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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">rpcardio</journal-id><journal-title-group><journal-title xml:lang="en">Rational Pharmacotherapy in Cardiology</journal-title><trans-title-group xml:lang="ru"><trans-title>Рациональная Фармакотерапия в Кардиологии</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1819-6446</issn><issn pub-type="epub">2225-3653</issn><publisher><publisher-name>«SILICEA-POLIGRAF» LLC</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.20996/1819-6446-2010-6-2-185-191</article-id><article-id custom-type="elpub" pub-id-type="custom">rpcardio-818</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>POINT OF VIEW</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ТОЧКА ЗРЕНИЯ</subject></subj-group></article-categories><title-group><article-title>THE MODERN ASPECTS OF CLOPIDOGREL USE</article-title><trans-title-group xml:lang="ru"><trans-title>СОВРЕМЕННЫЕ АСПЕКТЫ ПРИМЕНЕНИЯ КЛОПИДОГРЕЛА</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Данковцева</surname><given-names>Е. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Dankovtseva</surname><given-names>E. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>к.м.н., доцент кафедры кардиологии и общей терапии </p><p>121359 Москва, Маршала Тимошенко ул., 21</p></bio><bio xml:lang="en"><p>Marshall Timoshenko ul. 21, Moscow, 121359</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Затейщиков</surname><given-names>Д. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Zateyshchikov</surname><given-names>D. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>д.м.н., профессор кафедры кардиологии и общей терапии </p><p>121359 Москва, Маршала Тимошенко ул., 21</p></bio><bio xml:lang="en"><p>Marshall Timoshenko ul. 21, Moscow, 121359</p></bio><email xlink:type="simple">dz@bk.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Учебно-научный медицинский центр Управления делами Президента РФ</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Training and Research Medical Centre of Administrative Department of the President of the Russian Federation</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2010</year></pub-date><pub-date pub-type="epub"><day>18</day><month>01</month><year>2016</year></pub-date><volume>6</volume><issue>2</issue><fpage>185</fpage><lpage>191</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Dankovtseva E.N., Zateyshchikov D.A., 2016</copyright-statement><copyright-year>2016</copyright-year><copyright-holder xml:lang="ru">Данковцева Е.Н., Затейщиков Д.А.</copyright-holder><copyright-holder xml:lang="en">Dankovtseva E.N., Zateyshchikov D.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.rpcardio.online/jour/article/view/818">https://www.rpcardio.online/jour/article/view/818</self-uri><abstract><p>The possibilities and evidence base of clopidogrel use in clinical practice are discussed. Data about the main trails on clopidogrel efficacy in treatment and second prevention of atherothrombotic complications are presented. The results of the comparative trails of original and generic clopidogrel are also reviewed.</p></abstract><trans-abstract xml:lang="ru"><p>Рассматриваются возможности и доказательная база применения клопидогрела в клинической практике. Приводятся данные основных исследований по изучению эффективности клопидогрела при лечении и вторичной профилактике последствий атеротромбоза. Отдельно обсуждаются результаты сравнительных исследований оригинального и дженерического препаратов клопидогрела.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>клопидогрел</kwd><kwd>антитромбоцитарная терапия</kwd><kwd>инфаркт миокарда</kwd><kwd>дженерик</kwd></kwd-group><kwd-group xml:lang="en"><kwd>clopidogrel</kwd><kwd>antiplatelet therapy</kwd><kwd>myocardial infarction</kwd><kwd>generic</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">A randomised, blinded trial of clopidogrel versus aspirin in patients at risk of ischemic events (CAPRIE). The CAPRIE Steering Committee. Lancet 1996;348(9038):1329-39.</mixed-citation><mixed-citation xml:lang="en">A randomised, blinded trial of clopidogrel versus aspirin in patients at risk of ischemic events (CAPRIE). The CAPRIE Steering Committee. 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