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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">rpcardio</journal-id><journal-title-group><journal-title xml:lang="en">Rational Pharmacotherapy in Cardiology</journal-title><trans-title-group xml:lang="ru"><trans-title>Рациональная Фармакотерапия в Кардиологии</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1819-6446</issn><issn pub-type="epub">2225-3653</issn><publisher><publisher-name>«SILICEA-POLIGRAF» LLC</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.20996/1819-6446-2010-6-3-381-390</article-id><article-id custom-type="elpub" pub-id-type="custom">rpcardio-883</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>FROM THE JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ИЗ JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY</subject></subj-group></article-categories><title-group><article-title>BLUMENTHAL SCREENING FOR CARDIOVASCULAR RISK IN ASYMPTOMATIC PATIENTS</article-title><trans-title-group xml:lang="ru"><trans-title>СКРИНИНГ СЕРДЕЧНО-СОСУДИСТОГО РИСКА У БЕССИМПТОМНЫХ ПАЦИЕНТОВ</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Berger</surname><given-names>J. S.</given-names></name><name name-style="western" xml:lang="en"><surname>Berger</surname><given-names>J. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Department of Medicine, , L.H.Charney Division of Cardiovascular Medicine. New York, New York. &amp; Department of Medicine</p><p>Division of Cardiovascular Medicine. Philadelphia, Pennsylvania</p></bio><bio xml:lang="en"><p>Department of Medicine, L.H.Charney Division of Cardiovascular Medicine. New York, New York. &amp; Department of Medicine,</p><p>Division of Cardiovascular Medicine. Philadelphia, Pennsylvania</p></bio><email xlink:type="simple">jeffrey.berger@nyumc.or</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Jordan</surname><given-names>C. O.</given-names></name><name name-style="western" xml:lang="en"><surname>Jordan</surname><given-names>C. O.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Department of Medicine, Division of Cardiovascular Medicine. Minneapolis, Minnesota</p></bio><bio xml:lang="en"><p>Department of Medicine,</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Lloyd-Jones</surname><given-names>D.</given-names></name><name name-style="western" xml:lang="en"><surname>Lloyd-Jones</surname><given-names>D.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Departments of Preventive Medicine and Medicine</p></bio><bio xml:lang="en"><p>Departments of Preventive Medicine and Medicine</p></bio><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Blumenthal</surname><given-names>R.S.</given-names></name><name name-style="western" xml:lang="en"><surname>Blumenthal</surname><given-names>R.S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Department of Medicine</p></bio><bio xml:lang="en"><p>Department of Medicine</p></bio><xref ref-type="aff" rid="aff-4"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>New York University School of Medicine, &#13;
University of Pennsylvania</institution><country>Соединённые Штаты Америки</country></aff><aff xml:lang="en"><institution>New York University School of Medicine, &#13;
University of Pennsylvania</institution><country>United States</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>University of Minnesota</institution><country>Соединённые Штаты Америки</country></aff><aff xml:lang="en"><institution>University of Minnesota, Division of Cardiovascular Medicine. Minneapolis, Minnesota</institution><country>United States</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>Northwestern University, Feinberg School of Medicine. Chicago, Illinois</institution><country>Соединённые Штаты Америки</country></aff><aff xml:lang="en"><institution>Northwestern University, Feinberg School of Medicine. Chicago, Illinois</institution><country>United States</country></aff></aff-alternatives><aff-alternatives id="aff-4"><aff xml:lang="ru"><institution>J. Hopkins Ciccarone Center for the Prevention of Heart Disease. Baltimore, Maryland</institution><country>Соединённые Штаты Америки</country></aff><aff xml:lang="en"><institution>J. Hopkins Ciccarone Center for the Prevention of Heart Disease. Baltimore, Maryland</institution><country>United States</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2010</year></pub-date><pub-date pub-type="epub"><day>19</day><month>01</month><year>2016</year></pub-date><volume>6</volume><issue>3</issue><fpage>381</fpage><lpage>390</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Berger J.S., Jordan C.O., Lloyd-Jones D., Blumenthal R., 2016</copyright-statement><copyright-year>2016</copyright-year><copyright-holder xml:lang="ru">Berger J.S., Jordan C.O., Lloyd-Jones D., Blumenthal R.</copyright-holder><copyright-holder xml:lang="en">Berger J.S., Jordan C.O., Lloyd-Jones D., Blumenthal R.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.rpcardio.online/jour/article/view/883">https://www.rpcardio.online/jour/article/view/883</self-uri><abstract><p>Blumenthal screening for cardiovascular risk in asymptomatic patients.</p></abstract><trans-abstract xml:lang="ru"><p>Сердечно-сосудистые заболевания (ССЗ) — основная причина смертности в западных странах и одна из ведущих причин смертности в мире. Риск ССЗ, связанных с атеросклерозом в течение всей последующей жизни у лиц в возрасте 50 лет, в среднем составляет 52% для мужчин и 39% для женщин с большими различиями в зависимости от тяжести факторов риска. Оценка сердечно-сосудистого риска может быть полезна для целенаправленного выбора профилактического лечения пациентов, у которых нет симптомов, но достаточно высок риск ССЗ. Стратификация пациентов в соответствии с риском ССЗ остается сложной, особенно в случаях с низким или промежуточным краткосрочным риском. Для облегчения оценки индивидуального риска было предложено несколько алгоритмов. Представлено описание 6 алгоритмов оценки риска: Фремингемской шкалы оценки риска развития ишемической болезни сердца и сердечно-сосудистых заболеваний (Framingham Risk Score for coronary heart disease events and for cardiovascular events); III отчета группы экспертов по оценке и лечению гиперхолестеринемии у взрослых (Adult Treatment Panel III — ATP III); шкалы SCORE (Systematic COronary Risk Evaluation); шкалы риска Рейнольдса (Reynolds Risk Score); шкалы ASSIGN (Assessing Cardiovascular Risk to Scottish Intercollegiate Guidelines Network/SIGN to Assign Preventative Treatment); алгоритма QRISK (QRESEARCH Cardiovascular Risk Algorithm). Описание шкалы включает характеристику популяций, в которых она была разработана и проверена, факторы риска, используемые при оценке, прогнозируемые исходы, результаты ROC (receiveroperating characteristic) анализа и ограничения применения. К нерешенным проблемам при оценке сердечно-сосудистого риска относятся: преимущество оценки 10-летнего риска по сравнению с риском в течение всей последующей жизни; целесообразность прогнозирования конечных точек, связанных с ССЗ или только с коронарной болезнью сердца; эффективность применения шкал риска, из которых исключены лабораторные показатели; возраст, в котором надо начинать оценивать риск; влияние расовых и половых различий на оценку риска и вопрос о том, должна ли оценка риска определять терапию. Авторы считают, что наилучший подход к выявлению и профилактике высокого риска ССЗ заключается в рутинной практике тестирования сердечно-сосудистых факторов риска и оценки с применением шкал риска. Авторы рекомендуем работникам здравоохранения обсуждать суммарный кардиоваскулярный риск и оценку кардиоваскулярного риска в течение последующей жизни с каждым пациентом для лучшего понимания пациентом будущего риска. Адекватное вмешательство, основанное на оценке риска, имеет потенциал для значительного снижения уровня риска в популяции.</p><p>Перевод и публикация статьи осуществлены с разрешения American College of Cardiology и под контролем экспертов ВНОК.</p><p>Статья J.S. Berger, C.O. Jordan, D. Lloyd-Jones, R.S. Blumenthal Screening for Cardiovascular Risk in Asymptomatic Patients впервые опубликована в J Am Coll Cardiol 2010;55:1169–77 © 2010 by the American College of Cardiology Foundation.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>сердечно-сосудистое заболевание</kwd><kwd>шкала риска</kwd><kwd>профилактика</kwd><kwd>инфаркт миокарда</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Lloyd-Jones D, Adams R, Carnethon M, et al. 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