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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">rpcardio</journal-id><journal-title-group><journal-title xml:lang="en">Rational Pharmacotherapy in Cardiology</journal-title><trans-title-group xml:lang="ru"><trans-title>Рациональная Фармакотерапия в Кардиологии</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1819-6446</issn><issn pub-type="epub">2225-3653</issn><publisher><publisher-name>«SILICEA-POLIGRAF» LLC</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.20996/1819-6446-2009-5-2-89-97</article-id><article-id custom-type="elpub" pub-id-type="custom">rpcardio-648</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>POINT OF VIEW</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ТОЧКА ЗРЕНИЯ</subject></subj-group></article-categories><title-group><article-title>INNOVATIVE ANTIHYPERTENSIVE THERAPY IN THE LIGHT OF COMPLETED CLINICAL TRIALS</article-title><trans-title-group xml:lang="ru"><trans-title>ИННОВАЦИОННАЯ АНТИГИПЕРТЕНЗИВНАЯ ТЕРАПИЯ В СВЕТЕ ЗАВЕРШЕННЫХ НАУЧНЫХ ИССЛЕДОВАНИЙ</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Николаев</surname><given-names>Н. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Nikolaev</surname><given-names>N. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>644043 Омск, ул. Ленина, 12 </p></bio><bio xml:lang="en"><p>Lenina ul. 12, Omsk, 644043</p></bio><email xlink:type="simple">niknik.67@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Омская государственная медицинская академия</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Omsk State Medical Academy</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2009</year></pub-date><pub-date pub-type="epub"><day>09</day><month>01</month><year>2016</year></pub-date><volume>5</volume><issue>2</issue><fpage>89</fpage><lpage>97</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Nikolaev N.A., 2016</copyright-statement><copyright-year>2016</copyright-year><copyright-holder xml:lang="ru">Николаев Н.А.</copyright-holder><copyright-holder xml:lang="en">Nikolaev N.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.rpcardio.online/jour/article/view/648">https://www.rpcardio.online/jour/article/view/648</self-uri><abstract><p>The innovative approaches to antihypertensive pharmacotherapy and advantages of modern antihypertensive drugs are discussed on the basis of randomized controlled trial. The recommendations for usage of different class of antihypertensive drugs including their combinations are presented.</p></abstract><trans-abstract xml:lang="ru"><p>Обсуждаются инновационные подходы к антигипертензивной фармакотерапии и преимущества современных препаратов на основе результатов рандомизированных контролируемых исследований. Обобщены рекомендации для применения препаратов различных групп, в том числе в виде комбинаций.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>инновационная фармакотерапия</kwd><kwd>антигипертензивные препараты</kwd><kwd>артериальная гипертония</kwd></kwd-group><kwd-group xml:lang="en"><kwd>innovative pharmacotherapy</kwd><kwd>antihypertensive drugs</kwd><kwd>arterial hypertension</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Bhatt D.L., Steg P.G., Ohman E.M. et al. 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