rpcardioRational Pharmacotherapy in CardiologyРациональная Фармакотерапия в Кардиологии1819-64462225-3653«SILICEA-POLIGRAF» LLC10.20996/1819-6446-2011-7-5-620-627rpcardio-937Research ArticlePOINT OF VIEWТОЧКА ЗРЕНИЯDIETARY FATTY ACIDS. EFFECTS ON THE RISK OF CARDIOVASCULAR DISEASESПИЩЕВЫЕ ЖИРНЫЕ КИСЛОТЫ. ВЛИЯНИЕ НА РИСК БОЛЕЗНЕЙ СИСТЕМЫ КРОВООБРАЩЕНИЯПероваН. В.PerovaN. V.

д.м.н., профессор, в.н.с. отдела изучения биохимических маркёров риска хронических неинфекционных заболеваний

nperova@gnicpm.ruМетельскаяВ. А.Metel'skayaV. A.

д.б.н., профессор, учёный секретарь

СоколовЕ. И.SokolovE. I.

д.м.н., профессор, академик РАМН, зав. кафедрой факультетской терапии и профессиональных болезней

ЩукинаГ. Н.ShchukinaG. N.

к.м.н., доцент кафедры факультетской терапии и профессиональных болезней

ФоминаВ. М.FominaV. M.

к.м.н., доцент кафедры факультетской терапии и профессиональных болезней

Государственный научно-исследовательский центр профилактической медициныРоссияState Research Center for Preventive MedicineRussian FederationМосковский государственный медико-стоматологический университетРоссияMoscow State University of Medicine and DentistryRussian Federation20112101201675620627Copyright © Perova N.V., Metel'skaya V.A., Sokolov E.I., Shchukina G.N., Fomina V.M., 20162016Перова Н.В., Метельская В.А., Соколов Е.И., Щукина Г.Н., Фомина В.М.Perova N.V., Metel'skaya V.A., Sokolov E.I., Shchukina G.N., Fomina V.M.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.rpcardio.online/jour/article/view/937

The world publications data about the impact of consumption and the fatty acids ratio in consumed fats on the development of cardiovascular diseases and acute complications due to atherothrombosis is presented. The role of some fat characteristics is discussed: hydrogenous saturation with different number of double bonds, various lengths of hydrocarbonic chains and molecule geometry , etc. Fat structure is more crucial for cardiovascular risk than total amount of consumed saturated fat. Favorable fat structure should include physiologic amounts of saturated fatty acids (8-10%), polyunsaturated fatty acids, especially n-3 long-chain, a significant amount (up to 20% of calories) of monounsaturated fatty acids, a very small amount of trans fatty acid form. Such a fatty product is useful in antiatherogenic diets.

Представлен аналитический обзор данных мировой литературы об особенностях влияния на развитие болезней системы кровообращения и их острых осложнений, обусловленных атеротромбозом, общего потребления и соотношения в потребляемых людьми жирах жирных кислот различной насыщенности водородом с различным количеством двойных связей, различной длиной углеводородной цепи, различной геометрической конфигурацией молекул. Показано, что не столько общее количество потребляемого насыщенного жира усугубляет риск болезней системы кровообращения, сколько определяющим моментом является состав жира. Полезным следует считать физиологичное количество насыщенных жирных кислот (8-10%), сочетающееся с наличием полиненасыщенных жирных кислот , особенно n-3 длинноцепочечных, значительным (до 20% калорийности) количеством мононенасыщенных жирных кислот , очень малым количеством транс-форм жирных кислот. Такой жировой продукт можно использовать в антиатерогенной диете.

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The authors declare that there are no conflicts of interest present.