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Rational Pharmacotherapy in Cardiology

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Thoracalgia in a Patient with Determined Coronary Heart Disease. Is there Always a Relapse of Angina Pectoris?

https://doi.org/10.20996/1819-6446-2020-02-05

Abstract

This article presents a clinical case of a 62-year-old man with a long history of coronary heart disease and smoking, whose main complaint upon admission to the hospital was voice hoarseness and atypical pain syndrome in the chest. During a preliminary medical examination, attention was paid to the clinical picture, atypical for a coronary heart disease – voice hoarseness was identified as a manifestation of the recurrent nerve compression, or cardio-vocal syndrome. Given the lack of connection between the chest pain and physical exertion, a high index of a smoking person as well as signs of the recurrent nerve compression syndrome, a multi-spiral computer tomography with contrasting of the chest organs was performed (in line with official recommendations of the Russian Associations of Oncologists and Otolaryngologists). The results revealed a proliferative lesion of the mediastinum and multiple focal lesions of both lungs. A subsequent thoracoscopy and biopsy confirmed the mediastinal form of a lung cancer. Promptly initiated poly-chemotherapy allowed stabilizing the patient’s condition and significantly improving his prospects. In this context, the article discusses the complexity of a timely diagnosis of a primary lung cancer and emphasizes the need to focus on specific and unique features of the disease course as well as on a broader clinical picture. Tactics of a multidisciplinary approach allows making a diagnosis in a timely manner, significantly improving the effectiveness of therapy and patient’s survival prognosis.

About the Authors

O. M. Drapkina
National Medical Research Center for Preventive Medicine
Russian Federation

Oxana M. Drapkina – MD, PhD, Professor, Corresponding Member of the Russian Academy of Sciences, Director, National Medical Research Center for Therapy and Preventive Medicine

Petroverigsky per. 10, Moscow, 101990





A. A. Zeynapur
National Medical Research Center for Preventive Medicine
Russian Federation

Aida A. Zeynapur – MD, PhD, Head of Admission Department

Petroverigsky per. 10, Moscow, 101990



A. S. Klevina
National Medical Research Center for Preventive Medicine
Russian Federation

Alina S. Klevina – MD, Cardiologist, Admission Department

Petroverigsky per. 10, Moscow, 101990





O. B. Vasileva
National Medical Research Center for Preventive Medicine
Russian Federation

Olga B. Vasileva – MD, Cardiologist, Admission Department

Petroverigsky per. 10, Moscow, 101990



References

1. Lung cancer. Clinical guidelines, 2018. Association of Oncologists of Russia. Russian society of clinical oncology. [cited by Dec 11, 2019]. Available from: http://www.oncology.ru/association/clinical-guidelines/2018/rak_legkogo_pr2018.pdf. (In Russ.)

2. Paresis and paralysis of the larynx. Clinical guidelines, 2014. National Medical Association of Otorhinolaryngologists [cited by Dec 11, 2019]. Available from: http://www.consultant.ru/document/cons_doc_LAW_327013/. (In Russ.)

3. Fetterolf G., Norris G.W. The anatomical explanation of the paralysis of the left recurrent laryngeal nerve found in certain cases of mitral stenosis. Am J Med Sci. 1911;141:625-38.

4. Kirasirova E.A., Piminidi O.К., Lafutkina N.V., et al. The role of the cardiovascular system pathology in the development of recurrent laryngeal nerve palsy. Annals of Surgery. 2016;21(6):372-6 (In Russ.)

5. Breast Cancer Screening and Diagnosis, Version 3.2018, NCCN Clinical Practice Guidelines in Oncology. J Natl Compr Canc Netw. 2018;16(11):1362-89. DOI: 10.6004/jnccn.2018.0083.

6. Lung Cancer Screening, Version 3.2018. NCCN Clinical Practice Guide lines in Oncology. J Natl Compr Canc Netw. 2018;16(4):412-41. DOI: 10.6004/jnccn.2018.0020.

7. Murugan V.A., Kalra M.K., Rehani M., Digumarthy S.R. Lung Cancer Screening: Computed Tomography Radiation and Protocols. J Thorac Imaging. 2015;30(5):283-9. DOI: 10.1097/RTI.0000000000000150.

8. Li C.C., Matthews A.K., Dong X. Examination of Chronic Smoking Behavior and Eligibility for Low-Dose Computed Tomography for Lung Cancer Screening Among Older Chinese Male Smokers. J Gerontol A Biol Sci Med Sci. 2017;72(suppl_1):S22-S25. DOI:10.1093/gerona/glw202.

9. Hirsch F.R., Scagliotti G.V., Mulshine J.L., et al. Lung cancer: current therapies and new targeted treatments. Lancet. 2017;389(10066):299-311. DOI: 10.1016/S0140-6736(16)30958-8.


Review

For citations:


Drapkina O.M., Zeynapur A.A., Klevina A.S., Vasileva O.B. Thoracalgia in a Patient with Determined Coronary Heart Disease. Is there Always a Relapse of Angina Pectoris? Rational Pharmacotherapy in Cardiology. 2020;16(1):46-50. (In Russ.) https://doi.org/10.20996/1819-6446-2020-02-05

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ISSN 1819-6446 (Print)
ISSN 2225-3653 (Online)