DISORDERS OF THE AUTONOMIC NERVOUS SYSTEM IN THE CARDIOLOGY PRACTICE: FOCUS ON THE ANALYSIS OF HEART RATE VARIABILITY
https://doi.org/10.20996/1819-6446-2015-11-4-426-430
Abstract
Heart rate variability (HRV) in patients with ischemic heart disease, a life-threatening heart rhythm disorders, as well as diabetes mellitus (DM) is considered. A significant association between the autonomic regulation of the cardiovascular system and death from cardiovascular causes is identified. The reactions of the autonomic nervous system (ANS) can serve as a precipitating factor of arrhythmias in patients with heart disorders. Analysis of HRV at rest is the main and informative method for determination of the ANS disorders. HRV decreases greatly in patients with acute myocardial infarction, cardiac arrhythmia, and DM, predicting a high risk of death. The leading cause of death in diabetic patients is cardiac autonomic neuropathy, with the development of "silent" ischemia and painless myocardial infarction. Autonomic regulation of the heart rate should be assessed for early diagnosis and prevention of complications in the form of sudden death.
About the Authors
E. B. Akhmedova
State Research Centre for Preventive Medicine
Russian Federation
Petroverigsky per. 10, Moscow, 101990 Russia
Russian Federation
Petroverigsky per. 10, Moscow, 101990 Russia
B. U. Mardanov
State Research Centre for Preventive Medicine
Russian Federation
Petroverigsky per. 10, Moscow, 101990 Russia
Russian Federation
Petroverigsky per. 10, Moscow, 101990 Russia
M. N. Mamedov
State Research Centre for Preventive Medicine
Russian Federation
Petroverigsky per. 10, Moscow, 101990 Russia
Russian Federation
Petroverigsky per. 10, Moscow, 101990 Russia
References
1. Task Force of the European Society of Cardiology and the North American Society of Pacing and Electrophysiology. Heart rate variability: Standards of measurement, physiological interpretation and clinical use. Circulation 1996; 93: 1043-65.
2. Jouven X., Empana J.P., Schwartz P.J. et al. Heart-rate profile during exercise as a predictor of sudden death. N Engl J Med 2005; 352(19): 1951-8.
3. Carney R.M., Blumenthal J.A., Freedland K.E. et al. Low heart rate variability and the effect of depression on post-myocardial infarction mortality. Arch Intern Med 2005; 165(13): 1486-91.
4. Bigger J. T. Jr, Fleiss J. L., Rolnitzky L. M. et al. The ability of several short-term measures of RR variability to predict mortality after myocardial infaction. Circulation 1993; 88: 927-34.
5. Huang J., Sopher S. M., Leatham E. et al. Heart rate variability depression in patients with unstable angina. Am Heart J 1995; 130: 772-9.
6. Bokeria L.A., Bokeria O.L., Volkovskaya I.V. Heart rate variability: methods of measurement, interpretation and clinical use. Annali Aritmologii 2009; 4: 29. In Russian (Бокерия Л.А., Бокерия О.Л., Вол-ковская И.В. Вариабельность сердечного ритма: методы измерения, интерпретации, клиниче-ское использование. Анналы Аритмологии 2009; 4: 29).
7. Simon S. R., Powel L. H., Bartzokis T. C., Hoch D. H. A new system for classification of cardiac death as arrhythmic, ischemic, or due to myocardial pump failure. Am J Cardiol 1995; 76(12): 896-8.
8. World Health Organization. Diabetes Programme. Country and regional data on diabetes. Available at: http://www.who.int/diabetes/facts/world_figures/en/. Verified 08/20/2015.
9. Unwin N, Gan D, Whiting D. The IDF Diabetes altas: providing evidence, raising awareness and promoting action. Diabetes Res Clin Pract 2010; 87: 2-3.
10. Bissinger A, Ruxer J, Ahmed RB, Lubinski A. Heart rate turbulence in patients with poorly controlled diabetes mellitus type 2. Arch Med Sci 2014;10(6):1073-7.
11. Dedov II, Balabolkin MI, Klebanovа EM, et al. Diabetes mellitus: pathogenesis, classification, diagnosis and treatment. Manual for physicians. Moscow: ESC RAMS; 2003. In Russian (Дедов И.И., Ба-лаболкин М.И., Клебанова Е.М., и др. Сахарный диабет: патогенез, классификация, диагно-стика и лечение. Пособие для врачей. Москва: ЭНЦ РАМН; 2003).
12. Healthcare in Russia. The official publication of the Federal State Statistics Service. Moscow: Rosstat; 2009. In Russian (Здравоохранение в России. Официальное издание Федеральной службы го-сударственной статистики. Москва: Росстат; 2009).
13. Pop-Busui R, Cleary PA, Braffett BH, et al.; DCCT/EDIC Research Group.Association between cardiovascular autonomic neuropathy and left ventricular dysfunction: DCCT/EDIC study (Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications).J Am Coll Cardiol 2013;61(4):447-54.
14. Moon SS, Choi YK, Seo HA, et al. Relationship between cardiovascular autonomic neuropathy and coronary artery calcification in patients with type 2 diabetes. Endocr J 2010;57(5):445-54.
15. Valensi P1, Sachs RN, Harfouche B, et al. Predictive value of cardiac autonomic neuropathy in diabetic patients with or without silent myocardial ischemia. Diabetes Care 2001;24(2):339-43.
16. Ziegler D, Gries FA, Spüler M, Lessmann F. The epidemiology of diabetic neuropathy. Diabetic Cardiovascular Autonomic NeuropathyMulticenter Study Group. J Diabetes Complications 1992;6(1):49-57.
17. Sokolov E.V. Diabetic Heart: cardiomyopathy causes the development. Problemi endokrinologii 1996; 6:14-6. In Russian (Соколов Е.В. Диабетическое сердце: причины развитие кардиомиопатии. Проблемы Эндокринологии 1996; 6:14-6).
18. Chun MY, Park HK, Hwang HS, et al. The Association between Symptoms of Autonomic Neuropathy and the Heart Rate Variability in Diabetics. Korean J Fam Med 2011;32(5):292-8.
Review
For citations:
Akhmedova E.B., Mardanov B.U., Mamedov M.N. DISORDERS OF THE AUTONOMIC NERVOUS SYSTEM IN THE CARDIOLOGY PRACTICE: FOCUS ON THE ANALYSIS OF HEART RATE VARIABILITY. Rational Pharmacotherapy in Cardiology. 2015;11(4):426-430. (In Russ.) https://doi.org/10.20996/1819-6446-2015-11-4-426-430
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