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The Beers criteria role in predicting bleeding during the use of direct oral anticoagulants in patients with atrial fibrillation over 80 years of age

https://doi.org/10.20996/1819-6446-2025-3157

About the Authors

M. S. Cherniaeva
Russian Medical Academy of Continuous Professional Education; Central State Medical Academy; Hospital for War Veterans No. 2
Russian Federation

Marina S. Cherniaeva

Moscow



M. A. Rozhkova
Federal Scientific and Clinical Center of the Federal Medical and Biological Agency of Russia
Russian Federation

Maria A. Rozhkova

Moscow



E. S. Ilyina
Russian Medical Academy of Continuous Professional Education
Russian Federation

Ekaterina S. Ilina

Moscow



E. A. Moiseeva
Hospital for War Veterans No. 2
Russian Federation

Ekaterina A. Moiseeva

Moscow



E. A. Gorelov
Pirogov Russian National Research Medical University
Russian Federation

Egor A. Gorelov

Moscow



L. A. Egorova
Central State Medical Academy
Russian Federation

Larisa A. Egorova

Moscow



O. M. Maslennikova
Central State Medical Academy
Russian Federation

Olga M. Maslennikova

Moscow



N. V. Lomakin
Russian Medical Academy of Continuous Professional Education; Central Clinical Hospital with Outpatient Clinic
Russian Federation

Nikita V. Lomakin

Moscow



D. A. Sychev
Russian Medical Academy of Continuous Professional Education
Russian Federation

Dmitry A. Sychev

Moscow



References

1. Van Gelder IC, Rienstra M, Bunting KV, et al; ESC Scientific Document Group. 2024 ESC Guidelines for the management of atrial fibrillation developed in collaboration with the European Association for Cardio- Thoracic Surgery (EACTS). Eur Heart J. 2024;45(36):3314-414. DOI: 10.1093/eurheartj/ehae176.

2. Arakelyan MG, Bockeria LA, Vasilieva EY, et al. 2020 Clinical guidelines for Atrial fibrillation and atrial flutter. Russian Journal of Cardiology. 2021;26(7):4594. (In Russ.) DOI: 10.15829/1560-4071-2021-4594.

3. Praskurnichy EA, Morozova OI. Clinical status and burden of atrial fibrillation in obese individuals: assessment of the effects of implementing weight control programs. The Bulletin of Contemporary Clinical Medicine. 2021;14(4):15-26. (In Russ.) DOI: 10.20969/VSKM.2021.14(4).15-26.

4. Schnabel RB, Yin X, Gona P, et al. 50 year trends in atrial fibrillation prevalence, incidence, risk factors, and mortality in the Framingham Heart Study: a cohort study. Lancet. 2015;386(9989):154-62. DOI: 10.1016/S0140-6736(14)61774-8.

5. Tkacheva ON, Vorobyova NM, Kotovskaya YuV, et al. Antithrombotic therapy in the elderly and senile age: the consensus opinion of experts of the Russian Association of Gerontologists and Geriatricians and the National Society of Preventive Cardiology. Cardiovascular Therapy and Prevention. 2021;20(3):2847. (In Russ.) DOI: 10.15829/1728-8800-2021-2847.

6. Vorobyova NM, Tkacheva ON. Use of oral anticoagulants in elderly patients with geriatric syndromes: what’s new? Rational Pharmacotherapy in Cardiology. 2020;16(6):984-93. (In Russ.) DOI: 10.20996/1819-6446-2020-12-03.

7. Sychev DA, Chernyaeva MS, Rozhkova MA, et al. Safety of direct oral anticoagulants in the treatment of atrial fibrillation in geriatric patients: focus on clinically relevant non-major bleeding. Pharmateca. 2024;2024;31(4):8-23. (In Russ.) DOI: 10.18565/pharmateca.2024.4.8-23.

8. Chernyaeva MS, Rozhkova MA, Kondrakhin AP, et al. Frequency and Structure of Clinically Relevant Non- Major Bleeding During Direct Oral Anticoagulants in Patients Over 80 Years Old with Non-Valvular Atrial Fibrillation. Effective Pharmacotherapy. 2024;20(6):28-38. DOI: 10.33978/2307-3586-2024-20-26-28-38.

9. Catalani F, Campello E, Occhipinti G, et al. Efficacy and safety of direct oral anticoagulants in older adults with atrial fibrillation: a prospective single- centre cohort study. Intern Emerg Med. 2023;18(7):1941-9. DOI: 10.1007/s11739-023-03375-9.

10. By the 2023 American Geriatrics Society Beers Criteria® Update Expert Panel. American Geriatrics Society 2023 updated AGS Beers Criteria® for potentially inappropriate medication use in older adults. J Am Geriatr Soc. 2023;71(7):2052-81. DOI: 10.1111/jgs.183724.

11. Sychev DA, Cherniaeva MS, Rozhkova MS, Vorobyova AE. Potentially Inappropriate Medications for Use in Older Adults: Beers Criteria (2023 American Geriat rics Society Guidelines). Safety and Risk of Pharmacotherapy. 2024;12(3):253-67. (In Russ.) DOI: 10.30895/2312-7821-2024-420.

12. Cherniaeva MS, Rozhkova MA, Kazakova MV, et al. Experience of using Beers criteria in clinical practice (according to Russian literature). FARMAKOEKONOMIKA. Modern Pharmacoeconomics and Pharmacoepidemiology. 2024;17(3):384-95. (In Russ.) DOI: 10.17749/2070-4909/farmakoekonomika.2024.262.

13. Sychev DA, Ostroumova OD, Pereverzev AP, et al. Risk factors for drug-induced diseases. Part 3. Drug-drug interactions and drug-food interactions. Pharmateca. 2022;29(1):10-8. (In Russ.) DOI: 10.18565/pharmateca.2022.1.10-18.

14. Sychev IN, Fedina LV, Gabrielyan DA, et al. Anticoagulant therapy with direct oral anticoagulants in conditions of polypharmacy: a course for safety. Medical Council. 2022;16(17):52-64. (In Russ.) DOI: 10.21518/2079-701X-2022-16-17-52-64.

15. Launbjerg J, Egeblad H, Heaf J, et al. Bleeding complications to oral anticoagulant therapy: multivariate analysis of 1010 treatment years in 551 outpatients. J Intern Med. 1991;229(4):351-5. DOI: 10.1111/j.1365-2796.1991.tb00358.x.


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For citations:


Cherniaeva M.S., Rozhkova M.A., Ilyina E.S., Moiseeva E.A., Gorelov E.A., Egorova L.A., Maslennikova O.M., Lomakin N.V., Sychev D.A. The Beers criteria role in predicting bleeding during the use of direct oral anticoagulants in patients with atrial fibrillation over 80 years of age. Rational Pharmacotherapy in Cardiology. 2025;21(1):39-46. (In Russ.) https://doi.org/10.20996/1819-6446-2025-3157

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ISSN 1819-6446 (Print)
ISSN 2225-3653 (Online)