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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">rpcardio</journal-id><journal-title-group><journal-title xml:lang="en">Rational Pharmacotherapy in Cardiology</journal-title><trans-title-group xml:lang="ru"><trans-title>Рациональная Фармакотерапия в Кардиологии</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1819-6446</issn><issn pub-type="epub">2225-3653</issn><publisher><publisher-name>«SILICEA-POLIGRAF» LLC</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.20996/1819-6446-2015-11-3-309-316</article-id><article-id custom-type="elpub" pub-id-type="custom">rpcardio-97</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>POINT OF VIEW</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ТОЧКА ЗРЕНИЯ</subject></subj-group></article-categories><title-group><article-title>OMEGA-3 FATTY ACIDS AND AGE-RELATED DISEASES: REALITIES AND PROSPECTS</article-title><trans-title-group xml:lang="ru"><trans-title>ОМЕГА-3 ПОЛИНЕНАСЫЩЕННЫЕ ЖИРНЫЕ КИСЛОТЫ И ВОЗРАСТ-АССОЦИИРОВАННЫЕ ЗАБОЛЕВАНИЯ: РЕАЛИИ И ПЕРСПЕКТИВЫ</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Драпкина</surname><given-names>О. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Drapkina</surname><given-names>O. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>д.м.н., профессор кафедры пропедевтики внутренних болезней лечебного факультета Первого МГМУ им. И.М. Сеченова; зав. отделением кардиологии Клиники пропедевтики внутренних болезней, гастроэнтерологии и гепатологии им. В.Х. Василенко</p><p>119991, Москва, ул. Трубецкая, 8, стр. 2</p></bio><bio xml:lang="en"><p>Trubetskaya ul. 8-2, Moscow, 119991 Russia</p></bio><email xlink:type="simple">drapkina@bk.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шепель</surname><given-names>Р. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Shepel'</surname><given-names>R. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>аспирант той же кафедры; врач-кардиолог той же клиники</p><p>119991, Москва, ул. Трубецкая, 8, стр. 2</p></bio><bio xml:lang="en"><p>Trubetskaya ul. 8-2, Moscow, 119991 Russia</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Первый Московский государственный медицинский университет им. И.М. Сеченова</institution><country>Россия</country></aff><aff xml:lang="en"><institution>I.M. Sechenov First Moscow State Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2015</year></pub-date><pub-date pub-type="epub"><day>21</day><month>09</month><year>2015</year></pub-date><volume>11</volume><issue>3</issue><fpage>309</fpage><lpage>316</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Drapkina O.M., Shepel' R.N., 2015</copyright-statement><copyright-year>2015</copyright-year><copyright-holder xml:lang="ru">Драпкина О.М., Шепель Р.Н.</copyright-holder><copyright-holder xml:lang="en">Drapkina O.M., Shepel' R.N.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.rpcardio.online/jour/article/view/97">https://www.rpcardio.online/jour/article/view/97</self-uri><abstract><p>Efficacy of omega-3 fatty acids in cardiology is so high that in many countries omega-3 fatty acids are included into the treatment protocols for patients with cardiovascular diseases. This therapeutic class slows down oxidative stress and chronic inflammation processes, thereby providing a significant contribution to the complex treatment of hypertension. Besides, omega-3 fatty acids slow down the aging process and prevent the development of age-related diseases affecting the rate of telomere shortening.</p></abstract><trans-abstract xml:lang="ru"><p>Эффективность применения омега-3 полиненасыщенных жирных кислот (ПНЖК) в кардиологии настолько высока, что во многих странах препараты омега-3 ПНЖК вводятся в протоколы ведения пациентов с сердечно-сосудистой патологией. Данная группа препаратов замедляет процессы оксидативного стресса и хронического воспаления, тем самым оказывают весомый вклад в комплексное лечение гипертонической болезни. Кроме того, омега-3 ПНЖК замедляют процесс старения и предотвращают развитие возраст-ассоциированных заболеваний, влияя на скорость укорочения теломер.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>теломеры</kwd><kwd>старение</kwd><kwd>сердечно-сосудистая система</kwd><kwd>гипертоническая болезнь</kwd><kwd>оксидативный стресс</kwd></kwd-group><kwd-group xml:lang="en"><kwd>telomere</kwd><kwd>aging</kwd><kwd>cardiovascular system</kwd><kwd>hypertension</kwd><kwd>oxidative stress</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Dyerberg J., Bang H.O., Hjorne N. Fatty acid composition of the plasma lipids in Greenland Eskimos. Am J Clin Nutr. 1975; 28: 958-66.</mixed-citation><mixed-citation xml:lang="en">Dyerberg J., Bang H.O., Hjorne N. Fatty acid composition of the plasma lipids in Greenland Eskimos. 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