Preview

Rational Pharmacotherapy in Cardiology

Advanced search

Search


Order results by:     
 
Issue Title
 
Vol 20, No 1 (2024) Effect of CYP3A4/5, ABCB1 gene polymorphisms on the residual equilibrium concentration of apixaban and bleeding in patients with non-valvular atrial fibrillation and deep vein thrombosis Abstract  similar documents
l. V. Fedina, i. N. Sychev, K. V. Mirzaev, A. V. Vardanyan, S. V. Glagolev, A. A. Kachanova, P. O. Bochkov, R. V. Shevchenko, S. N. Tuchkova, I. V. Sychev, S. P. Abdullaev, D A. Sychev
"... 3A4*22 (c.522-191C>T, rs35599367), CYP3A5*3 (c.219237A>G, rs776746), ABCB1 rs1045642 (c.3435T>C ..."
 
Vol 18, No 6 (2022) Effect of ABCB1 Gene Carriage and Drug-Drug Interactions on Apixaban and Rivaroxaban Pharmacokinetics and Clinical Outcomes in Patients with Atrial Fibrillation and Deep Vein Thrombosis Abstract  similar documents
L. V. Fedina, I. N. Sychev, T. D. Rastvorova, E. V. Strigunkova, A. A. Kachanova, Z. A. Sozaeva, P. O. Bochkov, A. V. Vardanyan, K. B. Mirzayev, D. A. Sychev
"... ABCB1 (rs4148738) C>T genotype encoding the carrier protein (P-gp), the plasma concentration ..."
 
Vol 19, No 5 (2023) Pharmacogenetics and pharmacokinetics of rivaroxaban in patients with atrial fibrillation and chronic kidney disease Abstract  similar documents
N. A. Shatalova, D. A. Sychev, K. B. Mirzaev, A. I. Kochetkov, E. Yu. Ebzeeva, V. B. Dashabylova, P. O. Bochkov, S. N. Tuchkova, S. V. Glagolev
"... 1045642, rs1128503), CYP3A5 (rs776746), CYP3A4 (rs35599367) and CYP2J2 (rs890293) genes with residual ..."
 
Vol 13, No 3 (2017) PHARMACOGENETIC ASPECTS OF NEW ORAL ANTICOAGULANTS APPLICATION Abstract  similar documents
A. V. Kryukov, D. A. Sychev, O. V. Tereshchenko
"... 1045642 polymorphisms. ABCB1 gene rs4148738 polymorphism was associated with higher apixaban peak ..."
 
Vol 6, No 4 (2010) CLOPIDOGREL PHARMACOGENETICS Abstract  similar documents
A. N. Meshkov
"... of clopidogrel play an important role in the resistance development. Allel variants of the gene cytochrome CYP2C ..."
 
Vol 14, No 5 (2018) Pharmacogenetic and Clinical Predictors of Clopidogrel Insufficiency in a Patient with Atherosclerosis Obliterans of the Lower Extremities: Clinical Case Abstract  similar documents
M. A. Andreyanova, K. B. Mirzaev, D. A. Sychev, K. A. Ryzhikova, A. V. Pokrovsky, A. F. Kharazov
"... therapy in this patient, namely, the  carriage of polymorphic markers  of the  ABCB1 CT, CES1 CA and  CYP3 ..."
 
Vol 16, No 5 (2020) Pharmacokinetics and Pharmacogenetics of Apixaban Abstract  similar documents
A. V. Savinova, M. M. Petrova, N. A. Shnayder, E. N. Bochanova, R. F. Nasyrova
"... -oxidation enzymes of apixaban (CYP1A2, CYP2C8, CYP2C9, CYP2C19, CYP2J2) and transporter proteins (ABCB1 ..."
 
Vol 15, No 3 (2019) Multi-Ethnic Analysis of Cardiac Pharmacogenetic Markers of Cytochrome P450 and Membrane Transporters Genes in the Russian Population Abstract  similar documents
K. B. Mirzaev, D. S. Fedorinov, D. V. Ivashchenko, D. A. Sychev
"... », «CYP4F2», «CYP4F1», «ABCB1», «SLCO1B1», «VKORC1», «GGCX», «SULT1A1», «CULT1», «CES1», «gene», «genes ..."
 
Vol 16, No 5 (2020) New Pharmacogenetic Markers to Predict the Risk of Bleeding During Taking of Direct Oral Anticoagulants Abstract  PDF (Eng)  similar documents
K. B. Mirzaev, D. V. Ivashchenko, I. V. Volodin, E. A. Grishina, K. A. Akmalova, A. A. Kachanova, A. I. Skripka, R. M. Minnigulov, T. E. Morozova, O. A. Baturina, A. N. Levanov, T. V. Shelekhova, A. I. Kalinkin, D. A. Napalkov, A. A. Sokolova, D. A. Andreev, I. N. Sychev, P. O. Bochkov, D. A. Sychev
"... gene and 2 in the ABCB1 gene. Among the patients with bleeding who received rivaroxaban, 7 variants ..."
 
Vol 9, No 4 (2013) THE SIGNIFICANCE OF PHARMACOGENETIC CYP2C19 TESTING FOR PERSONALIZATION OF THE ANTIPLATELET THERAPY IN CARDIOLOGY PRACTICE Abstract  similar documents
K. B. Mirzaev, D. A. Sychev, D. A. Andreev, A. B. Prokofiev
"... The clinical significance  of CYP2C19 genetic polymorphism, associated with the violation ..."
 
Vol 9, No 6 (2013) THE ROLE OF P-GLYCOPROTEIN IN RATIONAL PHARMACOTHERAPY IN CARDIOLOGY Abstract  similar documents
A. V. Shulkin, E. N. Yakusheva, N. M. Popova
 
Vol 17, No 1 (2021) Pharmacokinetics and Pharmacogenetics of Dabigatran Abstract  similar documents
A. V. Savinova, V. S. Dobrodeeva, M. M. Petrova, R. F. Nasyrova, N. A. Shnayder
"... of anticoagulant therapy. It is considered that CES1 enzyme and P-glycoprotein (CES1 and ABCB1 genes accordingly ..."
 
Vol 18, No 4 (2022) The effect of rs776746 polymorphism in the CYP3A5 gene on heart rate when using bisoprolol in patients with acute coronary syndrome Abstract  similar documents
V. A. Shumkov, K. A. Zagorodnikova, S. A. Boldueva, A. A. Murzina
"... Aim. The aim of this work was to study the occurrence of the rs776746 allelic variant of the CYP3A ..."
 
Vol 6, No 4 (2010) ACC/AHA CLOPIDOGREL CLINICAL ALERT. WHAT MUST BE MODERN ANTIPLATELET THERAPY? Abstract  similar documents
S. J. Martsevich
 
Vol 14, No 4 (2018) Role of Single Nucleotide Polymorphism of СУР17А Gene in the Development of Stroke Abstract  similar documents
S. Yu. Nikulina, V. A. Shulman, A. A. Chernova, D. A. Nikulin, A. A. Semenchukov, O. V. Marilovceva, S. S. Tret'jakova, I. I. Lebedeva, V. N. Maksimov
"...  CYP17A1 is one of the many genes that can participate in the formation of predisposition ..."
 
Vol 11, No 4 (2015) INFLUENCE OF THE CYP3A4 ISOENZYME METABOLIC ACTIVITY AND CYP2C19 GENE POLYMORPHISMS ON CLOPIDOGREL ANTIPLATELET EFFECT IN PATIENTS WITH ACUTE CORONARY SYNDROME UNDERGOING PERCUTANEOUS CORONARY INTERVENTION Abstract  PDF (Eng)  similar documents
K. B. Mirzaev, R. E. Kazakov, V. V. Smirnov, D. A. Andreev, D. A. Sychev
"... Aim. Carriership of CYP2C19*2 allelic variant and reduced CYP3A4 activity can affect the formation ..."
 
Vol 17, No 4 (2021) Evaluation of the Influence of CYP2C9* 2, CYP2C9*3 Gene Polymorphisms on the Efficacy and Safety of Postoperative Analgesia with Ketoprofen in Patients after Cardiac Surgery Abstract  similar documents
T. E. Morozova, D. A. Shatsky, N. V. Shikh, E. V. Shikh, T. B. Andrushchyshina, M. V. Lukina, A. A. Kachanova, Zh. A. Sozaeva, G. N. Shuev, N. P. Denisenko, E. A. Grishina, D. A. Sychev
"... therapy in patients with CYP2C9*2 (430C>T) rs179985 and CYP2C9*3 (1075A>C) rs1057910 gene polymorphisms ..."
 
Vol 13, No 6 (2017) CYP2C19 PHARMACOGENETIC TESTING FOR PERSONALIZATION OF ANTIPLATELET THERAPY IN PATIENTS WITH ACUTE CORONARY SYNDROME IN ROUTINE CLINICAL PRACTICE Abstract  similar documents
A. I. Akhmetova, E. B. Kleimenova, D. A. Sychev, O. V. Parshina, L. P. Yashina
"... Aim. To study the use of CYP2C19 pharmacogenetic testing (PhGT) for personalization ..."
 
Vol 14, No 1 (2018) NFLUENCE OF CYP4F2*3 ON RESPONSE TO CLOPIDOGREL IN PATIENTS WITH ACUTE CORONARY SYNDROME Abstract  similar documents
K. B. Mirzaev, O. D. Konova, E. A. Grishina, K. A. Ryzhikova, Zh. A. Sozaeva, D. A. Andreev, M. Y. Gilyarov, D. A. Sychev
"... Background. Carriership of CYP4F2*3 (rs2108622, Val433Met) allelic variant can affect antiplatelet ..."
 
Vol 12, No 5 (2016) Treatment Adherence as a New Choice Factor for Optimization of Oral Anticoagulation Therapy in Patients with Atrial Fibrillation and Hemostatic Gene Polymorphisms Abstract  PDF (Eng)  similar documents
Yu. P. Skirdenko, A. V. Shustov, V. V. Zherebilov, N. A. Nikolayev
"... Aim. To evaluate treatment adherence and prevalence of CYP2C9 and VKORC1 gene mutations ..."
 
Vol 13, No 4 (2017) GENETIC PREDICTORS OF INTENSIVE LIPID-LOWERING THERAPY EFFICACY AND ITS ANTI-INFLAMMATORY EFFECTS IN VERY HIGH CARDIOVASCULAR RISK PATIENTS Abstract  similar documents
M. A. Vorobyeva, M. M. Azova, O. O. Gigani, I. V. Garmash, S. V. Villevalde, Zh. D. Kobalava
"... , 62.1% of men) were included into the study. Polymorphism Phe189Ser of the CYP3A4 (gene encoding ..."
 
Vol 14, No 1 (2018) NEW APPROACHES TO INDIVIDUALIZED CHOICE OF ORAL ANTICOAGULANTS IN PATIENTS WITH ATRIAL FIBRILLATION Abstract  similar documents
Ju. P. Skirdenko, N. A. Nikolayev
"... , polymorphism of genes CYP2C9 and VKORC1 and the structure of food preferences. Results. Persons ..."
 
Vol 9, No 5 (2013) APPLICATIONS OF PHARMACOGENETIC TESTING FOR PERSONALIZATION OF THERAPY WITH ORAL ANTICOAGULANTS IN RUSSIA Abstract  similar documents
D. A. Sychev, R. E. Kazakov, V. A. Otdelenov, A. B. Prokofiev
 
Vol 3, No 2 (2007) VARFARIN DOSE REGIME APPROACHS BASED ON PHARMACOGENETICS TEST RESULTS: REAL POSSIBILITY TO OPTIMIZE THE PHARMACOTHERAPY Abstract  similar documents
D. A. Sychev, I. M. Antonov, S. V. Zagrebin, N. A. Gasanov, V. G. Kukes
"... of polymorphisms of genes of their biotransformation (CYP2C9) and molecule-targets (VKORC1). This created basis ..."
 
Vol 17, No 1 (2021) Pharmacogenetics as a Way for Personalizing Diuretic Therapy: Focus on Torasemide Abstract  similar documents
N. M. Gafurova, E. V. Shikh, O. D. Ostroumova
"... B1 polymorphism is approximately 15.5%, the CYP2C9 polymorphism is 20%, and the OAT1 and OAT4 ..."
 
Vol 19, No 3 (2023) Association of polymorphic variants of CYP2C19, P2RY12, ITGB3, ITGA2 and eNOS3 genes with high residual platelet reactivity while taking clopidogrel and acetylsalicylic acid at different terms of myocardial infarction Abstract  similar documents
T. P. Pronko, V. A. Snezhitskiy, T. L. Stepuro, A. V. Kapytski
"... Aim. Study of the association of polymorphic variants of CYP2C19 (G681A), P2RY12 (H1/H2), ITGB3 (T ..."
 
Vol 11, No 5 (2015) Practical aspects of apixaban use in clinical practice: continuing the theme Abstract  similar documents
S. N. Bel'diev
"... Currently there are no generally accepted guidelines for the use of apixaban together with CYP3A4 ..."
 
Vol 17, No 5 (2021) Pharmacogenetic Aspects of Postoperative Anesthesia with Ketoprofen in Cardiac Surgery Patients Abstract  similar documents
T. E. Morozova, D. A. Shatsky, N. V. Shikh, E. V. Shikh, T. B. Andrushchyshina, M. V. Lukina, A. A. Kachanova, Z. A. Sozaeva, G. N. Shuev, N. P. Denisenko, E. А. Grishina, D. A. Sychev
"... Aim. Evaluation of the effect of polymorphisms of the CYP2D6, CYP2C8 genes on the efficacy ..."
 
Vol 11, No 2 (2015) PRACTICAL ASPECTS OF APIXABAN USE IN CLINICAL PRACTICE: VIEW POINT OF CLINICAL PHARMACOLOGIST Abstract  similar documents
D. A. Sychev, I. I. Sinitsina, G. Yu. Zakharova, M. I. Savel'eva, A. V. Ryabova, A. V. Kryukov, A. Yu. Yurovskii
"... laboratory control and monitoring are needed, drugs interactions (at the level of CYP3A4, P-gp), management ..."
 
Vol 18, No 3 (2022) Clinically Significant Drug Interactions for Direct Oral Anticoagulants: State of the Art Abstract  similar documents
S. R. Gilyarevsky
"... that are inhibitors or inducers of the CYP3A4 enzyme or P-glycoprotein enzymes, are determined by most of the drug ..."
 
Vol 12, No 5 (2016) Clinical and Laboratory Predictors of Major Adverse Cardiac Events in Patients with Ischemic Heart Disease Following Elective Percutaneous Coronary Intervention Abstract  similar documents
E. Z. Golukhova, M. V. Grigoryan, M. N. Ryabinina, N. I. Bulaeva
"... and laboratory biomarkers were assessed before stenting, as well as CYP2C19 genotyping after patient’s discharge ..."
 
Vol 18, No 3 (2022) Study the Association of Nucleotide Polymorphisms in Platelet Receptor and Cytochrome P450 Genes with the Development of Resistance to Antiplatelet Drugs in Patients with Coronary Artery Disease Abstract  similar documents
K. S. Semashchenko, T. S. Mongush, A. A. Kosinova, T. N. Subbotina, Y. I. Grinshtein
"... 2046934), ITGA2 (rs1126643), ITGB3 (rs5918), GP1BA (rs6065), CYP2C19*2 (rs4244285) genes ..."
 
Vol 16, No 2 (2020) Algorithm for the Choice of Anticoagulant for Patients with Atrial Fibrillation Abstract  similar documents
Yu. P. Skirdenko, N. A. Nikolaev
"... of CYP2C9 and VKORC1 genes mutations were determined at the initial examination. These indicators were ..."
 
1 - 33 of 33 Items

Search tips:

  • Search terms are case-insensitive
  • Common words are ignored
  • By default articles containing any term in the query are returned (i.e., OR is implied)
  • Make sure that a word exists in an article by prefixing it with +; e.g., +journal +access scholarly academic
  • Combine multiple words with AND to find articles containing all terms; e.g., education AND research
  • Exclude a word by prefixing it with - or NOT; e.g., online -politics or online NOT politics
  • Search for an exact phrase by putting it in quotes; e.g., "open access publishing". Hint: Quoting Chinese or Japanese words will help you to find exact word matches in mixed-language fields, e.g. "中国".
  • Use parentheses to create more complex queries; e.g., archive ((journal AND conference) NOT theses)