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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">rpcardio</journal-id><journal-title-group><journal-title xml:lang="en">Rational Pharmacotherapy in Cardiology</journal-title><trans-title-group xml:lang="ru"><trans-title>Рациональная Фармакотерапия в Кардиологии</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1819-6446</issn><issn pub-type="epub">2225-3653</issn><publisher><publisher-name>«SILICEA-POLIGRAF» LLC</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.20996/1819-6446-2012-8-2-201-204</article-id><article-id custom-type="elpub" pub-id-type="custom">rpcardio-559</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>NOTES FROM PRACTICE</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>КЛИНИЧЕСКИЙ ОПЫТ</subject></subj-group></article-categories><title-group><article-title>TELMISARTAN IN THE TREATMENT OF ARTERIAL HYPERTENSION. CASE STUDY</article-title><trans-title-group xml:lang="ru"><trans-title>ТЕЛМИСАРТАН В ЛЕЧЕНИИ АРТЕРИАЛЬНОЙ ГИПЕРТЕНЗИИ КЛИНИЧЕСКИЙ РАЗБОР</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Подзолков</surname><given-names>В. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Podzolkov</surname><given-names>V. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>профессор, д.м.н., заведующий кафедрой факультетской терапии №2 лечебного факультета</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Тарзиманова</surname><given-names>А. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Tarzimanova</surname><given-names>A. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>к.м.н., доцент кафедры факультетской терапии №2 лечебного факультета</p></bio><email xlink:type="simple">tarzimanova@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Первый Московский Государственный Медицинский Университет им. И.М. Сеченова</institution><country>Россия</country></aff><aff xml:lang="en"><institution>I.M. Setchenov First Moscow State Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2012</year></pub-date><pub-date pub-type="epub"><day>03</day><month>01</month><year>2016</year></pub-date><volume>8</volume><issue>2</issue><fpage>201</fpage><lpage>204</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Podzolkov V.I., Tarzimanova A.I., 2015</copyright-statement><copyright-year>2015</copyright-year><copyright-holder xml:lang="ru">Подзолков В.И., Тарзиманова А.И.</copyright-holder><copyright-holder xml:lang="en">Podzolkov V.I., Tarzimanova A.I.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.rpcardio.online/jour/article/view/559">https://www.rpcardio.online/jour/article/view/559</self-uri><abstract><p>Data on angiotensin II receptor blockers, one of the main drug classes used in cardiology , are presented. The advantages of this drugs class are highlighted with the focus on telmisartan. Additionally clinical example of successful telmisartan application in patients with hypertension, high risk of cardiovascular complications, and obesity is presented.</p></abstract><trans-abstract xml:lang="ru"><p>Представлены данные о блокаторах рецепторов ангиотензина-II, которые являются одним из основных классов лекарственных препаратов, применяемых в кардиологии. Освещаются преимущества этой группы препаратов, при этом особое внимание уделено телмисартану. В дополнение представлен клинический пример успешного применения телмисартана у пациента с артериальной гипертензией, высоким риском осложнений и ожирением.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>блокаторы рецепторов ангиотензина-II</kwd><kwd>телмисартан</kwd><kwd>артериальная гипертензия</kwd></kwd-group><kwd-group xml:lang="en"><kwd>angiotensin II receptor blockers</kwd><kwd>telmisartan</kwd><kwd>arterial hypertension</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">ESH-ESC Guidelines Committee. 2007 guidelines for the management of arterial hypertension. J Hypertension 2007; 25: 1105–87.</mixed-citation><mixed-citation xml:lang="en">ESH-ESC Guidelines Committee. 2007 guidelines for the management of arterial hypertension. J Hypertension 2007; 25: 1105–87.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">National guidelines for diagnosis and treatment of hypertension (4th revision). Sistemye Gipertenzii 2010; (3) : 5-26. Национальные рекомендации по диагностике и лечению артериальной гипертонии (четвертый пересмотр). Системные гипертензии 2010; (3): 5-26.</mixed-citation><mixed-citation xml:lang="en">National guidelines for diagnosis and treatment of hypertension (4th revision). Sistemye Gipertenzii 2010; (3) : 5-26. Национальные рекомендации по диагностике и лечению артериальной гипертонии (четвертый пересмотр). Системные гипертензии 2010; (3): 5-26.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Mancia G. Tolerability and safety of telmisartan as monotherapy or combined with hydrochlorothiazide compared with placebo. Am J Hypertens 2002; 15 (Supp 1): A54</mixed-citation><mixed-citation xml:lang="en">Mancia G. Tolerability and safety of telmisartan as monotherapy or combined with hydrochlorothiazide compared with placebo. Am J Hypertens 2002; 15 (Supp 1): A54</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Chazova I.E., Ratova L.G. The first generation sartans: Is there a future? Sistemnye Gipertenzii 2010; (4): 5–9. Russian (Чазова И.Е., Ратова Л.Г . Первое поколение сартанов: есть ли перспективы? Системные Гипертензии 2010; (4): 25-28).</mixed-citation><mixed-citation xml:lang="en">Chazova I.E., Ratova L.G. The first generation sartans: Is there a future? Sistemnye Gipertenzii 2010; (4): 5–9. Russian (Чазова И.Е., Ратова Л.Г . Первое поколение сартанов: есть ли перспективы? Системные Гипертензии 2010; (4): 25-28).</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Stangier J, Su CA, Roth W. Pharmacokinetics of orally and intravenously administered telmisartan in healthy young and elderly volunteers and in hypertensive patients. J Int Med Res. 2000 Jul-Aug;28(4):149-67.</mixed-citation><mixed-citation xml:lang="en">Stangier J, Su CA, Roth W. Pharmacokinetics of orally and intravenously administered telmisartan in healthy young and elderly volunteers and in hypertensive patients. J Int Med Res. 2000 Jul-Aug;28(4):149-67.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">The ONTARGET investigators. Telmisartan, ramipril or both in patients at high risk for vascular events. N Engl J Med 2008; 358: 1547–59.</mixed-citation><mixed-citation xml:lang="en">The ONTARGET investigators. Telmisartan, ramipril or both in patients at high risk for vascular events. N Engl J Med 2008; 358: 1547–59.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">The TRANSCEND investigators. Effects of the angiotensin-receptor blocker telmisartan on cardiovascular events in high-risk patients intolerant to angiotensin-converting enzyme inhibitors: a randomized controlled trial. Lancet 2008, 372: 1174–83.</mixed-citation><mixed-citation xml:lang="en">The TRANSCEND investigators. Effects of the angiotensin-receptor blocker telmisartan on cardiovascular events in high-risk patients intolerant to angiotensin-converting enzyme inhibitors: a randomized controlled trial. Lancet 2008, 372: 1174–83.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Barnett AH, Bain SC, Bouter P et al. Diabetics exposed to telmisartan and enalapril study group. Angiotensin-receptor blockade versus converting-enzyme inhibition in type 2 diabetes and nephropathy. N Engl J Med 2004; 351 (19): 1952–61.</mixed-citation><mixed-citation xml:lang="en">Barnett AH, Bain SC, Bouter P et al. Diabetics exposed to telmisartan and enalapril study group. Angiotensin-receptor blockade versus converting-enzyme inhibition in type 2 diabetes and nephropathy. N Engl J Med 2004; 351 (19): 1952–61.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Galle J, Schwedhelm E, Pinnetti S et al. VIVALDI investigators. Antiproteinuric effects of angiotensin receptor blockers: telmisartan versus valsartan in hypertensive patients with type 2 diabetes mellitus and overt nephropathy. Nephrol Dial Transplant 2008; 23 (10): 3174–83.</mixed-citation><mixed-citation xml:lang="en">Galle J, Schwedhelm E, Pinnetti S et al. VIVALDI investigators. Antiproteinuric effects of angiotensin receptor blockers: telmisartan versus valsartan in hypertensive patients with type 2 diabetes mellitus and overt nephropathy. Nephrol Dial Transplant 2008; 23 (10): 3174–83.</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Prasad B, Ravi N, Asma K et al. Angiotensin receptor blockers for the reduction of proteinuria in diabetic patients with overt nephropathy: results from the AMADEO study. Vasc Health Risk Manag 2009; 5: 129–40.</mixed-citation><mixed-citation xml:lang="en">Prasad B, Ravi N, Asma K et al. Angiotensin receptor blockers for the reduction of proteinuria in diabetic patients with overt nephropathy: results from the AMADEO study. Vasc Health Risk Manag 2009; 5: 129–40.</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Makino H, Haneda M, Babazono T et al. The telmisartan renoprotective study from incipient nephropathy to overt nephropathy – rationale, study design, treatment plan and baseline characteristics of the incipient to overt: angiotensin ii receptor blocker , telmisartan, investigation on type 2 diabetic nephropathy (INNOVATION) Study. J Int Med Res 2005; 33: 677–86.</mixed-citation><mixed-citation xml:lang="en">Makino H, Haneda M, Babazono T et al. The telmisartan renoprotective study from incipient nephropathy to overt nephropathy – rationale, study design, treatment plan and baseline characteristics of the incipient to overt: angiotensin ii receptor blocker , telmisartan, investigation on type 2 diabetic nephropathy (INNOVATION) Study. J Int Med Res 2005; 33: 677–86.</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Kurtz T ., Klein U. Next generation multifunctional angiotensin receptor blockers. Hypertens Res 2009;32(10): 826–34.</mixed-citation><mixed-citation xml:lang="en">Kurtz T ., Klein U. Next generation multifunctional angiotensin receptor blockers. Hypertens Res 2009;32(10): 826–34.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
