АРТЕРИАЛЬНАЯ ЖЕСТКОСТЬ И ХРОНИЧЕСКАЯ БОЛЕЗНЬ ПОЧЕК: ПРИЧИНЫ И ПОСЛЕДСТВИЯ
https://doi.org/10.20996/1819-6446-2014-10-1-83-91
Аннотация
Хроническая болезнь почек (ХБП) ассоциирована с повышенным сердечно-сосудистым риском. ХБП характеризуется ускоренным старением сосудов, в которых связанное с возрастом повышение артериальной жесткости усугубляется рядом связанных с уремией процессов. Повышенная жесткость артерий связана со структурными и функциональными нарушениями, а также с увеличением сердечно-сосудистой смертности у пациентов с ХБП.
Повышенная артериальная ригидность выявляется уже на начальной стадии хронической болезни почек. Анализируются современные представления о механизмах повышения риска развития сердечно-сосудистых осложнений при ХБП, факторах, способствующих утрате эластичности артерий, последствиях повышения артериальной ригидности. Представлены данные, иллюстрирующие двусторонний характер взаимосвязи ХБП и артериальной ригидности, механизмы ускорения прогрессирования артериальной ригидности при ХБП.
Об авторах
Ж. Д. Кобалава
Российский университет дружбы народов, Москва
Россия
Россия
Кобалава Жанна Давидовна – доктор медицинских наук, профессор, заведующая кафедрой пропедевтики внутренних болезней медицинского факультета РУДН
Ю. В. Котовская
Российский университет дружбы народов, Москва
Россия
Россия
Котовская Юлия Викторовна – доктор медицинских наук, профессор, профессор кафедры пропедевтики внутренних болезней медицинского факультета
С. В. Виллевальде
Российский университет дружбы народов, Москва
Россия
Россия
Виллевальде Светлана Вадимовна – доктор медицинских наук, доцент, профессор кафедры пропедевтики внутренних болезней медицинского факультета
А. Е. Соловьева
Российский университет дружбы народов, Москва
Россия
Россия
Соловьева Анжела Евгеньевна – ординатор кафедры пропедевтики внутренних болезней медицинского факультета
И. М. Амирбегишвили
Российский университет дружбы народов, Москва
Россия
Россия
Амирбегишвили Ирма Михайловна – докторант кафедры пропедевтики внутренних болезней медицинского факультета
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Рецензия
Для цитирования:
Кобалава Ж.Д., Котовская Ю.В., Виллевальде С.В., Соловьева А.Е., Амирбегишвили И.М. АРТЕРИАЛЬНАЯ ЖЕСТКОСТЬ И ХРОНИЧЕСКАЯ БОЛЕЗНЬ ПОЧЕК: ПРИЧИНЫ И ПОСЛЕДСТВИЯ. Рациональная Фармакотерапия в Кардиологии. 2014;10(1):83-91. https://doi.org/10.20996/1819-6446-2014-10-1-83-91
For citation:
Kobalava J.D., Kotovskaya Yu.V., Villevalde S.V., Soloveva A.E., Amirbegishvili I.M. ARTERIAL STIFFNESS AND CHRONIC KIDNEY DISEASE: CAUSES AND CONSEQUENCES. Rational Pharmacotherapy in Cardiology. 2014;10(1):83-91. (In Russ.) https://doi.org/10.20996/1819-6446-2014-10-1-83-91
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