<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.3 20210610//EN" "JATS-journalpublishing1-3.dtd">
<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">rpcardio</journal-id><journal-title-group><journal-title xml:lang="en">Rational Pharmacotherapy in Cardiology</journal-title><trans-title-group xml:lang="ru"><trans-title>Рациональная Фармакотерапия в Кардиологии</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1819-6446</issn><issn pub-type="epub">2225-3653</issn><publisher><publisher-name>«SILICEA-POLIGRAF» LLC</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.20996/1819-6446-2011-7-1-57-64</article-id><article-id custom-type="elpub" pub-id-type="custom">rpcardio-695</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>POINT OF VIEW</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ТОЧКА ЗРЕНИЯ</subject></subj-group></article-categories><title-group><article-title>ATRIAL FLUTTER: CONTEMPORARY POSSIBILITIES OF DIAGNOSIS AND TREATMENT</article-title><trans-title-group xml:lang="ru"><trans-title>ТРЕПЕТАНИЕ ПРЕДСЕРДИЙ: СОВРЕМЕННЫЕ ВОЗМОЖНОСТИ ДИАГНОСТИКИ И ЛЕЧЕНИЯ</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Бунин</surname><given-names>Ю. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Bunin</surname><given-names>Yu. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>д.м.н., профессор кафедры кардиологии</p></bio><email xlink:type="simple">yabunin@rol.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Российская медицинская академия последипломного образования</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Russian Medical Academy of Postgraduate Education</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2011</year></pub-date><pub-date pub-type="epub"><day>10</day><month>01</month><year>2016</year></pub-date><volume>7</volume><issue>1</issue><fpage>57</fpage><lpage>64</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Bunin Y.A., 2016</copyright-statement><copyright-year>2016</copyright-year><copyright-holder xml:lang="ru">Бунин Ю.А.</copyright-holder><copyright-holder xml:lang="en">Bunin Y.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.rpcardio.online/jour/article/view/695">https://www.rpcardio.online/jour/article/view/695</self-uri><abstract><p>Diagnosis and treatment of atrial flutter (AF) is an important clinical task. Epidemiological data, electrophysiological mechanisms and updated classification of AF are presented as well as treatment algorithm that is suggested by leading experts. Two strategies of AF therapy are shown: "rhythm control" and "rate control". Author paid attention that ventricular rate reduction in AF is more difficult task than this in atrial fibrillation. Indications for different AF treatments are discussed: pharmacotherapy, pacing and cardioversion as well as surgical methods.</p></abstract><trans-abstract xml:lang="ru"><p>Диагностика и лечение трепетания предсердий (ТП) является актуальной проблемой. Представлены данные эпидемиологии, электрофизиологические механизмы и современная классификация ТП, алгоритм лечения, который предложен ведущими экспертами. Показано, что в лечении ТП, как и при лечении фибрилляции предсердий (ФП), можно выделить 2 стратегии: «контроль ритма» и «контроль частоты». Отмечено, что снижение частоты желудочковых сокращений у больных с ТП, значительно труднее, чем при ФП. Описаны показания к различным видам терапии ТП: фармакологической терапии, электрокардиостимуляции и электроимпульсной терапии, а также к хирургическим методам лечения.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>трепетание предсердий</kwd><kwd>диагностика</kwd><kwd>лечение</kwd></kwd-group><kwd-group xml:lang="en"><kwd>atrial flutter</kwd><kwd>diagnosis</kwd><kwd>treatment</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">ACC/AHA/ESC guidelines for the management of patients with supraventricular arrhythmias--executive summary. J Am Coll Cardiol 2003;42(8):1493-531.</mixed-citation><mixed-citation xml:lang="en">ACC/AHA/ESC guidelines for the management of patients with supraventricular arrhythmias--executive summary. J Am Coll Cardiol 2003;42(8):1493-531.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Bialy D., Lehmann M.H., Schumacher D.N. et al. Hospitalization for arrhythmias in the United States: importance of atrial fibrillation (abstr). J Am Coll Cardiol 1992; 19: 41A.</mixed-citation><mixed-citation xml:lang="en">Bialy D., Lehmann M.H., Schumacher D.N. et al. Hospitalization for arrhythmias in the United States: importance of atrial fibrillation (abstr). J Am Coll Cardiol 1992; 19: 41A.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Granada J., Uribe W., Chyou P.H. et al. Incidence and predictor of atrial flutter in general population. J Am Coll Cardiol 2000; 36(7): 2242-2246.</mixed-citation><mixed-citation xml:lang="en">Granada J., Uribe W., Chyou P.H. et al. Incidence and predictor of atrial flutter in general population. J Am Coll Cardiol 2000; 36(7): 2242-2246.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Lee K.W., Yang Y., Scheinman M.M. Atrial flutter: a review of its history, mechanisms, clinical features and current therapy. Curr Probl Cardiol 2005;30(3):121-67.</mixed-citation><mixed-citation xml:lang="en">Lee K.W., Yang Y., Scheinman M.M. Atrial flutter: a review of its history, mechanisms, clinical features and current therapy. Curr Probl Cardiol 2005;30(3):121-67.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Vidaillet H., Granada J.F., Chyou P.H. et al. A population-based of mortality among patients with atrial fibrillation or flutter. Am J Med 2002; 113(5): 365-370.</mixed-citation><mixed-citation xml:lang="en">Vidaillet H., Granada J.F., Chyou P.H. et al. A population-based of mortality among patients with atrial fibrillation or flutter. Am J Med 2002; 113(5): 365-370.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Scheinman M.M., Yang Y., Cheng J. Atrial flutter: part II. Nomenclature. Pacing Clin Electrophysiol 2004; 27(4): 504-506.</mixed-citation><mixed-citation xml:lang="en">Scheinman M.M., Yang Y., Cheng J. Atrial flutter: part II. Nomenclature. Pacing Clin Electrophysiol 2004; 27(4): 504-506.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Nakagawa H., Shah N., Matsudaira K. et al. Characterization of reentrant circuit in macroreentrant right atrial tachycardia after surgical repair of congential heart disease. Circulation 2001; 103(5): 699-709.</mixed-citation><mixed-citation xml:lang="en">Nakagawa H., Shah N., Matsudaira K. et al. Characterization of reentrant circuit in macroreentrant right atrial tachycardia after surgical repair of congential heart disease. Circulation 2001; 103(5): 699-709.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Jais P., Shah D.C., Haissaguerre M. et al. Mapping and ablation of left atrial flutters. Circulation 2000; 101(25): 2928-2934.</mixed-citation><mixed-citation xml:lang="en">Jais P., Shah D.C., Haissaguerre M. et al. Mapping and ablation of left atrial flutters. Circulation 2000; 101(25): 2928-2934.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Kastor J.A., eds. Arrhythmias. Philadelphia: W.B. Saunders company;1994.p. 105-115.</mixed-citation><mixed-citation xml:lang="en">Kastor J.A., eds. Arrhythmias. Philadelphia: W.B. Saunders company;1994.p. 105-115.</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Schreck D.M., Rivera A.R., Tricarico V.J. Emergency management of atrial fibrillation and flutter: intravenous diltiazem versus intravenous digoxin. Ann Emerg Med 1997; 29(1): 135-140.</mixed-citation><mixed-citation xml:lang="en">Schreck D.M., Rivera A.R., Tricarico V.J. Emergency management of atrial fibrillation and flutter: intravenous diltiazem versus intravenous digoxin. Ann Emerg Med 1997; 29(1): 135-140.</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Goldenberg I.F., Lewis W.R., Dias V.C. et al. Intravenous diltiazem for the treatment of patients with atrial fibrillation or flutter and moderate to severe congestive heart failure. Am J Cardiol 1994; 74(9): 884-889.</mixed-citation><mixed-citation xml:lang="en">Goldenberg I.F., Lewis W.R., Dias V.C. et al. Intravenous diltiazem for the treatment of patients with atrial fibrillation or flutter and moderate to severe congestive heart failure. Am J Cardiol 1994; 74(9): 884-889.</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Grijns H.J., Van Gelder I.C., Tieleman R.G. et al. Long-term outcome of electrical cardioversion in patients with chronic atrial flutter. Heart 1997; 77(1): 56-61.</mixed-citation><mixed-citation xml:lang="en">Grijns H.J., Van Gelder I.C., Tieleman R.G. et al. Long-term outcome of electrical cardioversion in patients with chronic atrial flutter. Heart 1997; 77(1): 56-61.</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Gallay P., Bertinchant J.P., Lehujeur C. et al. La stimylation transoesophagiennedans le traitement du flutter et de la tachysystolie auriculaire. Arch Mal Coeur 1985; 78(3): 311-316.</mixed-citation><mixed-citation xml:lang="en">Gallay P., Bertinchant J.P., Lehujeur C. et al. La stimylation transoesophagiennedans le traitement du flutter et de la tachysystolie auriculaire. Arch Mal Coeur 1985; 78(3): 311-316.</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Stambler B.S., Wood M.A., Ellenbogen K.A. Comparative efficacy of intravenous ibutilide versus procainamide for enhancing termination of atrial flutter by atrial overdrive pacing. Am J Cardiol 1996; 77(11): 960-966.</mixed-citation><mixed-citation xml:lang="en">Stambler B.S., Wood M.A., Ellenbogen K.A. Comparative efficacy of intravenous ibutilide versus procainamide for enhancing termination of atrial flutter by atrial overdrive pacing. Am J Cardiol 1996; 77(11): 960-966.</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">Doni F., Della Bella P., Kheir A. et al. Atrial flutter termination by overdrive trans-esophageal pacing and the facilitating effect of oral propafenone. Am J Cardiol 1995; 76(17): 1243-1246.</mixed-citation><mixed-citation xml:lang="en">Doni F., Della Bella P., Kheir A. et al. Atrial flutter termination by overdrive trans-esophageal pacing and the facilitating effect of oral propafenone. Am J Cardiol 1995; 76(17): 1243-1246.</mixed-citation></citation-alternatives></ref><ref id="cit16"><label>16</label><citation-alternatives><mixed-citation xml:lang="ru">Volgman A.S., Carberry P.A., Stambler B. et al. Conversion efficacy and safety on intravenous ibutilide compared with intravenous procainamide in patients with atrial flutter or fibrillation. J Am CollCardiol 1998; 31(6): 1414-1419.</mixed-citation><mixed-citation xml:lang="en">Volgman A.S., Carberry P.A., Stambler B. et al. Conversion efficacy and safety on intravenous ibutilide compared with intravenous procainamide in patients with atrial flutter or fibrillation. J Am CollCardiol 1998; 31(6): 1414-1419.</mixed-citation></citation-alternatives></ref><ref id="cit17"><label>17</label><citation-alternatives><mixed-citation xml:lang="ru">Vos M.A., Golitsyn S.R., Stangl K. et al. Superiority of ibutilide over DL-sotalol in converting atrial flutter and atrial fibrillation. Heart 1998; 79(6): 568-575.</mixed-citation><mixed-citation xml:lang="en">Vos M.A., Golitsyn S.R., Stangl K. et al. Superiority of ibutilide over DL-sotalol in converting atrial flutter and atrial fibrillation. Heart 1998; 79(6): 568-575.</mixed-citation></citation-alternatives></ref><ref id="cit18"><label>18</label><citation-alternatives><mixed-citation xml:lang="ru">Rosenshtraukh L.V., Ruda M.Ia., Golitsyn S.P., Maikov E.B. Novel antiarrhythmic class III drug nibentan: from experimental studies to clinical practice. Kardiologiia. 2003;43(6):66-8. Russian (Розенштраух Л.В., Руда М.Я., Голицин С.П., Майков Е.Б. Новый отечественный антиаритмический препарат III класса нибентан: от экспериментальных исследований к клинической практике. Кардиология 2003; 43: 66-68).</mixed-citation><mixed-citation xml:lang="en">Rosenshtraukh L.V., Ruda M.Ia., Golitsyn S.P., Maikov E.B. Novel antiarrhythmic class III drug nibentan: from experimental studies to clinical practice. Kardiologiia. 2003;43(6):66-8. Russian (Розенштраух Л.В., Руда М.Я., Голицин С.П., Майков Е.Б. Новый отечественный антиаритмический препарат III класса нибентан: от экспериментальных исследований к клинической практике. Кардиология 2003; 43: 66-68).</mixed-citation></citation-alternatives></ref><ref id="cit19"><label>19</label><citation-alternatives><mixed-citation xml:lang="ru">Singh S., Zoble R.G., Yellen L. et al. Efficacy and safety of oral dofetilide in converting to and maintaining sinus rhythm in patients with chronic atrial fibrillation of atrial flutter (SAFIRE-D study). Circulation 2000; 102(19): 2385-2390.</mixed-citation><mixed-citation xml:lang="en">Singh S., Zoble R.G., Yellen L. et al. Efficacy and safety of oral dofetilide in converting to and maintaining sinus rhythm in patients with chronic atrial fibrillation of atrial flutter (SAFIRE-D study). Circulation 2000; 102(19): 2385-2390.</mixed-citation></citation-alternatives></ref><ref id="cit20"><label>20</label><citation-alternatives><mixed-citation xml:lang="ru">Pedersen O.D., Bagger H., Keller N. et al. Efficacy of dofetilide in the treatment of atrial fibrillation-flutter with reduced left ventricular function (DIAMOND substudy). Circulation 2001; 104(3): 292-296.</mixed-citation><mixed-citation xml:lang="en">Pedersen O.D., Bagger H., Keller N. et al. Efficacy of dofetilide in the treatment of atrial fibrillation-flutter with reduced left ventricular function (DIAMOND substudy). Circulation 2001; 104(3): 292-296.</mixed-citation></citation-alternatives></ref><ref id="cit21"><label>21</label><citation-alternatives><mixed-citation xml:lang="ru">Schumacher B., Jung W., Lewalter T. et al. Radiofrequency ablation of atrial flutter due to administration of class IC antiarrhythmic drugs for atrial fibrillation. Am J Cardiol 1999; 83(5): 710-713.</mixed-citation><mixed-citation xml:lang="en">Schumacher B., Jung W., Lewalter T. et al. Radiofrequency ablation of atrial flutter due to administration of class IC antiarrhythmic drugs for atrial fibrillation. Am J Cardiol 1999; 83(5): 710-713.</mixed-citation></citation-alternatives></ref><ref id="cit22"><label>22</label><citation-alternatives><mixed-citation xml:lang="ru">Tai C.T., Chiang C.E., Lee S.H. et al. Persistent atrial flutter in patients treated for atrial fibrillation with amiodarone and propafenone. J Cardiovasc Electrophysiol 1999; 10(9): 1180-1187.</mixed-citation><mixed-citation xml:lang="en">Tai C.T., Chiang C.E., Lee S.H. et al. Persistent atrial flutter in patients treated for atrial fibrillation with amiodarone and propafenone. J Cardiovasc Electrophysiol 1999; 10(9): 1180-1187.</mixed-citation></citation-alternatives></ref><ref id="cit23"><label>23</label><citation-alternatives><mixed-citation xml:lang="ru">Bunin Yu.A., Fedyakina L.F. Combined preventive anti-arrhythmic pharmacotherapy of atrial fibrillation and flutter. Rossiyskiy kardiologicheskiy zhurnal 2006; 6: 35-45. Russian (Бунин Ю.А., Федякина Л.Ф. Комбинированная профилактическая антиаритмическая терапия фибрилляции и трепетания предсердий. Российский кардиологический журнал 2006; 6: 35-45).</mixed-citation><mixed-citation xml:lang="en">Bunin Yu.A., Fedyakina L.F. Combined preventive anti-arrhythmic pharmacotherapy of atrial fibrillation and flutter. Rossiyskiy kardiologicheskiy zhurnal 2006; 6: 35-45. Russian (Бунин Ю.А., Федякина Л.Ф. Комбинированная профилактическая антиаритмическая терапия фибрилляции и трепетания предсердий. Российский кардиологический журнал 2006; 6: 35-45).</mixed-citation></citation-alternatives></ref><ref id="cit24"><label>24</label><citation-alternatives><mixed-citation xml:lang="ru">Dunn M.I. Thromboembolism with atrial flutter. Am J Cardiol 1998; 82: 638.</mixed-citation><mixed-citation xml:lang="en">Dunn M.I. Thromboembolism with atrial flutter. Am J Cardiol 1998; 82: 638.</mixed-citation></citation-alternatives></ref><ref id="cit25"><label>25</label><citation-alternatives><mixed-citation xml:lang="ru">Seidl K., Hauer B., Schwick N.G. et al. Risk of thromboembolic events in patients with atrial flutter. Am J Cardiol 1998; 82(5): 580-583.</mixed-citation><mixed-citation xml:lang="en">Seidl K., Hauer B., Schwick N.G. et al. Risk of thromboembolic events in patients with atrial flutter. Am J Cardiol 1998; 82(5): 580-583.</mixed-citation></citation-alternatives></ref><ref id="cit26"><label>26</label><citation-alternatives><mixed-citation xml:lang="ru">Halligan S.C., Gersh B.J., Brown R.D. The natural history of lone atrial flutter. Ann Intern Med 2004; 140(4): 265-268.</mixed-citation><mixed-citation xml:lang="en">Halligan S.C., Gersh B.J., Brown R.D. The natural history of lone atrial flutter. Ann Intern Med 2004; 140(4): 265-268.</mixed-citation></citation-alternatives></ref><ref id="cit27"><label>27</label><citation-alternatives><mixed-citation xml:lang="ru">Feld G.K., Fleck R.P., Chen P.S. et al. Radiofrequency catheter ablation for the treatment of human type I atrial flutter. Circulation 1992; 86(4): 1233-1240.</mixed-citation><mixed-citation xml:lang="en">Feld G.K., Fleck R.P., Chen P.S. et al. Radiofrequency catheter ablation for the treatment of human type I atrial flutter. Circulation 1992; 86(4): 1233-1240.</mixed-citation></citation-alternatives></ref><ref id="cit28"><label>28</label><citation-alternatives><mixed-citation xml:lang="ru">Miller J.M., Zipes D.P. Therapy for cardiac arrhythmias. In: Braunwald E., Zipes D., LibbyP., Bonow R.,eds. Heart disease. A textbook of cardiovascular medicine. Philadelphia: W.B. Saunders company; 2005. p. 713-766.</mixed-citation><mixed-citation xml:lang="en">Miller J.M., Zipes D.P. Therapy for cardiac arrhythmias. In: Braunwald E., Zipes D., LibbyP., Bonow R.,eds. Heart disease. A textbook of cardiovascular medicine. Philadelphia: W.B. Saunders company; 2005. p. 713-766.</mixed-citation></citation-alternatives></ref><ref id="cit29"><label>29</label><citation-alternatives><mixed-citation xml:lang="ru">Rho R.W., Callans D.J. The management of atrial flutter. In:Ganz L.I., Braunwald E.,eds. Management of cardiac arrhythmias. NJ: Humana Press;2004. p. 163-182.</mixed-citation><mixed-citation xml:lang="en">Rho R.W., Callans D.J. The management of atrial flutter. In:Ganz L.I., Braunwald E.,eds. Management of cardiac arrhythmias. NJ: Humana Press;2004. p. 163-182.</mixed-citation></citation-alternatives></ref><ref id="cit30"><label>30</label><citation-alternatives><mixed-citation xml:lang="ru">Natale A., Newby K.H., Pisanу E.et al. Prospective randomized comparison of antiarrhythmic therapy versus first line radiofrequency ablation in patients with atrial flutter. J Am Coll Car-diol 2000; 35(7): 1898-1904.</mixed-citation><mixed-citation xml:lang="en">Natale A., Newby K.H., Pisanу E.et al. Prospective randomized comparison of antiarrhythmic therapy versus first line radiofrequency ablation in patients with atrial flutter. J Am Coll Car-diol 2000; 35(7): 1898-1904.</mixed-citation></citation-alternatives></ref><ref id="cit31"><label>31</label><citation-alternatives><mixed-citation xml:lang="ru">Da Costa A., Thevenin J., Roche F. et al. Results from the Loire-Ardeche-Drome-Isere-Puyde-Dome (LADIP) trial. Circulation 2006; 114(16): 1676-1681.</mixed-citation><mixed-citation xml:lang="en">Da Costa A., Thevenin J., Roche F. et al. Results from the Loire-Ardeche-Drome-Isere-Puyde-Dome (LADIP) trial. Circulation 2006; 114(16): 1676-1681.</mixed-citation></citation-alternatives></ref><ref id="cit32"><label>32</label><citation-alternatives><mixed-citation xml:lang="ru">Huang D.T., Monahan K.M., Zimetbaum P. et al. Hybrid pharmacologic and ablative therapy. J Cardiovasc Electrophysiol 1998;9(5):462-9.</mixed-citation><mixed-citation xml:lang="en">Huang D.T., Monahan K.M., Zimetbaum P. et al. Hybrid pharmacologic and ablative therapy. J Cardiovasc Electrophysiol 1998;9(5):462-9.</mixed-citation></citation-alternatives></ref><ref id="cit33"><label>33</label><citation-alternatives><mixed-citation xml:lang="ru">Scheinman M.M., Huang S. The 1998 NASPE prospective catheter ablation registry. Pacing Clin Electrophysiol 2000; 23(6): 1020-1028.</mixed-citation><mixed-citation xml:lang="en">Scheinman M.M., Huang S. The 1998 NASPE prospective catheter ablation registry. Pacing Clin Electrophysiol 2000; 23(6): 1020-1028.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
