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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">rpcardio</journal-id><journal-title-group><journal-title xml:lang="en">Rational Pharmacotherapy in Cardiology</journal-title><trans-title-group xml:lang="ru"><trans-title>Рациональная Фармакотерапия в Кардиологии</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1819-6446</issn><issn pub-type="epub">2225-3653</issn><publisher><publisher-name>«SILICEA-POLIGRAF» LLC</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.20996/1819-6446-2012-8-5-691-693</article-id><article-id custom-type="elpub" pub-id-type="custom">rpcardio-584</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>POINT OF VIEW</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ТОЧКА ЗРЕНИЯ</subject></subj-group></article-categories><title-group><article-title>LIPID-LOWERING EFFICACY OF ROSUVASTATIN COMPARED WITH OTHER STATINS</article-title><trans-title-group xml:lang="ru"><trans-title>ГИПОЛИПИДЕМИЧЕСКАЯ ЭФФЕКТИВНОСТЬ РОЗУВАСТАТИНА В СРАВНЕНИИ С ДРУГИМИ СТАТИНАМИ</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Мешков</surname><given-names>А. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Meshkov</surname><given-names>A. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>к.м.н., руководитель лаборатории молекулярной генетики</p></bio><email xlink:type="simple">meshkov@cardio.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Государственный научно-исследовательский центр профилактической медицины</institution><country>Россия</country></aff><aff xml:lang="en"><institution>State Research Center for Preventive Medicine</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2012</year></pub-date><pub-date pub-type="epub"><day>06</day><month>01</month><year>2016</year></pub-date><volume>8</volume><issue>5</issue><fpage>691</fpage><lpage>693</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Meshkov A.N., 2015</copyright-statement><copyright-year>2015</copyright-year><copyright-holder xml:lang="ru">Мешков А.Н.</copyright-holder><copyright-holder xml:lang="en">Meshkov A.N.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.rpcardio.online/jour/article/view/584">https://www.rpcardio.online/jour/article/view/584</self-uri><abstract><p>Assessment of lipid-lowering effect of rosuvastatin is presented, as well as the main results of the study of rosuvastatin therapy efficacy , in comparison with other statins, received in controlled clinical trials of the GALAXY program: COMETS, LUNAR, MERCURY-I, SOLAR, STELLAR.</p></abstract><trans-abstract xml:lang="ru"><p>Дана оценка гиполипидемического действия розувастатина и представлены основные результаты изучения эффективности терапии розувастатином в сравнении с другими статинами, полученные в контролируемых клинических исследованиях, таких как COMETS, LUNAR, MERCURY-I, SOLAR, STELLAR, входящих в программу GALAXY .</p></trans-abstract><kwd-group xml:lang="ru"><kwd>статины</kwd><kwd>розувастатин</kwd><kwd>рандомизированные контролируемые исследования</kwd></kwd-group><kwd-group xml:lang="en"><kwd>statins</kwd><kwd>rosuvastatin</kwd><kwd>randomized controlled study</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Kannel W.B. Contributions of the Framingham Study to the conquest of coronary artery disease. Am J Cardiol 1988; 62: 1109–1112.</mixed-citation><mixed-citation xml:lang="en">Kannel W.B. Contributions of the Framingham Study to the conquest of coronary artery disease. Am J Cardiol 1988; 62: 1109–1112.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Wilson P .W.F ., D’Agostino R.B., Levy D., et al. Prediction of coronary heart disease using risk factor categories. Circulation 1998;97(18):1837–47.</mixed-citation><mixed-citation xml:lang="en">Wilson P .W.F ., D’Agostino R.B., Levy D., et al. Prediction of coronary heart disease using risk factor categories. Circulation 1998;97(18):1837–47.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Scandinavian Simvastatin Survival Study Group: Randomized trial of cholesterol lowering in 4,444 patients with coronary heart disease: the Scandinavian Simvastatin Survival Study (4S). Lancet 1994; 344: 1383–1389.</mixed-citation><mixed-citation xml:lang="en">Scandinavian Simvastatin Survival Study Group: Randomized trial of cholesterol lowering in 4,444 patients with coronary heart disease: the Scandinavian Simvastatin Survival Study (4S). Lancet 1994; 344: 1383–1389.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Sacks F .M., Pfeffer M.A., Moyи L.A., et al. The effect of pravastatin on coronary events after myocardial infarction in patients with average cholesterol levels. N Engl J Med 1996; 336: 1001–1009.</mixed-citation><mixed-citation xml:lang="en">Sacks F .M., Pfeffer M.A., Moyи L.A., et al. The effect of pravastatin on coronary events after myocardial infarction in patients with average cholesterol levels. N Engl J Med 1996; 336: 1001–1009.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Downs J.R., Clearfield M., Weis S., et al. Primary prevention of acute coronary events with lovastatin in men and women with average cholesterol levels. JAMA 1998; 279:1615–1622.</mixed-citation><mixed-citation xml:lang="en">Downs J.R., Clearfield M., Weis S., et al. Primary prevention of acute coronary events with lovastatin in men and women with average cholesterol levels. JAMA 1998; 279:1615–1622.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Combating major diseases in Europe — current problems and their solutions WHO Fact Sheet WHO EURO / 03/06. Available at: http://www.med.by/who/2006/fs0306r .pdf. Date of access: 10/10/2012. Russian (Борьба с основными болезнями в Европе – актуальные проблемы и пути их решения ВОЗ, Факты и цифры ЕРБ ВОЗ/03/06. Доступно на: http://www.med.by/who/2006/fs0306r .pdf. Дата доступа: 10/10/2012).</mixed-citation><mixed-citation xml:lang="en">Combating major diseases in Europe — current problems and their solutions WHO Fact Sheet WHO EURO / 03/06. Available at: http://www.med.by/who/2006/fs0306r .pdf. Date of access: 10/10/2012. Russian (Борьба с основными болезнями в Европе – актуальные проблемы и пути их решения ВОЗ, Факты и цифры ЕРБ ВОЗ/03/06. Доступно на: http://www.med.by/who/2006/fs0306r .pdf. Дата доступа: 10/10/2012).</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Kharchenko V.I., Kakorina E.P ., Koryakin M.V. et al. Mortality from cardiovascular diseases in Russia and developed countries. The need to strengthen cardiac services and modernization of medical statistics in the Russian Federation. Rossiyskiy Kardiologicheskiy Zhurnal 2005; (2): 3–9.Харченко В.И., Какорина Е.П., Корякин М.В. и соавт. Смертность от болезней системы кровообращения в России и экономически развитых странах. Необходимость усиления кардиологической службы и модернизации медицинской статистики в Российской Федерации. Российский Кардиологический Журнал 2005; (2): 3–9.</mixed-citation><mixed-citation xml:lang="en">Kharchenko V.I., Kakorina E.P ., Koryakin M.V. et al. Mortality from cardiovascular diseases in Russia and developed countries. The need to strengthen cardiac services and modernization of medical statistics in the Russian Federation. Rossiyskiy Kardiologicheskiy Zhurnal 2005; (2): 3–9.Харченко В.И., Какорина Е.П., Корякин М.В. и соавт. Смертность от болезней системы кровообращения в России и экономически развитых странах. Необходимость усиления кардиологической службы и модернизации медицинской статистики в Российской Федерации. Российский Кардиологический Журнал 2005; (2): 3–9.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Boitsov S., Khomitskaya Y .U.V. Results of centralized pan-Russian survey on the undertreatment of hypercholesterolemia (CEPHEUS). Eur Heart J 2012; 33 (Abstract Supplement): 451.</mixed-citation><mixed-citation xml:lang="en">Boitsov S., Khomitskaya Y .U.V. Results of centralized pan-Russian survey on the undertreatment of hypercholesterolemia (CEPHEUS). Eur Heart J 2012; 33 (Abstract Supplement): 451.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Oganov R.G., Kukharchuk V.V., Arutyunov G.P .et al The continuing violations of lipid profile in patients with dyslipidemia treated with statins in clinical practice in the Russian Federation (the Russian part of the study DYSIS). Kardiovaskulyarnaya Terapiya i Profilaktika 2012; 11(4) 99–108. Russian (Оганов Р .Г ., Кухарчук В.В., Арутюнов Г .П. и др. Сохраняющиеся нарушения показателей липидного спектра у пациентов с дислипидемией, получающих статины, в реальной клинической практике в Российской Федерации (российская часть исследования DYSIS). Кардиоваскулярная Терапия и Профилактика 2012; 11(4) 99–108).</mixed-citation><mixed-citation xml:lang="en">Oganov R.G., Kukharchuk V.V., Arutyunov G.P .et al The continuing violations of lipid profile in patients with dyslipidemia treated with statins in clinical practice in the Russian Federation (the Russian part of the study DYSIS). Kardiovaskulyarnaya Terapiya i Profilaktika 2012; 11(4) 99–108. Russian (Оганов Р .Г ., Кухарчук В.В., Арутюнов Г .П. и др. Сохраняющиеся нарушения показателей липидного спектра у пациентов с дислипидемией, получающих статины, в реальной клинической практике в Российской Федерации (российская часть исследования DYSIS). Кардиоваскулярная Терапия и Профилактика 2012; 11(4) 99–108).</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Schuster H. The GALAXY Program: an update on studies investigating efficacy and tolerability of rosuvastatin for reducing cardiovascular risk. Expert Rev Cardiovasc Ther 2007;5(2):177–93.</mixed-citation><mixed-citation xml:lang="en">Schuster H. The GALAXY Program: an update on studies investigating efficacy and tolerability of rosuvastatin for reducing cardiovascular risk. Expert Rev Cardiovasc Ther 2007;5(2):177–93.</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Stalenhoef A.F ., Ballantyne C.M., Sarti C., et al. A comparative study with rosuvastatin in subjects with metabolic syndrome: results of the COMETS study. Eur Heart J 2005;26(24):2664–72.</mixed-citation><mixed-citation xml:lang="en">Stalenhoef A.F ., Ballantyne C.M., Sarti C., et al. A comparative study with rosuvastatin in subjects with metabolic syndrome: results of the COMETS study. Eur Heart J 2005;26(24):2664–72.</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Pitt B., Loscalzo J., Monyak J., et al. Comparison of lipid-modifying efficacy of rosuvastatin versus atorvastatin in patients with acute coronary syndrome (from the LUNAR study). Am J Cardiol 2012;109(9):1239–46.</mixed-citation><mixed-citation xml:lang="en">Pitt B., Loscalzo J., Monyak J., et al. Comparison of lipid-modifying efficacy of rosuvastatin versus atorvastatin in patients with acute coronary syndrome (from the LUNAR study). Am J Cardiol 2012;109(9):1239–46.</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Stender S., Schuster H., Barter P ., et al. Comparison of rosuvastatin with atorvastatin, simvastatin and pravastatin in achieving cholesterol goals and improving plasma lipids in hypercholesterolaemic patients with or without the metabolic syndrome in the MERCURY I trial. Diabetes Obes Metab 2005;7(4):430–8.</mixed-citation><mixed-citation xml:lang="en">Stender S., Schuster H., Barter P ., et al. Comparison of rosuvastatin with atorvastatin, simvastatin and pravastatin in achieving cholesterol goals and improving plasma lipids in hypercholesterolaemic patients with or without the metabolic syndrome in the MERCURY I trial. Diabetes Obes Metab 2005;7(4):430–8.</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Insull W. Jr ., Ghali J.K., Hassman D.R., et al.; SOLAR Study Group. Achieving low-density lipoprotein cholesterol goals in high-risk patients in managed care: comparison of rosuvastatin, atorvastatin, and simvastatin in the SOLAR trial. Mayo Clin Proc 2007;82(5):543–50.</mixed-citation><mixed-citation xml:lang="en">Insull W. Jr ., Ghali J.K., Hassman D.R., et al.; SOLAR Study Group. Achieving low-density lipoprotein cholesterol goals in high-risk patients in managed care: comparison of rosuvastatin, atorvastatin, and simvastatin in the SOLAR trial. Mayo Clin Proc 2007;82(5):543–50.</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">McKenney J.M., Jones P .H., Adamczyk M.A., et al. Comparison of the efficacy of rosuvastatin versus atorvastatin, simvastatin, and pravastatin in achieving lipid goals: results from the STELLAR trial. Curr Med Res Opin 2003;19(8):689–98.</mixed-citation><mixed-citation xml:lang="en">McKenney J.M., Jones P .H., Adamczyk M.A., et al. Comparison of the efficacy of rosuvastatin versus atorvastatin, simvastatin, and pravastatin in achieving lipid goals: results from the STELLAR trial. Curr Med Res Opin 2003;19(8):689–98.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
