ФИКСИРОВАННАЯ НИЗКОДОЗОВАЯ КОМБИНАЦИЯ ЛИЗИНОПРИЛА И ГИДРОХЛОРТИАЗИДА В ПРОФИЛАКТИКЕ СЕРДЕЧНО-СОСУДИСТЫХ СОБЫТИЙ У БОЛЬНЫХ АРТЕРИАЛЬНОЙ ГИПЕРТОНИЕЙ
https://doi.org/10.20996/1819-6446-2010-6-5-697-702
Аннотация
Обсуждаются особенности механизма действия и клинического применения фиксированной низкодозовой комбинации лизиноприла и гидрохлортиазида. Показана целесообразность комбинирования ингибитора АПФ и тиазидового диуретика, что обусловлено более эффективным контролем артериального давления, потенцированием органопротективного действия и снижением риска побочных эффектов. Представлены результаты клинических исследований эффективности и безопасности препарата у больных артериальной гипертонией с различными сопутствующими заболеваниями.
Об авторах
А. О. Шевченко
Российский государственный медицинский университет им. Н.И. Пирогова
Россия
Россия
д.м.н., профессор кафедры кардиологии
117997, Москва, ул. Островитянова, д. 1
О. П. Шевченко
Российский государственный медицинский университет им. Н.И. Пирогова
Россия
Россия
д.м.н., профессор, заведующий той же кафедрой, декан Факультета усовершенствования врачей
117997, Москва, ул. Островитянова, д. 1
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Рецензия
Для цитирования:
Шевченко А.О., Шевченко О.П. ФИКСИРОВАННАЯ НИЗКОДОЗОВАЯ КОМБИНАЦИЯ ЛИЗИНОПРИЛА И ГИДРОХЛОРТИАЗИДА В ПРОФИЛАКТИКЕ СЕРДЕЧНО-СОСУДИСТЫХ СОБЫТИЙ У БОЛЬНЫХ АРТЕРИАЛЬНОЙ ГИПЕРТОНИЕЙ. Рациональная Фармакотерапия в Кардиологии. 2010;6(5):697-702. https://doi.org/10.20996/1819-6446-2010-6-5-697-702
For citation:
Shevchenko A.O., Shevchenko O.P. FIXED LOW-DOSE COMBINATION OF LISINOPRIL AND HYDROCHLOROTHIAZIDE IN THE PREVENTION OF CARDIOVASCULAR EVENTS IN HYPERTENSIVE PATIENTS. Rational Pharmacotherapy in Cardiology. 2010;6(5):697-702. (In Russ.) https://doi.org/10.20996/1819-6446-2010-6-5-697-702
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