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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">rpcardio</journal-id><journal-title-group><journal-title xml:lang="en">Rational Pharmacotherapy in Cardiology</journal-title><trans-title-group xml:lang="ru"><trans-title>Рациональная Фармакотерапия в Кардиологии</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1819-6446</issn><issn pub-type="epub">2225-3653</issn><publisher><publisher-name>«SILICEA-POLIGRAF» LLC</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.20996/1819-6446-2011-7-2-231-240</article-id><article-id custom-type="elpub" pub-id-type="custom">rpcardio-755</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>CURRENT QUESTIONS OF CLINICAL PHARMACOLOGY</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>АКТУАЛЬНЫЕ  ВОПРОСЫ  КЛИНИЧЕСКОЙ ФАРМАКОЛОГИИ</subject></subj-group></article-categories><title-group><article-title>LIPRIMAR®. FIFTEEN YEARS OF EVIDENCE</article-title><trans-title-group xml:lang="ru"><trans-title>ЛИПРИМАР®. ПЯТНАДЦАТЬ ЛЕТ УБЕДИТЕЛЬНЫХ ДОКАЗАТЕЛЬСТВ</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Сусеков</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Susekov</surname><given-names>A. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>д.м.н., в.н.с. отдела возрастных проблем сердечно-сосудистых заболеваний</p></bio><email xlink:type="simple">asus99@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Хохлова</surname><given-names>Н. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Khokhlova</surname><given-names>N. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>аспирант отдела возрастных проблем сердечно-сосудистых заболеваний</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Институт клинической кардиологии им. А.Л. Мясникова, Российский кардиологический научно-производственный комплекс</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Institute for Cardiology named after A.L. Mjasnikov , Russian Cardiology Research and Production Complex</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2011</year></pub-date><pub-date pub-type="epub"><day>14</day><month>01</month><year>2016</year></pub-date><volume>7</volume><issue>2</issue><fpage>231</fpage><lpage>240</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Susekov A.V., Khokhlova N.V., 2016</copyright-statement><copyright-year>2016</copyright-year><copyright-holder xml:lang="ru">Сусеков А.В., Хохлова Н.В.</copyright-holder><copyright-holder xml:lang="en">Susekov A.V., Khokhlova N.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.rpcardio.online/jour/article/view/755">https://www.rpcardio.online/jour/article/view/755</self-uri><abstract><p>The evidences for statin use in cardiology are presented. Especially hypolipidemic efficacy of atorvastatin is demonstrated in according to comparative studies. Results of clinical studies on atorvastatin efficacy and safety in different groups of patients are also presented.</p></abstract><trans-abstract xml:lang="ru"><p>Приводятся доказательства по применению статинов в кардиологии. Отдельно расcматривается гиполипидемическая эффективность аторвастатина, продемонстрированная в сравнительных исследованиях. Также приводятся клинические исследования эффективности и безопасности аторвастатина в различных группах больных.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>статины</kwd><kwd>аторвастатин</kwd><kwd>атеросклероз</kwd><kwd>клинические исследования</kwd></kwd-group><kwd-group xml:lang="en"><kwd>statins</kwd><kwd>atorvastatin</kwd><kwd>atherosclerosis</kwd><kwd>clinical trials</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults. Executive Summary of the Third Report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III). 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