Features of Risk Stratification, Diagnosis and Secondary Prevention in Patients with Multifocal Arterial Disease. Part 2: Treatment Options
https://doi.org/10.20996/1819-6446-2021-03-02
Abstract
The similarity of the pathogenesis of atherosclerosis and atherothrombotic complications, regardless of their location, makes the approaches to secondary prevention similar, which include lifestyle modification, pharmacotherapy of hemodynamic disorders, metabolic changes and hemostasis. Secondary prophylaxis in patients with multifocal arterial lesions using antihypertensive, antithrombotic and lipid-lowering therapy provides a more pronounced decrease in the incidence of cardiovascular complications than in lesions of single vascular lesions due to a higher initial risk. However, these treatments do not reduce the risk to the level that is achieved by treating patients with less atherosclerotic lesion. In this regard, it is of interest to use the currently available new methods and regimens of drug therapy in patients with multifocal arterial lesions, which make it possible to more intensively influence the mechanisms of atherosclerosis progression and more effectively prevent the development of its complications.
Keywords
cardiovascular disease,
polyvascular disease,
screening,
risk assessment,
secondary prevention,
antithrombotic therapy
Supporting agencies: The publication of the article is supported by Bayer, but it did not affect his own opinion of the authors
About the Authors
V. G. Grachev
Urals State Medical University
Russian Federation
Russian Federation
Vadim G. Grachev - eLibrary SPIN 3097-0735
Yekaterinburg
S. S. Vedenskaya
Urals State Medical University
Russian Federation
Russian Federation
Svetlana S. Vedenskaya - eLibrary SPIN 5248-9958
Yekaterinburg
O. G. Smolenskaya
Urals State Medical University
Russian Federation
Russian Federation
Olga G. Smolenskaya - eLibrary SPIN 5443-9382
Yekaterinburg
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For citations:
Grachev V.G., Vedenskaya S.S., Smolenskaya O.G. Features of Risk Stratification, Diagnosis and Secondary Prevention in Patients with Multifocal Arterial Disease. Part 2: Treatment Options. Rational Pharmacotherapy in Cardiology. 2021;17(2):239-248. (In Russ.) https://doi.org/10.20996/1819-6446-2021-03-02
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