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Rational Pharmacotherapy in Cardiology

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Vol 17, No 4 (2021) Association of SCN5A gene polymorphism with dilated cardiomyopathy Abstract  similar documents
S. Yu. Nikulina, O. O. Kuznetsova, A. A. Chernova, G. V. Matyushin, A. A. Gurazheva, V. N. Maksimov
"... in patients with IDC compared to the control group of the rs1805124 polymorphism of the SCN5A gene ..."
 
Vol 3, No 5 (2007) IDIOPATHIC SICK SINUS SYNDROME Abstract  similar documents
S. Y. Nikulina, V. A. Schulman, A. A. Chernova
 
Vol 8, No 6 (2012) GENETIC PREDICTORS OF IDIOPATHIC SICK SINUS SYNDROME Abstract  similar documents
A. A. Chernova, S. Yu. Nikulina, S. S. Tret'yakova
 
Vol 13, No 3 (2017) GENETIC ASPECTS OF MODIFIABLE RISK FACTORS ASSOCIATED WITH ARTERIAL HYPERTENSION BY THE EXAMPLE OF THE INDIGENOUS POPULATION OF MOUNTAIN SHORIYA Abstract  similar documents
T. A. Mulerova, G. V. Artamonova, M. I. Voevoda, O. V. Gruzdeva, M. Yu. Ogarkov, O. L. Barbarash
"... in indigenous population for genotype D/D ACE gene, in non-indigenous representatives – for genotype D/D ADRA2B ..."
 
Vol 17, No 5 (2021) Pharmacogenetic Aspects of Postoperative Anesthesia with Ketoprofen in Cardiac Surgery Patients Abstract  similar documents
T. E. Morozova, D. A. Shatsky, N. V. Shikh, E. V. Shikh, T. B. Andrushchyshina, M. V. Lukina, A. A. Kachanova, Z. A. Sozaeva, G. N. Shuev, N. P. Denisenko, E. А. Grishina, D. A. Sychev
"... . Results. In patients with genotypes GA and GG for the allelic variant CYP2D6*4, significant differences ..."
 
Vol 20, No 5 (2024) Association between renin-angiotensin system gene polymorphism and cardio-ankle vascular index in patients with COVID-19 Abstract  similar documents
V. I. Podzolkov, A. E. Bragina, E. S. Ogibenina, I. I. Shvedov, A. R. Komelkova
"... . Also alleles and genotypes of several polymorphic markers were identified by real-time polymerase chain ..."
 
Vol 15, No 5 (2019) Association of rs556621 Polymorphism with Development of Stroke in Patients with Cardiovascular Pathology Abstract  similar documents
S. Yu. Nikulina, V. A. Shulman, A. A. Chernova, S. V. Prokopenko, D. A. Nikulin, I. M. Platunova, S. S. Tretyakova, V. N. Maksimov, A. A. Gurazheva
"... differences in the frequencies of genotypes and single nucleotide polymorphism rs556621 alleles (G>T ..."
 
Vol 19, No 5 (2023) Pharmacogenetics and pharmacokinetics of rivaroxaban in patients with atrial fibrillation and chronic kidney disease Abstract  similar documents
N. A. Shatalova, D. A. Sychev, K. B. Mirzaev, A. I. Kochetkov, E. Yu. Ebzeeva, V. B. Dashabylova, P. O. Bochkov, S. N. Tuchkova, S. V. Glagolev
"... genotype than with the CT genotype of the polymorphic variant rs1045642 of the ABCB1 gene (Сmin,ss 60,5 [36 ..."
 
Vol 4, No 1 (2008) ACUTE CEREBROVASCULAR EVENTS IN PATIENTS WITH ARTERIAL HYPERTENSION: MOLECULAR GENETIC ASPECTS Abstract  similar documents
M. A. Karpenko, E. G. Shatskaya, V. N. Solntsev, M. A. Bogdanov, V. I. Larionova
"... , -455А allele and AA genotype of Fb gene, 677T allele of MTHFR. The A-allele and genotype AA of ATR1 ..."
 
Vol 13, No 6 (2017) CYP2C19 PHARMACOGENETIC TESTING FOR PERSONALIZATION OF ANTIPLATELET THERAPY IN PATIENTS WITH ACUTE CORONARY SYNDROME IN ROUTINE CLINICAL PRACTICE Abstract  similar documents
A. I. Akhmetova, E. B. Kleimenova, D. A. Sychev, O. V. Parshina, L. P. Yashina
"...  genotyping the GG, GA, AA allelic variants were detected. CYP2C19*2 PhGT revealed that genotypes GG, GA ..."
 
Vol 13, No 5 (2017) POLYMORPHISMS OF ENDOTHELIAL NITRIC OXIDE SYNTHASE GENE AS PREDICTORS OF WOLFF-PARKINSON-WHITE SYNDROME Abstract  similar documents
G. V. Matyushin, S. Yu. Nikulina, A. A. Chernova, I. I. Lebedeva, A. A. Semenchukov
"... a statistically significant prevalence of rare genotype 4b4b NOS3 gene in the control group of women (16.3%; р<0 ..."
 
Vol 17, No 4 (2021) Evaluation of the Influence of CYP2C9* 2, CYP2C9*3 Gene Polymorphisms on the Efficacy and Safety of Postoperative Analgesia with Ketoprofen in Patients after Cardiac Surgery Abstract  similar documents
T. E. Morozova, D. A. Shatsky, N. V. Shikh, E. V. Shikh, T. B. Andrushchyshina, M. V. Lukina, A. A. Kachanova, Zh. A. Sozaeva, G. N. Shuev, N. P. Denisenko, E. A. Grishina, D. A. Sychev
"... genotype of CYP2C9*3 polymorphism, the intensity of pain on the numeric rating scale scale (points ..."
 
Vol 4, No 2 (2008) EFFECT OF GENES SLCO1B1 AND MDR1 POLYMORPHISM ON ATORVASTATIN PHARMACOKINETICS AND PHARMACODYNAMICS IN PATIENTS WITH PRIMARY HYPERCHOLESTEROLEMIA: RESULTS OF PILOT PHARMACOGENETICS STUDY Abstract  similar documents
A. V. Semenov, D. A. Sichev, V. G. Kukes
"... efficacy in patients with SLCO1B1.с521СС genotype was less than this in patients with other genotypes ..."
 
Vol 20, No 1 (2024) Effect of CYP3A4/5, ABCB1 gene polymorphisms on the residual equilibrium concentration of apixaban and bleeding in patients with non-valvular atrial fibrillation and deep vein thrombosis Abstract  similar documents
l. V. Fedina, i. N. Sychev, K. V. Mirzaev, A. V. Vardanyan, S. V. Glagolev, A. A. Kachanova, P. O. Bochkov, R. V. Shevchenko, S. N. Tuchkova, I. V. Sychev, S. P. Abdullaev, D A. Sychev
"... found that patients with CT ABCB1 (rs4148738) C>T genotype had higher Cmin,ss /D value than patients ..."
 
Vol 9, No 3 (2013) IMPACT OF LOCUS 9P21.3 SINGLE NUCLEOTIDE POLYMORPHISMS ON CORONARY ATHEROSCLEROSIS SEVERITY AND LONG-TERM OUTCOMES AFTER PERCUTANEOUS CORONARY INTERVENTION IN PATIENT WITH MYOCARDIAL INFARCTION Abstract  similar documents
P. A. Shesternya, G. V. Matyushin, S. Yu. Nikulina, A. S. Sergeeva
"... were reviewed by independent angiographers who were blinded to the results of the genotyp- ing (Philips ..."
 
Vol 15, No 3 (2019) Study of the Association of V640L (rs6133) Polymorphism in the Platelet P-selectin Gene with Acetylsalicylic Acid Resistance in Patients after Coronary Bypass Surgery Abstract  similar documents
A. A. Kosinova, T. S. Mongush, M. D. Goncharov, T. N. Subbotina, K. S. Semashchenko, G. Y. Kochmareva, Yu. I. Grinshtein
"... GG genotype of the rs6133 polymorphism was 84.6%; heterozygous GT genotype – 15.4%. The amplitude ..."
 
Vol 14, No 4 (2018) Role of Single Nucleotide Polymorphism of СУР17А Gene in the Development of Stroke Abstract  similar documents
S. Yu. Nikulina, V. A. Shulman, A. A. Chernova, D. A. Nikulin, A. A. Semenchukov, O. V. Marilovceva, S. S. Tret'jakova, I. I. Lebedeva, V. N. Maksimov
"... polymorphism СУР17А. Results. The study established the association of homozygous genotype AA rs1004467 CYP17A ..."
 
Vol 7, No 2 (2011) PREDICTIVE ROLE OF CONNEXIN 40 IN THE PATHOGENESIS OF HEREDITARY SICK SINUS SYNDROME Abstract  similar documents
S. Yu. Nikulina, A. A. Chernova, V. A. Shulman, T. S. Kukushkina, M. I. Voevoda, V. N. Maksimov
"... for the polymorphism of 44G>A of gene Cx40. According to allele-specific polymerase chain reaction 3 types of genotypes ..."
 
Vol 18, No 4 (2022) The effect of rs776746 polymorphism in the CYP3A5 gene on heart rate when using bisoprolol in patients with acute coronary syndrome Abstract  similar documents
V. A. Shumkov, K. A. Zagorodnikova, S. A. Boldueva, A. A. Murzina
"... in the European population. 84 carriers of the CYP3A5*3*3 genotype (87%), 12 heterozygous carriers of the *1 ..."
 
Vol 14, No 1 (2018) NFLUENCE OF CYP4F2*3 ON RESPONSE TO CLOPIDOGREL IN PATIENTS WITH ACUTE CORONARY SYNDROME Abstract  similar documents
K. B. Mirzaev, O. D. Konova, E. A. Grishina, K. A. Ryzhikova, Zh. A. Sozaeva, D. A. Andreev, M. Y. Gilyarov, D. A. Sychev
"... testing showed that 40 (49.4%) of ACS patients had normal genotype (CC), 38 (46.9%) patients were carriers ..."
 
Vol 13, No 3 (2017) PHARMACOGENETIC ASPECTS OF NEW ORAL ANTICOAGULANTS APPLICATION Abstract  similar documents
A. V. Kryukov, D. A. Sychev, O. V. Tereshchenko
"... of genotype on rivaroxaban pharmacokinetics in the study involving the carriers of ABCB1 gene rs2032582 and rs ..."
 
Vol 6, No 5 (2010) THE POLYMORPHISM OF Α2B-ADRENERGIC RECEPTOR GENE — A NEW GENETIC MARKER OF THE HEREDITARY SICK SINUS SYNDROME Abstract  similar documents
S. Iu. Nikulina, V. A. Shulman, A. A. Chernova, D. A. Nikulin, M. I. Voevoda, V. N. Maksimov
"... their healthy relatives, 89 healthy volunteers. Results. 3 types of ADRA2B genotypes (II — homozygous wild, ID ..."
 
Vol 11, No 1 (2015) ASPECTS OF LIPID-LOWERING THERAPY WITH ATORVASTATIN IN PATIENTS WITH MYOCARDIAL INFARCTION FROM THE PERSPECTIVE OF PERSONALIZED MEDICINE Abstract  similar documents
M. V. Solodun, S. S. Yakushin
"... . Patients with SLCO1B1 c.521СC genotype had no significant reduction in the levels of atherogenic lipids (p ..."
 
Vol 4, No 2 (2008) CLINICAL AND GENETIC PECULIARITIES OF ATRIAL FIBRILLATION Abstract  similar documents
S. Y. Nikulina, V. A. Schulman, O. O. Kuznetsova, N. V. Aksjutina, P. A. Shesternja, A. A. Chernova, V. N. Maksimov, I. V. Kulikov, S. N. Ustinov, Y. L. Kazarinova, A. G. Romashchenko, M. I. Voevoda
"... of its inheritance. Сonclusion. The heterozygote genotype of gene β1-adrenoretseptors Ser49Gly is one ..."
 
Vol 16, No 3 (2020) The Relationship of Endothelial Dysfunction with the Development of Diastolic Heart Failure in Patients with Hypertension Abstract  similar documents
T. V. Kalinkina, N. V. Lareva, M. V. Chistyakova, V. V. Gorbunov
"... and genotypes: 1 mutation nitric oxide synthase 3 gene NOS3 -786 T>C; (С-786Т) in relation to indicators of left ..."
 
Vol 16, No 5 (2020) The CES1 Gene rs2244613 Minor Allele Impact on the Safety Profile of Dabigatran Etexilate: Meta-Analysis Abstract  similar documents
S. P. Abdullaev, K. B. Mirzaev, P. O. Bochkov, I. N. Sychev, D. A. Sychev
"... was identified in rs2244613 allele C carriers (genotypes AC and CC) and non-carriers (genotype AA). Quantitative ..."
 
Vol 20, No 5 (2024) The effect of the M235T polymorphism of the angiotensinogen gene on the office blood pressure during therapy with angiotensin II receptor blockers Abstract  similar documents
E. V. Rebrova, E. V. Shikh
"... , there was no statistically significant association of the M235T polymorphism genotype of the AGT with these indicators ..."
 
Vol 17, No 5 (2021) Genetic Polymorphism of beta1-adrenergic Receptors and the Effect on the Clinical Efficacy of beta-adrenoblockers Abstract  similar documents
V. N. Larina, M. V. Leonova
"... of the wild genotype Ser49Ser, as well as in carriers of the haplotype Ser49Ser/Arg389Arg. Thus, genetic ..."
 
Vol 11, No 4 (2015) INFLUENCE OF THE CYP3A4 ISOENZYME METABOLIC ACTIVITY AND CYP2C19 GENE POLYMORPHISMS ON CLOPIDOGREL ANTIPLATELET EFFECT IN PATIENTS WITH ACUTE CORONARY SYNDROME UNDERGOING PERCUTANEOUS CORONARY INTERVENTION Abstract  PDF (Eng)  similar documents
K. B. Mirzaev, R. E. Kazakov, V. V. Smirnov, D. A. Andreev, D. A. Sychev
"... with non-carriers: 53.8% in the patients with the CYP2C19*1/*2 genotype and 16.2% in subjects with the CYP2 ..."
 
Vol 7, No 4 (2011) PROTHROMBOTIC POLYMORPHISMS AND LONG-TERM PROGNOSIS OF PATIENTS WITH STABLE ISCHEMIC HEART DISEASE Abstract  similar documents
A. L. Komarov, O. O. Shahmatova, D. V. Rebrikov, D. Yu. Trophimov, T. I. Kotkina, T. A. Ilyushenko, A. D. Deev, E. P. Panchenko
"... =0.003). Homozygous carriage of MTHFR 1298 AА and TCN 776 СС “wild” genotypes increased risk of CVC 1 ..."
 
Vol 18, No 6 (2022) Effect of ABCB1 Gene Carriage and Drug-Drug Interactions on Apixaban and Rivaroxaban Pharmacokinetics and Clinical Outcomes in Patients with Atrial Fibrillation and Deep Vein Thrombosis Abstract  similar documents
L. V. Fedina, I. N. Sychev, T. D. Rastvorova, E. V. Strigunkova, A. A. Kachanova, Z. A. Sozaeva, P. O. Bochkov, A. V. Vardanyan, K. B. Mirzayev, D. A. Sychev
"... ABCB1 (rs4148738) C>T genotype encoding the carrier protein (P-gp), the plasma concentration ..."
 
Vol 19, No 3 (2023) Association of polymorphic variants of CYP2C19, P2RY12, ITGB3, ITGA2 and eNOS3 genes with high residual platelet reactivity while taking clopidogrel and acetylsalicylic acid at different terms of myocardial infarction Abstract  similar documents
T. P. Pronko, V. A. Snezhitskiy, T. L. Stepuro, A. V. Kapytski
"... ,0008. The risk of HRPR to clopidogrel is higher in AA CYP2C19 genotype carriers compared to GG genotype carriers ..."
 
Vol 6, No 3 (2010) ASSOCIATION OF CLINICAL AND GENETIC FACTORS WITH LEFT VENTRICLE HYPERTROPHY IN ARTERIAL HYPERTENSION Abstract  PDF (Eng)  similar documents
T. Yu. Kuznetsova, D. V. Gavrilov, L. M. Samohodskaya, D. V. Rebrikov, S. A. Morozova, P. I. Makarevich, A. V. Kolotvin, A. B. Balatsky, A. Yu. Postnov, S. A. Boitsov
"... of the MM genotype with LVH risk lowering was more obvious at the young age (OR 0,31, р=0,018). The A allele ..."
 
Vol 14, No 5 (2018) Associations of Cardiovascular Risk Factors and Genetic Markers with Development of Arterial Hypertension in the Population of Mountain Shoriya Abstract  similar documents
T. A. Mulerova, S. A. Maksimov, M. Yu. Ogarkov, O. V. Gruzdeva, A. V. Ponasenko, V. N. Maksimov, M. I. Voyevoda, E. S. Filimonov, G. V. Artamonova
"... rs5186 of the AGTR1 gene (OR 26.77). Genotype G/G ADRB1 gene was characterized by protective effect ..."
 
Vol 17, No 3 (2021) Comparative Characteristics of Beta-Blockers in Patients with Congenital Long QT Syndrome Abstract  similar documents
A. Yu. Proshlyakov, P. Sh. Chomakhidze, N. A. Novikova
"... . A positive result of treatment depends on the severity of long QT syndrome and its genotype. Beta-blockers ..."
 
Vol 9, No 3 (2013) INTEGRATED ASSESSMENT OF STATIN-ASSOCIATED MUSCLE DAMAGE PREDICTORS IN PATIENTS WITH ISCHEMIC HEART DISEASE Abstract  similar documents
V. I. Petrov, O. N. Smuseva, Yu. V. Solovkina
"... levels between patients with and without muscle symptoms. Patients with SLCO1B1*5 genotype were revealed ..."
 
Vol 15, No 4 (2019) Syndrome of Primary Myocardial Hypertrophy: Clinical and Morphological, Genetic Diagnostics and Comparison of Sarcomerial Variants of Cardiomyopathy and its Phenocopy Abstract  similar documents
O. V. Blagova, E. V. Zaklyazminskaya, E. A. Kogan, V. P. Sedov, G. М. Radzhabova, M. Е. Polyak, A. V. Nedostup
"... diagnostics). Genotype-positive diagnosis was established in 23.6% of patients. In patients with HCM were ..."
 
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