EFFECT OF DIFFERENT GLUCOSE BLOOD LEVELS ON THE DEVELOPMENT OF CARDIOVASCULAR DISEASES AND COMPLICATIONS
https://doi.org/10.20996/1819-6446-2013-9-1-74-78
Abstract
Diabetes mellitus (DM) is one of the health and social problems of modern health care. The main causes of death in patients with DM are macrovascular complications. Intensive hypoglycemic therapy is recommended to prevent complications; however it can increase the risk of severe hypoglycemia with subsequent growth rate of mortality. Glucose blood levels should be monitored to reduce the risk of cardiovascular disease and death, as well as control of normoglycemia and risk factors are needed. DM pathogenesis and prevalence are considered, and effects of glucose blood level on its outcomes are analyzed.
About the Authors
E. V. Akhmedova
State scientific research centre of preventive medicine, Moscow
Russian Federation
Russian Federation
Z. A. Toguzova
North Ossetian State Medical Academy, Vladikavkaz
Russian Federation
Russian Federation
M. N. Mamedov
State scientific research centre of preventive medicine, Moscow
Russian Federation
Russian Federation
References
1. Zimmet P, Dowse G, Finch C, Serjeantson S, King H. The epidemiology and natural history of NIDDMlessons from the South Pacific. Diabetes Metab Res Rev 1990; 6:91–124.
2. Ginter E, Simko V. Global prevalence and future of diabetes mellitus. Adv Exp Med Biol. 2012;771:35– 41.
3. Unwin N, Gan D, Whiting D. The IDF Diabetes altas: providing evidence, raising awareness and promoting action. Diabetes Res Clin Pract 2010; 87: 2–3
4. Arredondo A. Diabetes: a global challenge with high economic burden for public health systems and society. Am J Public Health 2013;103(2):e1–2.
5. Demidova I.Yu., Glinkina I.V., Perfilova A.N. Type 2 diabetes mellitus (pathogenesis and treatment). Consilium-Medicum 2000; 2(5): 34–41. Russian (Демидова И.Ю., Глинкина И.В., Перфилова А.Н. Сахарный диабет типа 2 (патогенез и лечение). Consilium-Medicum 2000; 2(5): 34–41).
6. Demidova T.Yu., Ametov A.S. Insulin dependent diabetes mellitus – a manifestation of heterogeneous disorders of glucose metabolism. Russkiy Meditsinskiy Zhurnal 1998; 6(12): 757–758. Russian (Демидова Т.Ю., Аметов А.С. Инсулиннезависимый сахарный диабет — проявление гетерогенных нарушений углеводного обмена. Русский Медицинский Журнал 1998; 6(12): 757–758).
7. Diedrich L, Sandoval D, Davis SN. Hypoglycemia is connected autonomic failure. Clin Auton Res 2002;12(5):358–65
8. Turnbull FM, Abraira C, Anderson RJ , et al. Intensive glucose control and macrovascular outcomes in type 2 diabetes. Diabetologia 2009; 52: 2288–2298.
9. Dluhy RG and McMahon GT. Intensive glucemic control in the ACCORD and ADVANCE trials. N Engl J Med 2008; 358: 2630–2633.
10. Gitt AK, Bramlage P, Binz C, et al. (for the DiaRegis Study Group). Hypoglycaemia is more frequent in type 2 diabetic patients with co-morbid vascular disease: an analysis of the DiaRegis registry .Eur J Prev Cardiol 2012; 19(4):765–72.
11. Anand SS, Dagenais GR, Mohan V, et al. Glucose levels are associated with cardiovascular disease and death in an international cohort of normal glycaemic and dysglycaemic men and women: the EpiDREAM cohort study. Eur J Card Prev Rehab 2012; 19(4):755–64.
12. Sarwar N, Gao P , Seshasai SR, et al. Emerging Risk Factors Collaboration. Diabetes mellitus, fasting blood glucose concentration, and risk of vascular disease : a collaborative meta-analysis of 102 prospective studies. Lancet 2010; 375(9733): 2215–2222.
13. Expert Committee on the Diagnosis and Classification of Diabetes Mellitus. Follow-up report on the diagnosis of diabetes mellitus. Diabetes Care 2003; 26: 3160–7.
14. 2006 WHO/IDF Guidelines on the diagnostic criteria for diabetes and impaired glycaemic regulation. Diabetes Medicine 23 (Suppl 4); 2006: 570–576.
15. Healthcare in Russia. Statistical Yearbook. Moscow: Rosstat, 2009. Russian (Здравоохранение в Росcии. Статистические сборник. М.: Росстат; 2009).
16. Lowel H, Koenig W, Engel S, et al. The impact of diabetes mellitus on survival after myocardial infarction: can it be modified by drug treatment? Results of a population-based myocardial infarction register followup study. Diabetologia 2000; 43: 218–226.
17. Johnston CS, Sidney S, Bernstein AL, Gress DR. A comparison of risk factors for recurrent TIA and stroke in patients diagnosed with TIA. Neurology 2003; 28: 280–285
18. Meijer WT, Hoes AW, Rutgers D et al. Peripheral arterial disease in the elderly: the Rotterdam Study. Arterioscler Thromb Vac Biol 1998; 18: 185–192.
Review
For citations:
Akhmedova E.V., Toguzova Z.A., Mamedov M.N. EFFECT OF DIFFERENT GLUCOSE BLOOD LEVELS ON THE DEVELOPMENT OF CARDIOVASCULAR DISEASES AND COMPLICATIONS. Rational Pharmacotherapy in Cardiology. 2013;9(1):74-78. (In Russ.) https://doi.org/10.20996/1819-6446-2013-9-1-74-78
Views:
774
.jpg)
Email this article 