seasonal variation regardless of risk factor status in a Japanese population: 15-year results from the Takashima Stroke Registry. Neuroepidemiology 2009;32:53-60.</mixed-citation><mixed-citation xml:lang="en">Turin TC, Kita Y, Rumana N, et al. Stroke case fatality shows seasonal variation regardless of risk factor status in a Japanese population: 15-year results from the Takashima Stroke Registry. Neuroepidemiology 2009;32:53-60.</mixed-citation></citation-alternatives></ref><ref id="cit30"><label>30</label><citation-alternatives><mixed-citation xml:lang="ru">Karagiannis A, Tziomalos K, Mikhailidis DP et al. Seasonal variation in the occurrence of stroke in Northern Greece: A 10 year study in 8204 patients. Neurol Res 2010;32:326-31.</mixed-citation><mixed-citation xml:lang="en">Karagiannis A, Tziomalos K, Mikhailidis DP et al. Seasonal variation in the occurrence of stroke in Northern Greece: A 10 year study in 8204 patients. Neurol Res 2010;32:326-31.</mixed-citation></citation-alternatives></ref><ref id="cit31"><label>31</label><citation-alternatives><mixed-citation xml:lang="ru">Lee HC, Hu CJ, Chen CS, Lin HC. Seasonal variation in ischemic stroke incidence and association with climate: A six-year population-based study. Chronobiol Int 2008;25:938-49.</mixed-citation><mixed-citation xml:lang="en">Lee HC, Hu CJ, Chen CS, Lin HC. Seasonal variation in ischemic stroke incidence and association with climate: A six-year population-based study. Chronobiol Int 2008;25:938-49.</mixed-citation></citation-alternatives></ref><ref id="cit32"><label>32</label><citation-alternatives><mixed-citation xml:lang="ru">Pell JP, Cobbe SM. Seasonal variations in coronary heart disease. QJM 1999;92:689-96.</mixed-citation><mixed-citation xml:lang="en">Pell JP, Cobbe SM. Seasonal variations in coronary heart disease. QJM 1999;92:689-96.</mixed-citation></citation-alternatives></ref><ref id="cit33"><label>33</label><citation-alternatives><mixed-citation xml:lang="ru">Peters A, Dockery DW, Muller JE, Mittleman MA. Increased particulate air pollution and the triggering of myocardial infarction. Circulation 2001;103:2810-5.</mixed-citation><mixed-citation xml:lang="en">Peters A, Dockery DW, Muller JE, Mittleman MA. Increased particulate air pollution and the triggering of myocardial infarction. Circulation 2001;103:2810-5.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
